Cubs vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Jun 29

Houston Astros shortstop Jeremy Pena pops out during the first inning of a spring training baseball game against the New York Mets Thursday, Feb. 27, 2025, in Port St. Lucie, Fla.
(AP Photo/Jeff Roberson)
  • The Astros are -150 favorites vs the Cubs
  • Cubs vs Astros Over / Under today: 8 Runs
  • Cubs / Astros TV Channel: SCHN | SCH2 | MARQ

The Chicago Cubs (+125) visit Daikin Park to take on the Houston Astros (-150) on Sunday, June 29, 2025. First pitch is scheduled for 2:10pm EDT in Houston, TX, TX.

This season, the Cubs are 49-34 against the spread (ATS), while the Astros are 42-41 ATS.

Cubs vs Astros Starting Pitchers Today:

  • Cubs starting pitcher: Jameson Taillon 7-5, 4.47 ERA
  • Astros starting pitcher: Framber Valdez 8-4, 2.90 ERA

Cubs vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cubs+1.5 -175O 8 -120+125
Astros -1.5 +145U 8 +100-150

Cubs vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Sunday‘s MLB game with 58.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cubs players for Sunday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

  • Nico Hoerner has hit the Home Runs Over in 3 of his last 5 games (+38.00 Units / 760% ROI)
  • Dansby Swanson has hit the Hits Over in 19 of his last 25 away games (+8.85 Units / 19% ROI)
  • Justin Turner has hit the Hits Runs and RBIs Under in 12 of his last 15 games (+8.60 Units / 41% ROI)
  • Dansby Swanson has hit the Singles Over in 16 of his last 25 away games (+8.20 Units / 30% ROI)
  • Seiya Suzuki has hit the Runs Under in 12 of his last 15 away games (+7.90 Units / 38% ROI)

And here are some favorite MLB player prop bets for Astros players for Sunday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Victor Caratini has hit the Home Runs Over in 3 of his last 7 games (+15.40 Units / 220% ROI)
  • Jake Meyers has hit the Hits Over in 21 of his last 25 games (+13.50 Units / 27% ROI)
  • Jake Meyers has hit the Singles Over in 14 of his last 15 games (+12.95 Units / 72% ROI)
  • Cam Smith has hit the Hits Runs and RBIs Over in 17 of his last 25 games at home (+10.70 Units / 38% ROI)
  • Jose Altuve has hit the Total Bases Under in his last 9 games (+9.60 Units / 64% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 42 of their last 81 games (+12.20 Units / 10% ROI)
  • The Chicago Cubs have hit the Moneyline in 47 of their last 77 games (+10.95 Units / 10% ROI)
  • The Chicago Cubs have hit the Team Total Over in 45 of their last 78 games (+6.05 Units / 6% ROI)
  • The Chicago Cubs have hit the Game Total Over in 8 of their last 10 games (+5.70 Units / 51% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 44 of their last 79 games (+5.20 Units / 5% ROI)
  • The Houston Astros have hit the Moneyline in 28 of their last 37 games at home (+17.35 Units / 34% ROI)
  • The Houston Astros have hit the Team Total Under in 51 of their last 83 games (+15.85 Units / 16% ROI)
  • The Houston Astros have hit the Game Total Under in 30 of their last 50 games (+9.35 Units / 17% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 40 games at home (+8.10 Units / 17% ROI)
  • The Houston Astros have covered the Run Line in 22 of their last 39 games at home (+7.37 Units / 16% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 41-42 against the Run Line (-0.48 Units / -0.48% ROI).

  • 49-34 when betting on the Moneyline for +8.85 Units / 7.31% ROI
  • 43-35 when betting on the total runs Over for +4.95 Units / 5.46% ROI
  • 35-43 when betting on the total runs Under for -12.45 Units / -13.53% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 42-41 against the Run Line (+2.07 Units / 2% ROI).

  • 49-34 when betting on the Moneyline for +8.55 Units / 7.86% ROI
  • 34-46 when betting on the total runs Over for -16.05 Units / -17.71% ROI
  • 46-34 when betting on the total runs Under for +8.6 Units / 9.34% ROI

Astros vs Cubs Home Run Prop Bets Today

Over Under
Christian Walker (HOU) 0.5 +350 0.5 -450
Isaac Paredes (HOU) 0.5 +400 0.5 -550
Cam Smith (HOU) 0.5 +450 0.5 -625
Yainer Diaz (HOU) 0.5 +500 0.5 -700
Seiya Suzuki (CHC) 0.5 +525 0.5 -750

Astros vs Cubs Total Hits Prop Bets Today

Over Under
Jake Meyers (HOU) 0.5 -275 0.5 +195
Nico Hoerner (CHC) 0.5 -250 0.5 +185
Jose Altuve (HOU) 0.5 -250 0.5 +190
Seiya Suzuki (CHC) 0.5 -235 0.5 +180
Isaac Paredes (HOU) 0.5 -225 0.5 +170

Astros vs Cubs RBI Prop Bets Today

Over Under
Cam Smith (HOU) 0.5 +140 0.5 -185
Yainer Diaz (HOU) 0.5 +145 0.5 -200
Seiya Suzuki (CHC) 0.5 +160 0.5 -220
Christian Walker (HOU) 0.5 +165 0.5 -220
Jose Altuve (HOU) 0.5 +175 0.5 -235

Astros vs Cubs Strikeout Prop Bets Today

Over Under
Framber Valdez (HOU) 5.5 +115 5.5 -150
Jameson Taillon (CHC) 4.5 +130 4.5 -165

Jameson Taillon has allowed a slugging percentage of .556 (89 Total Bases / 160 ABs) against right-handed batters this season — 2nd highest among qualified SPs in MLB; League Avg: .378 — second Percentile.

Jameson Taillon allowed an OBP of just .217 (129 PA’s) with runners in scoring position in the 2024 season — best among qualified SPs in MLB; League Avg: .309 — 100th Percentile.

Right-handed hitters have a groundball rate of just 31% (42/135) against Jameson Taillon this season — 3rd lowest among qualified SPs in MLB; League Avg: 43% — fourth Percentile.

Right-handed batters are hitting .281 (45-for-160) against Jameson Taillon this season — 7th highest among qualified SPs in MLB; League Avg: .235 — 10th Percentile.

Astros Starting Pitcher Stats & Trends

Opponents have a groundball rate of 61% (454/744) against Framber Valdez since last season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Opponents had a groundball rate of 61% (291/473) against Framber Valdez in the 2024 season — highest among qualified SPs in MLB; League Avg: 43% — 100th Percentile.

Opponents have a groundball rate of 60% (163/271) against Framber Valdez this season — 3rd highest among qualified SPs in MLB; League Avg: 43% — 97th Percentile.

Framber Valdez has induced opposing hitters to ground into 45 double plays in 220 opportunities (20%) since last season — best among qualified SPs in MLB; League Avg: 10% — 100th Percentile.

Cubs Keys to the Game vs. the Astros

The Cubs are 49-34 (.590) this season — tied for 3rd best in MLB; League Avg: .500.

The Cubs are 24-19 (.558) on the road this season — 3rd best in MLB; League Avg: .454.

The Cubs are 25-5 (.833) when they’ve had 10 or more hits this season — 5th best in MLB; League Avg: .745.

The Cubs were 32-10 (.762) when they scored in the first inning in the 2024 season — 3rd best in MLB; League Avg: .641.

Astros Keys to the Game vs. the Cubs

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros are 25-8 (.758) after a loss this season — best in MLB; League Avg: .494.

The Astros are 7-28 (.200) when trailing entering the 7th inning this season — tied for 4th best in MLB; League Avg: .127.

The Astros are 10-1 (.909) when they’ve had 5 or more XBH this season — tied for 5th best in MLB; League Avg: .807.

Cubs hitters are slugging .482 on the road this season — best in MLB; League Avg: .393.

Cubs hitters have an OBP of just .206 (190 PA’s) against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB; League Avg: .319.

Cubs hitters have an OBP of .331 (2,388 PA’s) against RHP this season — tied for 3rd best in MLB; League Avg: .319.

Cubs hitters have an OPS of .812 (1,721 PA’s) on the road this season — best in MLB; League Avg: .703.

Astros hitters have put just 29% of balls in play to the right side of the field this season — lowest in MLB; League Avg: 38%.

Astros hitters have put 47% of balls in play to the left side of the field this season — highest in MLB; League Avg: 38%.

Astros hitters are averaging just 3.69 pitches per plate appearance since last season — lowest in MLB; League Avg: 3.88.

Astros hitters have put 48% of balls in play to the left side of the field with runners in scoring position this season — highest in MLB; League Avg: 37%.

Opponents have a groundball rate of just 34% against Cubs pitchers over the last 14 days — 2nd lowest in MLB; League Avg: 42%.

Opponents have a groundball rate of just 32% against Cubs pitchers over the past seven days (7 games) — 2nd lowest in MLB; League Avg: 41%.

Cubs pitchers have walked 7% of batters this season — 3rd best in MLB; League Avg: 9%.

Cubs pitchers have a strikeout rate of just 38% with two-strikes this season — 2nd lowest in MLB; League Avg: 42%.

Astros pitchers have a strikeout rate of 52% with two-strikes this month (25 games) — best in MLB; League Avg: 42%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.

Opponents have a miss rate of 28% against Astros pitchers this season — best in MLB; League Avg: 25%.

Astros pitchers have a strikeout rate of 27% this season — best in MLB; League Avg: 22%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.