Cubs vs Mariners Prediction, Odds & Player Prop Bets Today – MLB, Aug 22

Seattle Mariners' Julio Rodriguez reacts after the umpires confirmed a challenged call, ruling him out for fan interference on a foul ball during the eighth inning of the team's baseball game against the Oakland Athletics, Tuesday, May 23, 2023, in Seattle.
(AP Photo/Caean Couto)
Parlay Boost Today
  • The Mariners are -120 favorites vs the Cubs
  • Cubs vs Mariners Over / Under today: 7.5 Runs
  • Cubs / Mariners TV Channel: FOX

The Chicago Cubs (+100) visit T-Mobile Park to take on the Seattle Mariners (-120) on August 22, 2026. First pitch is scheduled for 7:15 pm in Seattle, WA.

This season, the Cubs are 74-55 against the spread (ATS), while the Mariners are 49-79 ATS.

Cubs vs Mariners Starting Pitchers Today:

  • Cubs starting pitcher: David Peterson 7-7, 5.31 ERA
  • Mariners starting pitcher: Kade Anderson 0-0, 0.00 ERA

Cubs vs. Mariners Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cubs+1.5 -220O 7.5 -110+100
Mariners -1.5 +165U 7.5 -110-120

Cubs vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Saturday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cubs players for Saturday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

  • Tyrone Taylor has hit the Home Runs Over in 3 of his last 6 away games (+21.50 Units / 358% ROI)
  • Pete Crow-Armstrong has hit the Singles Under in 20 of his last 25 games (+12.60 Units / 38% ROI)
  • Pete Crow-Armstrong has hit the RBIs Over in 10 of his last 15 away games (+11.05 Units / 74% ROI)
  • Michael Busch has hit the Walks Under in 13 of his last 15 away games (+9.30 Units / 34% ROI)
  • Pete Crow-Armstrong has hit the Hits Under in 11 of his last 15 games (+8.40 Units / 31% ROI)

And here are some favorite MLB player prop bets for Mariners players for Saturday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

  • Cal Raleigh has hit the Runs Under in 21 of his last 25 games (+13.55 Units / 31% ROI)
  • Dominic Canzone has hit the RBIs Under in his last 10 games at home (+10.00 Units / 41% ROI)
  • Cal Raleigh has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+9.90 Units / 29% ROI)
  • Randy Arozarena has hit the Home Runs Over in 3 of his last 10 games (+9.50 Units / 95% ROI)
  • Cal Raleigh has hit the Total Bases Under in 17 of his last 25 games at home (+9.45 Units / 33% ROI)
  • The Chicago Cubs have covered the Run Line in 30 of their last 50 games (+16.25 Units / 28% ROI)
  • The Chicago Cubs have hit the Moneyline in 21 of their last 30 away games (+11.55 Units / 32% ROI)
  • The Chicago Cubs have hit the Team Total Over in 21 of their last 30 away games (+10.50 Units / 29% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 19 of their last 30 away games (+6.40 Units / 17% ROI)
  • The Chicago Cubs have hit the Game Total Over in 9 of their last 13 away games (+5.70 Units / 40% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Under in 28 of their last 45 games at home (+9.70 Units / 18% ROI)
  • The Seattle Mariners have hit the Game Total Over in 26 of their last 45 games (+9.45 Units / 19% ROI)
  • The Seattle Mariners have hit the Team Total Under in 27 of their last 45 games at home (+8.85 Units / 18% ROI)
  • The Seattle Mariners have covered the 1st Five Innings (F5) Run Line in 7 of their last 10 games (+3.55 Units / 29% ROI)
  • The Seattle Mariners have hit the Moneyline in 5 of their last 8 games (+2.60 Units / 32% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 61-66 against the Run Line (-1.45 Units / -0.96% ROI).

  • 74-55 when betting on the Moneyline for +3.75 Units / 2.15% ROI
  • 69-58 when betting on the total runs Over for +5.9 Units / 4.15% ROI
  • 58-69 when betting on the total runs Under for -17.35 Units / -12.22% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 49-79 against the Run Line (-26.2 Units / -17.68% ROI).

  • 61-68 when betting on the Moneyline for -23.1 Units / -13.49% ROI
  • 65-57 when betting on the total runs Over for +2.5 Units / 1.76% ROI
  • 57-65 when betting on the total runs Under for -14.2 Units / -10.02% ROI

Mariners vs Cubs Home Run Prop Bets Today

Yes
Pete Crow-Armstrong +310
Seiya Suzuki +350
Randy Arozarena +375
Julio Rodriguez +375
Cal Raleigh +400

Mariners vs Cubs Total Hits Prop Bets Today

Over Under
Randy Arozarena 0.5 -235 0.5 +175
Julio Rodriguez 0.5 -225 0.5 +165
Nico Hoerner 0.5 -220 0.5 +160
Brendan Donovan 0.5 -210 0.5 +155
Josh Naylor 0.5 -190 0.5 +140

Mariners vs Cubs Strikeout Prop Bets Today

Over Under
Miguel Amaya 0.5 -235 0.5 +175
Pedro Ramirez 0.5 -225 0.5 +165
Julio Rodriguez 0.5 -185 0.5 +135
Tyrone Taylor 0.5 -185 0.5 +135
Randy Arozarena 0.5 -175 0.5 +130

Cubs Keys to the Game vs. the Mariners

The Cubs are 18-22 (.450) when allowing 10 or more hits this season — best in MLB.

The Cubs are 6-51 (.105) when trailing entering the 9th inning this season — best in MLB.

The Cubs are 28-28 (.500) when allowing 2 or more home runs this season — best in MLB.

The Cubs are 33-2 (.943) when they’ve had 5 or more XBH this season — 2nd best in MLB.

Mariners Keys to the Game vs. the Cubs

The Mariners are just 1-58 (.017) when trailing entering the 8th inning this season — 2nd lowest in MLB.

The Mariners are just 17-20 (.459) when they’ve scored in the first inning this season — tied for lowest in MLB.

The Mariners are just 13-30 (.302) vs the top 10 runs allowed teams this season Today, they face Cubs (12th fewest runs allowed).

The Mariners are just 1-61 (.016) when trailing entering the 9th inning this season — tied for lowest in MLB.

The Cubs are batting .268 against LHP this season — 2nd best in MLB.

Cubs hitters have an OBP of .356 (1,353 PA’s) against LHP this season — best in MLB.

Cubs hitters have drawn walks in 11% of their PA’s this season — tied for best in MLB.

Cubs hitters have an OPS of .805 (1,353 PA’s) against LHP this season — best in MLB.

Mariners hitters are slugging just .479 on the first pitch of at-bats this season — lowest in MLB.

The Mariners are batting just .216 against LHP this season — lowest in MLB.

The Mariners are batting just .150 with two-strikes this season — tied for 2nd lowest in MLB.

Mariners hitters have an OPS of just .684 (4,822 PA’s) this season — 2nd lowest in MLB.

Opponents have a groundball batting average of just .205 against Cubs pitchers with runners on base this season — best in MLB.

In games when their opponents have scored three or more runs in an inning, the Cubs have still managed to win 38% of the time this season — highest in MLB.

Cubs pitchers have picked-off 20 runners from first base this season — most in MLB.

Cubs pitchers have picked-off 20 runners this season — most in MLB.

Mariners pitchers have a first-pitch strike rate of 66% this season — highest in MLB.

Mariners pitchers have walked 7% of batters this season — tied for best in MLB.

Mariners pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — best in MLB.

The Mariners pitchers have allowed their opponents to score first in just 41% of their games at home this season — 2nd lowest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.