• The Pirates are -135 favorites vs the Cubs
• Cubs vs Pirates Over / Under today: 7.5 Runs
• Cubs / Pirates TV Channel: MARQ | SNPT

The Chicago Cubs (+110) visit PNC Park to take on the Pittsburgh Pirates (-135) on July 25, 2026. First pitch is scheduled for 6:40 pm in Pittsburgh, PA.

This season, the Cubs are 58-45 against the spread (ATS), while the Pirates are 53-49 ATS.

Cubs vs Pirates Starting Pitchers Today:

• Cubs starting pitcher: Shota Imanaga 6-8, 3.92 ERA
• Pirates starting pitcher: Paul Skenes 9-8, 3.47 ERA

Cubs vs. Pirates Odds, Run Line, Over/Under & Moneyline

Cubs vs Pirates Prediction for Today’s Game

Based on recent trends the model predicts the Pirates will win Saturday‘s MLB game with 55.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Cubs vs Pirates and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Cubs players for Saturday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

• Carson Kelly has hit the Singles Under in 14 of his last 15 away games (+12.90 Units / 66% ROI)
• Seiya Suzuki has hit the Home Runs Over in 4 of his last 10 away games (+12.10 Units / 121% ROI)
• Seiya Suzuki has hit the Walks Under in 20 of his last 25 away games (+10.75 Units / 23% ROI)
• Alex Bregman has hit the Hits Under in 14 of his last 25 games (+9.05 Units / 31% ROI)
• Seiya Suzuki has hit the Runs Over in 16 of his last 25 games (+8.85 Units / 32% ROI)

And here are some favorite MLB player prop bets for Pirates players for Saturday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

• Esmerlyn Valdez has hit the Home Runs Over in 5 of his last 9 games at home (+21.00 Units / 233% ROI)
• Nick Gonzales has hit the Hits Over in 20 of his last 25 games (+13.85 Units / 28% ROI)
• Bryan Reynolds has hit the Runs Over in 17 of his last 25 games at home (+12.45 Units / 50% ROI)
• Esmerlyn Valdez has hit the RBIs Over in 12 of his last 20 games (+10.90 Units / 55% ROI)
• Nick Gonzales has hit the Singles Over in 19 of his last 25 games (+10.60 Units / 30% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have covered the Run Line in 21 of their last 35 games (+11.60 Units / 28% ROI)
• The Chicago Cubs have hit the Moneyline in 14 of their last 18 away games (+10.75 Units / 54% ROI)
• The Chicago Cubs have hit the Team Total Over in 30 of their last 50 away games (+7.75 Units / 13% ROI)
• The Chicago Cubs have hit the Game Total Under in 14 of their last 22 away games (+5.30 Units / 22% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 35 away games (+3.60 Units / 9% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have hit the Game Total Over in 33 of their last 50 games at home (+14.65 Units / 27% ROI)
• The Pittsburgh Pirates have hit the Team Total Over in 18 of their last 25 games (+10.05 Units / 34% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Over in 18 of their last 25 games (+10.00 Units / 33% ROI)
• The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 20 of their last 30 games (+8.65 Units / 24% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 6 of their last 8 games (+5.50 Units / 59% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 45-57 against the Run Line (-9.95 Units / -8.29% ROI).

• 58-45 when betting on the Moneyline for +1.15 Units / 0.83% ROI
• 54-48 when betting on the total runs Over for +1.8 Units / 1.58% ROI
• 48-54 when betting on the total runs Under for -10.85 Units / -9.58% ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 53-49 against the Run Line (+2.4 Units / 1.85% ROI).

• 53-51 when betting on the Moneyline for -6.1 Units / -4.7% ROI
• 59-42 when betting on the total runs Over for +12.95 Units / 11.32% ROI
• 42-59 when betting on the total runs Under for -22.7 Units / -19.84% ROI

Pirates vs Cubs Home Run Prop Bets Today

Pirates vs Cubs Total Hits Prop Bets Today

Pirates vs Cubs Strikeout Prop Bets Today

Cubs Keys to the Game vs. the Pirates

The Cubs are 25-12 (.676) vs bottom 10 scoring offenses this season Today, they face the Pirates (second in runs scored).

The Cubs are 23-1 (.958) when they’ve had 5 or more XBH this season — 2nd best in MLB; League Avg: .788.

The Cubs are 30-3 (.909) when they’ve had 10 or more hits this season — 2nd best in MLB; League Avg: .752.

The Cubs are 19-6 (.760) when they’ve scored in the first inning this season — 2nd best in MLB; League Avg: .629.

Pirates Keys to the Game vs. the Cubs

The Pirates are 41-11 (.788) when allowing 4 or fewer runs this season — 5th best in MLB; League Avg: .724.

The Pirates are just 4-26 (.133) when allowing 10 or more hits this season — 3rd lowest in MLB; League Avg: .248.

The Pirates are just 23-30 (.434) after a win this season — 4th lowest in MLB; League Avg: .514.

The Pirates are just 23-30 (.434) after a win since the 2025 season — 4th lowest in MLB; League Avg: .514.

Cubs Hitting Stats & Trends

Cubs hitters have an OBP of .355 (1,119 PA’s) against LHP this season — best in MLB.

Cubs hitters have an OBP of .355 (2,051 PA’s) at home this season — tied for best in MLB.

Cubs hitters have an OBP of .368 (399 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Cubs hitters have an OBP of .337 (4,060 PA’s) this season — 3rd best in MLB.

Pirates Hitting Stats & Trends

Pirates hitters have an OBP of .349 (2,892 PA’s) against RHP this season — best in MLB.

The Pirates are batting .308 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Pirates hitters have an OPS of .781 (2,892 PA’s) against RHP this season — 2nd best in MLB.

Pirates hitters have an OBP of .355 (2,026 PA’s) at home this season — tied for best in MLB.

Cubs Pitching Stats & Trends

Cubs pitchers have picked-off 16 runners from first base this season — most in MLB.

The Cubs pitchers have allowed division opponents to score first in 74% of their games this season — highest in MLB.

Opponents have a groundball batting average of just .219 against Cubs pitchers with runners on base this season — 2nd best in MLB.

In games when their opponents have scored three or more runs in an inning, the Cubs have still managed to win 38% of the time this season — highest in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — tied for 5th highest in MLB.

The Pirates pitchers have allowed their opponents to score first in just 44% of their games at home this season — 3rd lowest in MLB.

The Pirates pitchers have allowed their opponents to score first in just 42% of their games this season — tied for 3rd lowest in MLB.

The Pirates pitchers have allowed their opponents to score first in just 40% of their games on the road this season — 4th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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