• The Cubs are -165 favorites vs the Nationals
• Cubs vs Nationals Over / Under today: 9.5 Runs
• Cubs / Nationals TV Channel: MARQ | NATV | WTTG

The Chicago Cubs (-165) visit Nationals Park to take on the Washington Nationals (+135) on August 12, 2026. First pitch is scheduled for 6:45 pm in Washington, D.C., DC.

This season, the Cubs are 70-50 against the spread (ATS), while the Nationals are 70-49 ATS.

Cubs vs Nationals Starting Pitchers Today:

• Cubs starting pitcher: David Peterson 6-7, 5.39 ERA
• Nationals starting pitcher: Miles Mikolas 3-9, 5.86 ERA

Cubs vs. Nationals Odds, Run Line, Over/Under & Moneyline

Cubs vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Wednesday‘s MLB game with 58.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

• Nico Hoerner has hit the Home Runs Over in 2 of his last 10 games (+20.00 Units / 200% ROI)
• Seiya Suzuki has hit the Hits Runs and RBIs Over in 19 of his last 25 games (+12.50 Units / 41% ROI)
• Pete Crow-Armstrong has hit the Singles Under in 16 of his last 20 away games (+10.60 Units / 39% ROI)
• Alex Bregman has hit the Hits Over in 13 of his last 15 games (+9.80 Units / 33% ROI)
• Alex Bregman has hit the Runs Over in 15 of his last 25 games (+9.50 Units / 38% ROI)

And here are some favorite MLB player prop bets for Nationals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

• CJ Abrams has hit the Hits Over in 21 of his last 25 games at home (+14.90 Units / 28% ROI)
• Dylan Crews has hit the Runs Over in 14 of his last 20 games at home (+11.20 Units / 56% ROI)
• Nasim Nunez has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+8.65 Units / 24% ROI)
• Daylen Lile has hit the Home Runs Over in 3 of his last 10 games (+8.50 Units / 85% ROI)
• Andres Chaparro has hit the Singles Under in 9 of his last 10 games (+7.40 Units / 42% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have covered the Run Line in 30 of their last 45 games (+22.35 Units / 42% ROI)
• The Chicago Cubs have hit the Moneyline in 31 of their last 45 games (+14.80 Units / 26% ROI)
• The Chicago Cubs have hit the Team Total Over in 30 of their last 45 games (+12.05 Units / 22% ROI)
• The Chicago Cubs have hit the Game Total Over in 26 of their last 45 games (+6.25 Units / 13% ROI)
• The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 7 of their last 8 away games (+6.10 Units / 64% ROI)

Nationals Best Bets Today:

• The Washington Nationals have hit the 1st Five Innings (F5) Moneyline in 27 of their last 45 games at home (+11.25 Units / 20% ROI)
• The Washington Nationals have covered the 1st Five Innings (F5) Run Line in 29 of their last 45 games at home (+10.85 Units / 21% ROI)
• The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 27 of their last 45 games at home (+6.60 Units / 13% ROI)
• The Washington Nationals have hit the Team Total Over in their last 6 games (+6.15 Units / 88% ROI)
• The Washington Nationals have hit the Game Total Under in 10 of their last 15 games at home (+5.50 Units / 33% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 58-60 against the Run Line (+1.15 Units / 0.81% ROI).

• 70-50 when betting on the Moneyline for +7.5 Units / 4.69% ROI
• 64-54 when betting on the total runs Over for +5.2 Units / 3.93% ROI
• 54-64 when betting on the total runs Under for -15.85 Units / -12.01% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 70-49 against the Run Line (+11.65 Units / 7.14% ROI).

• 59-62 when betting on the Moneyline for +7.25 Units / 5.6% ROI
• 65-50 when betting on the total runs Over for +10.75 Units / 8.09% ROI
• 50-65 when betting on the total runs Under for -21.3 Units / -15.96% ROI

Nationals vs Cubs Home Run Prop Bets Today

Nationals vs Cubs Total Hits Prop Bets Today

Nationals vs Cubs Strikeout Prop Bets Today

Cubs Keys to the Game vs. the Nationals

The Cubs are 5-1 (.833) this season — 2nd best in MLB.

The Cubs are 5-1 (.833) since the 2025 season — 2nd best in MLB.

The Cubs are 5-1 (.833) since the 2024 season — 2nd best in MLB.

The Cubs were 32-10 (.762) when they scored in the first inning in the 2024 season — 3rd best in MLB; League Avg: .641.

Nationals Keys to the Game vs. the Cubs

The Nationals were just 65-96 (.401) in the 2025 season — 3rd lowest in MLB; League Avg: .500.

The Nationals were just 11-43 (.200) when their opponents score in the first inning in the 2025 season — lowest in MLB; League Avg: .362.

The Nationals were just 55-3 (.932) when leading entering the 9th inning in the 2025 season — 4th lowest in MLB; League Avg: .956.

The Nationals were just 64-79 (.444) when allowing 5 or more extra base hits in the 2025 season — 3rd lowest in MLB; League Avg: .535.

Cubs Hitting Stats & Trends

Cubs hitters have an OBP of .357 (1,279 PA’s) against LHP this season — best in MLB.

The Cubs are batting .270 against LHP this season — 2nd best in MLB.

Cubs hitters have drawn walks in 11% of their PA’s this season — best in MLB.

Cubs hitters have an OBP of .369 (480 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Nationals Hitting Stats & Trends

Nationals hitters are slugging .438 against RHP this season — best in MLB.

Nationals hitters are slugging .441 this season — best in MLB.

Nationals hitters are slugging .433 on the road this season — 2nd best in MLB.

Nationals hitters are slugging .294 with two-strikes this season — 2nd best in MLB.

Cubs Pitching Stats & Trends

Cubs pitchers have won 38% of games in which they have allowed their opponent to score in three different innings this season — highest in MLB.

Opponents have a groundball batting average of just .210 against Cubs pitchers with runners on base this season — best in MLB.

The Cubs pitchers have allowed division opponents to score first in 64% of their games this season — 2nd highest in MLB.

In games when their opponents have scored three or more runs in an inning, the Cubs have still managed to win 39% of the time this season — highest in MLB.

Nationals Pitching Stats & Trends

Nationals pitchers have an ERA of 5.18 (556.0 IP) at home this season — 3rd highest in MLB.

Nationals pitchers have a strikeout rate of just 19% this season — 3rd lowest in MLB.

Opponents have a miss rate of just 22% against Nationals pitchers this season — lowest in MLB.

Nationals pitchers have a strikeout rate of just 37% with two-strikes this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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