• The Cubs are -110 favorites vs the Diamondbacks
• Cubs vs Diamondbacks Over / Under today: 8.5 Runs
• Cubs / Diamondbacks TV Channel: MARQ | DBTV

The Chicago Cubs (-110) visit Chase Field to take on the Arizona Diamondbacks (-110) on August 26, 2026. First pitch is scheduled for 3:40 pm in Phoenix, AZ.

This season, the Cubs are against the spread (ATS), while the Diamondbacks are ATS.

Cubs vs Diamondbacks Starting Pitchers Today:

• Cubs starting pitcher: Matthew Boyd 8-2, 4.20 ERA
• Diamondbacks starting pitcher: Eduardo Rodriguez 13-4, 2.61 ERA

Cubs vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

Cubs vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Wednesday‘s MLB game with 54.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Cubs vs Diamondbacks and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

• Tyrone Taylor has hit the Home Runs Over in 3 of his last 7 away games (+20.50 Units / 293% ROI)
• Pete Crow-Armstrong has hit the Singles Under in 20 of his last 25 away games (+13.10 Units / 39% ROI)
• Tyrone Taylor has hit the Runs Over in 11 of his last 20 games (+10.20 Units / 51% ROI)
• Seiya Suzuki has hit the RBIs Over in 13 of his last 25 away games (+9.90 Units / 40% ROI)
• Seiya Suzuki has hit the Hits Over in 19 of his last 25 games (+9.05 Units / 18% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Wednesday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

• Eduardo Rodriguez has hit the Earned Runs Under in 20 of his last 25 games (+15.10 Units / 52% ROI)
• Gabriel Moreno has hit the Total Bases Over in 14 of his last 20 games (+12.00 Units / 60% ROI)
• Jordan Lawlar has hit the Home Runs Over in 2 of his last 8 games at home (+10.50 Units / 131% ROI)
• Corbin Carroll has hit the Singles Under in 19 of his last 25 games at home (+10.45 Units / 29% ROI)
• Gabriel Moreno has hit the RBIs Over in 7 of his last 10 games (+8.55 Units / 86% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have covered the Run Line in 25 of their last 35 away games (+18.75 Units / 44% ROI)
• The Chicago Cubs have hit the Team Total Over in 25 of their last 35 away games (+13.55 Units / 32% ROI)
• The Chicago Cubs have hit the Moneyline in 24 of their last 35 away games (+12.45 Units / 30% ROI)
• The Chicago Cubs have hit the Game Total Over in 12 of their last 17 away games (+7.60 Units / 41% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 22 of their last 35 away games (+7.15 Units / 16% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the Moneyline in 29 of their last 50 games (+11.15 Units / 19% ROI)
• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 30 of their last 50 games at home (+6.60 Units / 11% ROI)
• The Arizona Diamondbacks have hit the Team Total Over in 30 of their last 50 games (+6.55 Units / 11% ROI)
• The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 18 of their last 30 games at home (+5.15 Units / 15% ROI)
• The Arizona Diamondbacks have hit the Game Total Under in 27 of their last 50 games at home (+5.05 Units / 9% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Diamondbacks vs Cubs Home Run Prop Bets Today

Diamondbacks vs Cubs Total Hits Prop Bets Today

Diamondbacks vs Cubs Strikeout Prop Bets Today

Cubs Keys to the Game vs. the Diamondbacks

The Cubs are 18-22 (.450) when allowing 10 or more hits this season — best in MLB.

The Cubs are 6-51 (.105) when trailing entering the 9th inning this season — best in MLB.

The Cubs are 28-29 (.491) when allowing 2 or more home runs this season — best in MLB.

The Cubs are 41-5 (.891) when they’ve had 10 or more hits this season — tied for best in MLB.

Diamondbacks Keys to the Game vs. the Cubs

The Diamondbacks are 60-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB.

The Diamondbacks are 10-46 (.179) when trailing entering the 7th inning this season — 4th best in MLB.

The Diamondbacks are 9-119 (.070) when trailing entering the 9th inning since the 2025 season — 2nd best in MLB.

The Diamondbacks are just 110-25 (.815) when leading entering the 7th inning since the 2025 season — 4th lowest in MLB.

Cubs Hitting Stats & Trends

Cubs hitters have an OBP of .356 (1,382 PA’s) against LHP this season — best in MLB.

The Cubs are batting .269 against LHP this season — 2nd best in MLB.

Cubs hitters have an OPS of .809 (1,382 PA’s) against LHP this season — best in MLB.

Cubs hitters have drawn walks in 11% of their PA’s this season — tied for best in MLB.

Diamondbacks Hitting Stats & Trends

The Diamondbacks are batting .281 against LHP this season — best in MLB.

Diamondbacks hitters have struck out in just 18% of their PA’s against LHP this season — best in MLB.

Diamondbacks hitters are slugging .452 against LHP this season — tied for best in MLB.

Diamondbacks hitters have a swing rate of just 25% on the first pitch of at-bats this season — lowest in MLB.

Cubs Pitching Stats & Trends

Opponents have a groundball batting average of just .205 against Cubs pitchers with runners on base this season — best in MLB.

Opponents have a groundball batting average of just .218 against Cubs pitchers this season — best in MLB.

Cubs pitchers have picked-off 21 runners from first base this season — most in MLB.

In games when their opponents have scored three or more runs in an inning, the Cubs have still managed to win 37% of the time this season — highest in MLB.

Diamondbacks Pitching Stats & Trends

Diamondbacks pitchers have a strikeout rate of just 18% this season — 2nd lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 38% with two-strikes this season — tied for 2nd lowest in MLB.

Diamondbacks pitchers have struck out just 17% of left-handed batters they faced this season — 2nd lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 17% in the first 5 innings this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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