Cubs vs Astros Prediction, Odds & Player Prop Bets Today – MLB, May 17

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM May 17, 2023, 3:32 PM
  • The Astros are -165 favorites vs the Cubs
  • Cubs starting pitcher: Todd Smyly
  • Astros starting pitcher: Jonathan France
  • Watch the game on SportsNet SW

The Chicago Cubs (+140) visit Minute Maid Park to take on the Houston Astros (-165) on Wednesday, May 17, 2023. First pitch is scheduled for 8:10pm EDT in Houston.

The Astros are the betting favorite in this game, with the run line sitting at -1.5 (+115).

The Cubs vs Astros Over/Under is 8.5 total runs for the game.

This season, the Cubs are 19-23 against the spread (ATS), while the Astros are 21-21 ATS.

Cubs vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cubs+1.5 -140O 8.5 -110+140
Astros -1.5 +115U 8.5 -110-165

Cubs vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Wednesday‘s MLB matchup with 51.9% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cubs and Astros and up-to-date player injuries.


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We’ve highlighted some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

  • Ian Happ has hit the Runs Under in 28 of his last 35 games (+13.70 Units / 20% ROI)
  • Cody Bellinger has hit the Runs Over in 13 of his last 18 away games (+12.20 Units / 67% ROI)
  • Nico Hoerner has hit the Singles Over in 25 of his last 33 games (+10.35 Units / 16% ROI)
  • Cody Bellinger has hit the Hits Runs and RBIs Over in 14 of his last 18 away games (+10.20 Units / 49% ROI)
  • Patrick Wisdom has hit the Runs Over in 12 of his last 18 away games (+9.55 Units / 53% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Alex Bregman has hit the Total Bases Under in 32 of his last 42 games (+16.25 Units / 22% ROI)
  • Mauricio Dubon has hit the Runs Over in 19 of his last 31 games (+12.60 Units / 40% ROI)
  • Jose Abreu has hit the Total Bases Under in 27 of his last 36 games (+12.20 Units / 20% ROI)
  • Jose Abreu has hit the Runs Under in 30 of his last 39 games (+11.85 Units / 17% ROI)
  • Jose Abreu has hit the Hits Runs and RBIs Under in 24 of his last 36 games (+11.00 Units / 26% ROI)

Astros vs Cubs Home Run Prop Bets Today

Over Under
Jose Abreu 0.5 +425 0.5 -800
Seiya Suzuki 0.5 +600 0.5 -1600
Christopher Morel 0.5 +475 0.5 -1000
Patrick Wisdom 0.5 +350 0.5 -650
Kyle Tucker 0.5 +325 0.5 -550

Astros vs Cubs Total Hits Prop Bets Today

Over Under
Jose Abreu 0.5 -275 0.5 +200
Seiya Suzuki 0.5 -190 0.5 +145
Christopher Morel 0.5 -160 0.5 +125
Patrick Wisdom 0.5 -130 0.5 +100
Kyle Tucker 0.5 -250 0.5 +195

Astros vs Cubs RBI Prop Bets Today

Over Under
Jose Abreu 0.5 +140 0.5 -190
Seiya Suzuki 0.5 +180 0.5 -250
Christopher Morel 0.5 +240 0.5 -350
Patrick Wisdom 0.5 +180 0.5 -250
Kyle Tucker 0.5 +135 0.5 -185

Astros vs Cubs Strikeout Prop Bets Today

Over Under
Drew Smyly 3.5 -110 3.5 -120
P. France 5.5 -120 5.5 -110
  • The Chicago Cubs have hit the Game Total Over in their last 7 games (+7.00 Units / 92% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Under in 12 of their last 17 away games (+6.15 Units / 29% ROI)
  • The Chicago Cubs have covered the Run Line in 21 of their last 38 games (+3.35 Units / 7% ROI)
  • The Chicago Cubs have hit the Team Total Under in 6 of their last 8 away games (+3.30 Units / 33% ROI)
  • The Houston Astros have hit the Game Total Under in 13 of their last 19 games (+6.55 Units / 32% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 7 of their last 11 games (+5.35 Units / 38% ROI)
  • The Houston Astros have hit the Moneyline in 6 of their last 7 games (+5.20 Units / 54% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 13 of their last 21 games at home (+3.25 Units / 13% ROI)
  • The Houston Astros have hit the Team Total Under in 11 of their last 18 games (+2.75 Units / 13% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this MLB season, the Cubs have gone 22-20 against the Run Line (+0.7 Units / 1.34% ROI).

  • 19-23 when betting on the Moneyline for -4.8 Units / -9.46% ROI
  • 21-20 when betting on the total runs Over for -1.1 Units / -2.38% ROI
  • 20-21 when betting on the total runs Under for -3.25 Units / -7.02% ROI

Astros Against the Spread (ATS) Record

Against the spread this MLB season, the Astros have gone 21-21 against the Run Line (-2.7 Units / -4.89% ROI).

  • 23-19 when betting on the Moneyline for -4.3 Units / -7.1% ROI
  • 21-20 when betting on the total runs Over for -1.05 Units / -2.26% ROI
  • 20-21 when betting on the total runs Under for -2.85 Units / -6.2% ROI

starting pitcher – away

Astros Starting Pitcher Stats & Trends

starting pitcher – home

Cubs Keys to the Game vs. the Astros

The Cubs are just 25-38 (.397) when moneyline favorites of less than -150 since last season — 2nd lowest in MLB; League Avg: .545.

The Cubs are just 26-12 (.684) when they’ve had 5 or more XBH since last season — 3rd lowest in MLB; League Avg: .801.

The Cubs are just 1-90 (.011) when trailing entering the 9th inning since last season — tied for 2nd lowest in MLB; League Avg: .047.

The Cubs are just 2-9 (.182) when allowing 10 or more hits this season — 5th lowest in MLB; League Avg: .275.

Astros Keys to the Game vs. the Cubs

The Astros are just 0-11 (.000) when allowing 5 or more runs this season — lowest in MLB; League Avg: .205.

The Astros are 28-18 (.609) vs top 10 scoring offenses since last season — best in MLB; League Avg: .411.

The Astros are 12-1 (.923) when they’ve had 10 or more hits this season — 2nd best in MLB; League Avg: .725.

The Astros are 17-1 (.944) when leading entering the 7th inning this season — tied for 4th best in MLB; League Avg: .856.

Cubs hitters are averaging 4.09 pitches per plate appearance against RHP this season — 2nd highest in MLB; League Avg: 3.90.

Cubs hitters are averaging 4.08 pitches per plate appearance this season — highest in MLB; League Avg: 3.90.

The Cubs are batting .290 against LHP this season — 5th best in MLB; League Avg: .256.

The Cubs are batting just .277 on the first pitch of at-bats this season — lowest in MLB; League Avg: .352.

Astros hitters have just 387 strikeouts in 2,251 PA’s (17%) against LHP since last season — best in MLB; League Avg: 22%.

Astros hitters have just 66 strikeouts in 401 PA’s (17%) against LHP this season — best in MLB; League Avg: 22%.

Astros hitters have put just 33% of balls in play to the right side of the field since last season — lowest in MLB; League Avg: 37%.

14% of Astros’ hitters plate appearances have lasted only one pitch (1,039/7,624 PA’s) since last season — highest in MLB; League Avg: 11%.

Cubs pitchers have walked 27 of 375 batters (7%) when facing the leadoff batter in the inning this season — tied for 5th best in MLB; League Avg: 8%.

The Cubs pitchers have allowed division opponents to score first in just 41% of their games since last season — 3rd lowest in MLB; League Avg: 50%.

In games when their opponents have scored three or more runs in an inning, the Cubs have won just just 6% of the time this season — 2nd lowest in MLB; League Avg: 24%.

Opponents have a = 95 mph’>Hard-Hit Avg of just 35% against the Cubs pitchers this season — best in MLB; League Avg: 40%.

Astros pitchers have allowed opponents to score in three different innings in 28% of their games since last season — lowest in MLB; League Avg: 44%.

Astros pitchers have a strikeout rate of 47% with two-strikes since last season — best in MLB; League Avg: 42%.

Astros pitchers have an ERA of 3.10 (894.0 IP) on the road since last season — 2nd best in MLB; League Avg: 4.19.

Astros pitchers have a strikeout rate of 29% over the last 14 days (12 games) — best in MLB; League Avg: 22%.

Astros vs. Cubs Injuries Tonight That May Affect Prop Bets 

  • Lance McCullers Jr. (Astros): Elbow, D15
  • Jose Altuve (Astros): Thumb, D10
  • Luis Garcia (Astros): Elbow, D15
  • Michael Brantley (Astros): Shoulder, D10
  • José Urquidy (Astros): Shoulder, D15
  • Parker Mushinski (Astros): Spine, D15
  • Ethan Roberts (Cubs): Elbow, D60
  • Codi Heuer (Cubs): Elbow, D60
  • Bradley Boxberger (Cubs): Forearm, D15
  • Adrian Sampson (Cubs): Right Meniscus, D60
  • Cody Bellinger (Cubs): Knee, Day-to-Day
  • Kyle Hendricks (Cubs): Shoulder, D15
  • Nicholas Hoerner (Cubs): Hamstring, D10

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.