- The Cubs are -120 favorites vs the Guardians
- Cubs vs Guardians Over / Under today: 7.5 Runs
- Cubs / Guardians TV Channel: GDTV | WKYC | MARQ | ESUN
The Chicago Cubs (-120) visit Progressive Field to take on the Cleveland Guardians (+100) on April 3, 2026. First pitch is scheduled for 4:10 pm in Cleveland, OH.
This season, the Cubs are against the spread (ATS), while the Guardians are ATS.
Cubs vs Guardians Starting Pitchers Today:
- Cubs starting pitcher: Cade Horton 1-0, 2.84 ERA
- Guardians starting pitcher: Joey Cantillo 0-0, 4.91 ERA
Cubs vs. Guardians Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Cubs | -1.5 +145 | O 7.5 -115 | -120 |
| Guardians | +1.5 -175 | U 7.5 -105 | +100 |
Cubs vs Guardians Prediction for Today’s Game
Based on recent trends the model predicts the Cubs will win Friday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
Bet now on Cubs vs Guardians and all games with BetMGM
We’ve highlighted some favorite MLB player prop bets for Cubs players for Friday‘s game, looking at profitable historical betting trends:
Best Cubs Player Prop Bets Today:
- Ian Happ has hit the Singles Under in 17 of his last 20 games (+12.55 Units / 38% ROI)
- Michael Busch has hit the Home Runs Over in 4 of his last 8 away games (+12.25 Units / 153% ROI)
- Cade Horton has hit the Earned Runs Under in 13 of his last 15 games (+11.75 Units / 60% ROI)
- Michael Busch has hit the Walks Over in 14 of his last 25 games (+10.95 Units / 44% ROI)
- Pete Crow-Armstrong has hit the Runs Under in 19 of his last 25 away games (+9.75 Units / 24% ROI)
And here are some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:
Best Guardians Player Prop Best Bets Today:
- Brayan Rocchio has hit the Home Runs Over in 2 of his last 4 games at home (+21.00 Units / 525% ROI)
- Kyle Manzardo has hit the Total Bases Under in 17 of his last 25 games (+10.30 Units / 33% ROI)
- Steven Kwan has hit the Hits Under in 10 of his last 15 games (+9.85 Units / 51% ROI)
- Kyle Manzardo has hit the Hits Runs and RBIs Under in 17 of his last 25 games (+8.95 Units / 31% ROI)
- Steven Kwan has hit the Singles Under in 10 of his last 15 games at home (+7.25 Units / 48% ROI)
Cubs Best Bets Today:
- The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 81 of their last 161 games (+14.70 Units / 6% ROI)
- The Chicago Cubs have hit the Game Total Under in 64 of their last 117 games (+13.65 Units / 11% ROI)
- The Chicago Cubs have hit the Team Total Under in 20 of their last 26 away games (+13.15 Units / 42% ROI)
- The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 30 of their last 46 games (+11.35 Units / 20% ROI)
- The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 27 of their last 46 games (+5.45 Units / 10% ROI)
Guardians Best Bets Today:
- The Cleveland Guardians have hit the Moneyline in 49 of their last 77 games (+21.25 Units / 23% ROI)
- The Cleveland Guardians have hit the Game Total Under in 72 of their last 128 games (+17.40 Units / 12% ROI)
- The Cleveland Guardians have covered the Run Line in 47 of their last 82 games (+13.00 Units / 12% ROI)
- The Cleveland Guardians have hit the Team Total Under in 45 of their last 77 games at home (+9.59 Units / 11% ROI)
- The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 44 of their last 78 games (+8.55 Units / 10% ROI)
Cubs Against the Spread (ATS) Record
Against the spread this season, the Cubs are against the Run Line ( Units / ROI).
- away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
- away total over record when betting on the total runs Over for over units Units / over ROI ROI
- away total under record when betting on the total runs Under for under units Units / under ROI ROI
Guardians Against the Spread (ATS) Record
Against the spread this season, the Guardians are against the Run Line ( Units / ROI).
- home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
- home total over record when betting on the total runs Over for over units Units / over ROI ROI
- home total under record when betting on the total runs Under for under units Units / under ROI ROI
Cubs Keys to the Game vs. the Guardians
The Cubs were 48-6 (.889) when they had 10 or more hits in the 2025 season — best in MLB; League Avg: .743.
The Cubs were 40-9 (.816) when they scored in the first inning in the 2025 season — best in MLB; League Avg: .636.
The Cubs are 73-19 (.793) when they’ve scored in the first inning since the 2024 season — best in MLB; League Avg: .640.
The Cubs were 42-39 (.519) on the road in the 2025 season — 4th best in MLB; League Avg: .457.
Guardians Keys to the Game vs. the Cubs
The Guardians were 24-2 (.923) when they had 5 or more XBH in the 2025 season — 2nd best in MLB; League Avg: .799.
The Guardians were 33-4 (.868) when they had 10 or more hits in the 2025 season — 2nd best in MLB; League Avg: .743.
The Guardians are 139-7 (.952) when leading entering the 7th inning since the 2024 season — best in MLB; League Avg: .866.
The Guardians were just 73-5 (.936) when leading entering the 9th inning in the 2025 season — 5th lowest in MLB; League Avg: .956.
Cubs Hitting Stats & Trends
Cubs hitters have a swing rate of just 39% in righty-righty matchups this season — lowest in MLB.
Cubs hitters have struck out in just 19% of their PA’s against RHP this season — 5th best in MLB.
Cubs hitters have struck out in just 11% of their PA’s in righty-righty matchups this season — best in MLB.
Cubs hitters struck out in just 20% of their PA’s against RHP in the 2025 season — 5th best in MLB.
Guardians Hitting Stats & Trends
The Guardians are batting just .224 since the 2025 season — tied for lowest in MLB.
The Guardians batted just .226 in the 2025 season — 2nd lowest in MLB.
The Guardians batted just .186 in righty-righty matchups in the 2025 season — lowest in MLB.
Guardians hitters had an OPS of just .647 (1,784 PA’s) against LHP in the 2025 season — 4th lowest in MLB.
Cubs Pitching Stats & Trends
Cubs pitchers walked 7% of batters in the 2025 season — best in MLB.
Cubs pitchers have walked 7% of batters since the 2025 season — best in MLB.
Cubs pitchers picked-off 25 runners from first base in the 2025 season — most in MLB.
Opponents have a miss rate of 33% against Cubs pitchers this season — 4th best in MLB.
Guardians Pitching Stats & Trends
Opponents had a chase percentage of just 26% against the Guardians pitchers in the 2025 season — lowest in MLB.
Guardians pitchers had an ERA of 2.54 (471.1 IP) against division opponents in the 2025 season — best in MLB.
Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.
Opponents had a groundball batting average of just .223 against Guardians pitchers in the 2024 season — best in MLB; League Avg: .249.
More MLB Reading:
Bet now on Cubs vs Guardians and all games with BetMGM
Bet on MLB Odds at BetMGM
Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.
The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.
