Cubs vs Marlins Prediction, Odds & Player Prop Bets Today – MLB, Sep 21

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Sep 21, 2022, 3:30 PM
  • The Cubs (63-85) are -110 favorites vs the Marlins (61-88)
  • Cubs starting pitcher: Marcus Stroman (4-7), 3.76 ERA
  • Marlins starting pitcher: Jesús Luzardo (3-7), 3.74 ERA
  • Watch the game on BSFL

The Chicago Cubs (-110) visit loanDepot park to take on the Miami Marlins (-110) on Wednesday, September 21, 2022. First pitch is scheduled for 6:40pm EDT in Miami.

The Cubs are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+165).

The Cubs vs Marlins Over/Under is 6.5 total runs for the game.

So far this season, the Cubs are 62-84 against the spread (ATS), while the Marlins are 69-78 ATS.

Cubs vs. Marlins Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cubs-1.5 +165O 6.5 +100-110
Marlins +1.5 -200U 6.5 -120-110

Cubs vs Marlins Prediction for Today’s Game

Based on recent trends the model predicts the Marlins will win Wednesday‘s matchup with 53.7% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cubs and Marlins and up-to-date player injuries.


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Best Cubs Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:

  • Frank Schwindel has hit the Runs Under in 18 of his last 19 away games (+16.10 Units / 42% ROI)
  • Nico Hoerner has hit the Singles Under in 20 of his last 29 away games (+13.35 Units / 45% ROI)
  • Seiya Suzuki has hit the Hits Over in 16 of his last 19 games (+10.75 Units / 27% ROI)
  • Nico Hoerner has hit the Hits Under in 17 of his last 24 away games (+10.25 Units / 24% ROI)
  • Marcus Stroman has hit the Earned Runs Under in 10 of his last 11 away games (+8.25 Units / 56% ROI)

Best Marlins Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Marlins players for Wednesday‘s game, looking at profitable historical betting trends:

  • Sandy Alcantara has hit the Earned Runs Under in 20 of his last 28 games (+11.50 Units / 30% ROI)
  • Garrett Cooper has hit the Singles Under in 17 of his last 22 games at home (+10.35 Units / 34% ROI)
  • Sandy Alcantara has hit the Pitching Outs Over in 16 of his last 21 games (+9.05 Units / 31% ROI)
  • JJ Bleday has hit the Singles Under in 13 of his last 15 games at home (+8.35 Units / 25% ROI)
  • Trevor Rogers has hit the Earned Runs Over in 10 of his last 12 games (+8.10 Units / 54% ROI)

Marlins vs Cubs Home Run Prop Bets Today

Over Under
Bryan De La Cruz 0.5 +550 0.5 -1400
Garrett Cooper 0.5 +575 0.5 -1400
JJ Bleday 0.5 +550 0.5 -1400
Jon Berti 0.5 +875 0.5 -5000
Lewin Diaz 0.5 +700 0.5 -2500

Marlins vs Cubs Total Hits Prop Bets Today

Over Under
Bryan De La Cruz 0.5 -200 0.5 +140
Garrett Cooper 0.5 -200 0.5 +140
JJ Bleday 0.5 -160 0.5 +115
Jon Berti 0.5 -275 0.5 +190
Lewin Diaz 0.5 -110 0.5 -125

Marlins vs Cubs RBI Prop Bets Today

Over Under
Bryan De La Cruz 0.5 +185 0.5 -275
Garrett Cooper 0.5 +170 0.5 -250
JJ Bleday 0.5 +195 0.5 -300
Jon Berti 0.5 +250 0.5 -375
Lewin Diaz 0.5 +260 0.5 -400

Marlins vs Cubs Strikeout Prop Bets Today

Over Under
Jesus Luzardo 7.5 -110 7.5 -125
Marcus Stroman 4.5 -120 4.5 -115
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 36 of their last 62 away games (+11.45 Units / 17% ROI)
  • The Chicago Cubs have hit the Moneyline in 4 of their last 5 away games (+8.30 Units / 166% ROI)
  • The Chicago Cubs have hit the Game Total Under in 10 of their last 12 games (+7.70 Units / 59% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Total Under in 23 of their last 41 away games (+6.35 Units / 14% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 7 of their last 12 games (+5.20 Units / 39% ROI)
  • The Miami Marlins have covered the 1st Five Innings (F5) Run Line in 15 of their last 20 games at home (+9.85 Units / 41% ROI)
  • The Miami Marlins have hit the 1st Five Innings (F5) Moneyline in their last 7 games at home (+7.05 Units / 82% ROI)
  • The Miami Marlins have hit the Game Total Under in 22 of their last 40 games at home (+5.35 Units / 12% ROI)
  • The Miami Marlins have hit the 1st Five Innings (F5) Total Under in 22 of their last 40 games at home (+4.75 Units / 10% ROI)
  • The Miami Marlins have covered the Run Line in 9 of their last 16 games (+1.40 Units / 7% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this MLB season, the Cubs have gone 72-73 against the Run Line (-12.15 Units / -6.56% ROI).

  • 62-84 when betting on the Moneyline for -14.3 Units / -8.62% ROI
  • 59-75 when betting on the total runs Over for -23.35 Units / -14.65% ROI
  • 75-59 when betting on the total runs Under for +10.1 Units / 6.3% ROI

Marlins Against the Spread (ATS) Record

Against the spread this MLB season, the Cubs have gone 69-78 against the Run Line (-20.5 Units / -10.56% ROI).

  • 61-86 when betting on the Moneyline for -29.55 Units / -16.97% ROI
  • 65-75 when betting on the total runs Over for -17.3 Units / -10.63% ROI
  • 75-65 when betting on the total runs Under for +3.75 Units / 2.32% ROI

Opposing hitters have a groundball rate of 60% (47/78) against Marcus Stroman when he’s behind in the count this season — 4th highest in MLB among starting pitchers with at least 73 total IP; League Avg: 40% — 97th Percentile.

Left-handed hitters have a groundball rate of 55% (247/451) against Marcus Stroman since the start of last season — 3rd highest in MLB among starting pitchers with at least 154 total IP; League Avg: 44% — 97th Percentile.

Marcus Stroman has thrown his curveball 37% of the time (840/2,263) against right-handed batters since the start of last season — 4th highest in MLB among starting pitchers with at least 154 total CB; League Avg: 15% — 97th Percentile.

Left-handed hitters have a groundball rate of 52% (13/25) against Marcus Stroman this month (3 games) — tied for 10th highest among qualified SPs in MLB; League Avg: 42% — 83rd Percentile.

Jesús Luzardo: Marlins Starting Pitcher Stats & Trends

Opponents have a chase percentage of just 29% (78/265) against Jesus Luzardo with two-strikes this season — lowest in MLB among starting pitchers with at least 73 total IP; League Avg: 41% — 0 Percentile.

Jesus Luzardo has allowed a slugging percentage of .816 (40 Total Bases / 49 ABs) in late innings since the start of last season — highest in MLB among starting pitchers with at least 154 total IP; League Avg: .397 — first Percentile.

Opponents have a groundball rate of just 24% (10/42) against Jesus Luzardo this month (3 games) — 4th lowest among qualified SPs in MLB; League Avg: 42% — fourth Percentile.

Jesus Luzardo has allowed an OPS of 1.237 (58 PA’s) in late innings since the start of last season — highest in MLB among starting pitchers with at least 154 total IP; League Avg: .696 — first Percentile.

Cubs Keys to the Game vs. the Marlins

The Cubs are just 8-41 (.163) when allowing 10 or more hits this season — 5th lowest in MLB; League Avg: .277.

The Cubs are just 18-106 (.145) when allowing 10 or more hits since the 2020 season — lowest in MLB; League Avg: .267.

The Cubs are just 62-71 (.466) when allowing 5 or more extra base hits this season — 10th lowest in MLB; League Avg: .534.

The Cubs are just 10-14 (.417) when tied entering the 7th inning this season — 10th lowest in MLB; League Avg: .500.

Marlins Keys to the Game vs. the Cubs

The Marlins are just 25-83 (.231) when scoring 4 or fewer runs this season — 6th lowest in MLB; League Avg: .295.

The Marlins are just 8-12 (.400) when tied entering the 7th inning this season — tied for 7th lowest in MLB; League Avg: .500.

The Marlins are just 46-12 (.793) when leading entering the 7th inning this season — 4th lowest in MLB; League Avg: .881.

The Marlins are just 8-51 (.136) when allowing 5 or more runs this season — tied for 6th lowest in MLB; League Avg: .199.

Cubs hitters have grounded into 52 double plays in 372 opportunities (14%) in close and late situations since the start of last season — highest in MLB; League Avg: 9%.

The Cubs are batting .372 on the first pitch of at-bats this season — best in MLB; League Avg: .336.

Cubs hitters have put just 32% of their swings in play on the first pitch of at-bats this season — lowest in MLB; League Avg: 35%.

Cubs hitters are slugging just .173 in lefty-lefty matchups this season — lowest in MLB; League Avg: .349.

Marlins hitters have an OBP of just .284 (2,933 PA’s) against LHP since the start of last season — lowest in MLB; League Avg: .318.

Marlins hitters have 808 strikeouts in 2,933 PA’s (28%) against LHP since the start of last season — highest in MLB; League Avg: 22%.

The Marlins are batting just .209 against LHP this season — lowest in MLB; League Avg: .245.

Marlins hitters are slugging just .329 against LHP this season — lowest in MLB; League Avg: .400.

Cubs pitchers have walked 1,093 of 11,864 batters (9%) since the start of last season — 5th highest in MLB; League Avg: 8%.

Opponents have a groundball rate of 53% against Cubs pitchers over the past seven days (6 games) — highest in MLB; League Avg: 43%.

Cubs pitchers have won only 19% of games in which they have allowed their opponent to score in three different innings at home since the start of last season — tied for 2nd lowest in MLB; League Avg: 29%.

Cubs pitchers have a strikeout rate of just 15% when going through the lineup the third time in a game since the start of last season — 2nd lowest in MLB; League Avg: 19%.

Opponents have a groundball rate of 45% against Marlins pitchers since the start of last season — 4th highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 45% against Marlins pitchers this season — 4th highest in MLB; League Avg: 43%.

In games when their opponents have scored three or more runs in an inning, the Marlins have won just just 17% of the time since the start of last season — 2nd lowest in MLB; League Avg: 24%.

Marlins pitchers have won only 13% of games in which they have allowed their opponent to score in three different innings at home this season — lowest in MLB; League Avg: 27%.

Marlins vs. Cubs Injuries Tonight That May Affect Prop Bets 

  • Jorge Soler (Marlins): Back, D60
  • Max Meyer (Marlins): Elbow, D60
  • Trevor Rogers (Marlins): Lat, Day-to-Day
  • Paul Campbell (Marlins): Elbow, D60
  • Daniel Castano (Marlins): Concussion, D7
  • Sean Guenther (Marlins): Arm, D60
  • Avisaíl García (Marlins): Hamstring, D10
  • Cody Poteet (Marlins): Elbow, D60
  • Thomas Nance (Marlins): Groin, D15
  • Jordan Holloway (Marlins): Elbow, D60
  • Jasrado Chisholm Jr. (Marlins): Back, D60
  • Anthony Bender (Marlins): Elbow, D60
  • Todd Smyly (Cubs): Shoulder, Day-to-Day
  • Nicholas Hoerner (Cubs): Triceps, Day-to-Day
  • Kyle Hendricks (Cubs): Shoulder, D60
  • Nicklaus Madrigal (Cubs): Groin, D10
  • Bradley Wieck (Cubs): Elbow, D60
  • Codi Heuer (Cubs): Elbow, D60
  • Steven Brault (Cubs): Shoulder, D15
  • Keegan Thompson (Cubs): Back, D15
  • Willson Contreras (Cubs): Foot, D10
  • Rafael Ortega (Cubs): Finger, D60
  • Justin Steele (Cubs): Undisclosed, D15
  • Alec Mills (Cubs): Back, D60
  • Ethan Roberts (Cubs): Shoulder, D60
  • Jason Heyward (Cubs): Knee, D60

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.