• The Cubs are -145 favorites vs the Cardinals
• Cubs vs Cardinals Over / Under today: 8 Runs
• Cubs / Cardinals TV Channel: FOX

The Chicago Cubs (-145) visit Busch Stadium to take on the St. Louis Cardinals (+118) on May 30, 2026. First pitch is scheduled for 7:15 pm in St. Louis, MO.

This season, the Cubs are 31-27 against the spread (ATS), while the Cardinals are 33-21 ATS.

Cubs vs Cardinals Starting Pitchers Today:

• Cubs starting pitcher: Ben Brown 1-2, 2.03 ERA
• Cardinals starting pitcher: Kyle Leahy 5-3, 4.47 ERA

Cubs vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Cubs vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Saturday‘s MLB game with 58.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Cubs players for Saturday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

• Ian Happ has hit the Home Runs Over in 4 of his last 9 away games (+17.50 Units / 194% ROI)
• Michael Busch has hit the Walks Over in 17 of his last 25 games (+11.85 Units / 46% ROI)
• Alex Bregman has hit the Singles Over in 13 of his last 15 games (+10.85 Units / 66% ROI)
• Nico Hoerner has hit the Runs Under in 19 of his last 25 away games (+10.70 Units / 29% ROI)
• Nico Hoerner has hit the Hits Under in 19 of his last 25 games (+10.60 Units / 21% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Saturday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• Ivan Herrera has hit the Home Runs Over in 3 of his last 4 games at home (+21.40 Units / 535% ROI)
• Alec Burleson has hit the Runs Under in 20 of his last 25 games at home (+11.50 Units / 27% ROI)
• Ivan Herrera has hit the Total Bases Over in 10 of his last 15 games at home (+8.30 Units / 52% ROI)
• Victor Scott II has hit the Singles Under in 12 of his last 15 games (+7.20 Units / 27% ROI)
• Ivan Herrera has hit the Hits Over in 18 of his last 25 games at home (+7.10 Units / 14% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have hit the Game Total Over in 30 of their last 50 games (+9.45 Units / 17% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 19 games (+8.95 Units / 39% ROI)
• The Chicago Cubs have hit the Team Total Under in 13 of their last 19 games (+5.55 Units / 23% ROI)
• The Chicago Cubs have hit the Moneyline in 25 of their last 45 games (+2.50 Units / 4% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Moneyline in 25 of their last 45 games (+8.60 Units / 19% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 15 of their last 23 games (+8.45 Units / 33% ROI)
• The St. Louis Cardinals have covered the Run Line in 26 of their last 40 games (+6.55 Units / 11% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 16 of their last 24 games at home (+6.40 Units / 22% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 19 of their last 40 games (+5.90 Units / 14% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 23-35 against the Run Line (-13.6 Units / -19.72% ROI).

• 31-27 when betting on the Moneyline for -2.4 Units / -3.07% ROI
• 33-24 when betting on the total runs Over for +7.2 Units / 11.3% ROI
• 24-33 when betting on the total runs Under for -12.05 Units / -18.8% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 33-21 against the Run Line (+3.9 Units / 4.83% ROI).

• 30-25 when betting on the Moneyline for +9.55 Units / 16.89% ROI
• 24-28 when betting on the total runs Over for -6.8 Units / -11.26% ROI
• 28-24 when betting on the total runs Under for +1.4 Units / 2.31% ROI

Cardinals vs Cubs Home Run Prop Bets Today

Cardinals vs Cubs Total Hits Prop Bets Today

Cardinals vs Cubs Strikeout Prop Bets Today

Cubs Keys to the Game vs. the Cardinals

The Cubs are 23-0 (1.000) when leading entering the 7th inning this season — tied for best in MLB; League Avg: .860.

The Cubs are 25-0 (1.000) when leading entering the 8th inning this season — tied for best in MLB; League Avg: .895.

The Cubs are 10-0 (1.000) when they’ve had 5 or more XBH this season — tied for best in MLB; League Avg: .792.

The Cubs are 9-2 (.818) when they’ve scored in the first inning this season — 2nd best in MLB; League Avg: .645.

Cardinals Keys to the Game vs. the Cubs

The Cardinals are 3-22 (.120) when trailing entering the 9th inning this season — tied for 3rd best in MLB; League Avg: .054.

The Cardinals are 17-11 (.607) vs top 10 scoring offenses this season Today, they face the Cubs (seventh in runs scored).

The Cardinals are just 9-88 (.093) when trailing entering the 7th inning since the 2025 season — 5th lowest in MLB; League Avg: .128.

The Cardinals are 31-19 (.620) when tied entering the 7th inning since the 2024 season — 2nd best in MLB; League Avg: .499.

Cubs Hitting Stats & Trends

Cubs hitters have drawn walks in 14% of their PA’s when leading off an inning this season — best in MLB.

Cubs hitters have drawn walks in 12% of their PA’s against RHP this season — best in MLB.

Cubs hitters have an OBP of .344 (644 PA’s) against LHP this season — 2nd best in MLB.

Cubs hitters have a swing rate of just 44% this season — 2nd lowest in MLB.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 17% of their PA’s against LHP this season — best in MLB.

Cardinals hitters are slugging .274 with two-strikes this season — 5th best in MLB.

Cardinals hitters have struck out in just 16% of their PA’s in lefty-lefty matchups this season — best in MLB.

The Cardinals are batting just .211 with two outs this season — 5th lowest in MLB.

Cubs Pitching Stats & Trends

Opponents have a groundball batting average of just .194 against Cubs pitchers with runners on base this season — best in MLB.

The Cubs pitchers have allowed an average Exit Velocity of 90.1 MPH this season (1,442 balls in play) — tied for highest in MLB

Cubs pitchers have a strikeout rate of just 17% when facing the leadoff batter in the inning this season — tied for lowest in MLB.

Cubs pitchers have allowed an average Exit Velocity of 90.1 MPH (1,442 batted balls) this season — tied for highest in MLB.

Cardinals Pitching Stats & Trends

Cardinals pitchers have a strikeout rate of just 16% with runners in scoring position this season — lowest in MLB.

Opponents have a miss rate of just 23% against Cardinals pitchers this season — 3rd lowest in MLB.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes this season — 3rd lowest in MLB.

Cardinals pitchers have a strikeout rate of just 20% this season — 5th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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