Cubs vs White Sox Prediction, Odds & Player Prop Bets Today – MLB, Jul 26

Chicago White Sox's Andrew Benintendi adjusts his helmet while standing on third base during the first inning of a spring training baseball game against the Texas Rangers in Phoenix, Monday, Feb. 26, 2024.
(AP Photo/Ashley Landis)
  • The Cubs are -200 favorites vs the White Sox
  • Cubs vs White Sox Over / Under today: 9.5 Runs
  • Cubs / White Sox TV Channel: MARQ | CHSN

The Chicago Cubs (-200) visit Rate Field to take on the Chicago White Sox (+165) on Saturday, July 26, 2025. First pitch is scheduled for 7:10pm EDT in Chicago, IL.

This season, the Cubs are 60-43 against the spread (ATS), while the White Sox are 60-44 ATS.

Cubs vs White Sox Starting Pitchers Today:

  • Cubs starting pitcher: Cade Horton 3-3, 4.09 ERA
  • White Sox starting pitcher: Aaron Civale 2-6, 4.73 ERA

Cubs vs. White Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cubs-1.5 -125O 9.5 -120-200
White Sox +1.5 +105U 9.5 +100+165

Cubs vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Saturday‘s MLB game with 62.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cubs players for Saturday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

  • Nico Hoerner has hit the Home Runs Over in 2 of his last 10 away games (+16.00 Units / 160% ROI)
  • Pete Crow-Armstrong has hit the Singles Under in 19 of his last 25 away games (+11.25 Units / 33% ROI)
  • Kyle Tucker has hit the Total Bases Under in 13 of his last 15 games (+10.80 Units / 52% ROI)
  • Seiya Suzuki has hit the RBIs Under in 13 of his last 15 away games (+9.35 Units / 34% ROI)
  • Seiya Suzuki has hit the Hits Under in 10 of his last 15 games (+9.15 Units / 45% ROI)

And here are some favorite MLB player prop bets for White Sox players for Saturday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

  • Colson Montgomery has hit the Home Runs Over in 3 of his last 4 games (+25.00 Units / 625% ROI)
  • Mike Tauchman has hit the Hits Over in 13 of his last 15 games (+11.10 Units / 45% ROI)
  • Miguel Vargas has hit the Runs Over in 7 of his last 8 games (+8.90 Units / 111% ROI)
  • Mike Tauchman has hit the Total Bases Over in 12 of his last 15 games (+8.40 Units / 38% ROI)
  • Miguel Vargas has hit the Hits Runs and RBIs Over in 8 of his last 9 games (+7.50 Units / 80% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 52 of their last 101 games (+11.85 Units / 8% ROI)
  • The Chicago Cubs have hit the Moneyline in 58 of their last 97 games (+10.35 Units / 7% ROI)
  • The Chicago Cubs have hit the Team Total Over in 57 of their last 98 games (+8.75 Units / 7% ROI)
  • The Chicago Cubs have hit the Game Total Under in 14 of their last 22 away games (+6.50 Units / 27% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 55 of their last 99 games (+6.45 Units / 5% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 35 of their last 51 games at home (+16.45 Units / 26% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 32 of their last 80 games (+12.35 Units / 15% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in their last 12 games (+12.20 Units / 78% ROI)
  • The Chicago White Sox have covered the Run Line in 49 of their last 80 games (+12.10 Units / 12% ROI)
  • The Chicago White Sox have hit the Team Total Over in 24 of their last 38 games at home (+8.29 Units / 19% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 50-53 against the Run Line (-2.68 Units / -2.17% ROI).

  • 60-43 when betting on the Moneyline for +8.25 Units / 5.49% ROI
  • 52-46 when betting on the total runs Over for +1.95 Units / 1.73% ROI
  • 46-52 when betting on the total runs Under for -11.35 Units / -9.95% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 60-44 against the Run Line (+8.9 Units / 6.95% ROI).

  • 38-66 when betting on the Moneyline for -9.86 Units / -9.44% ROI
  • 46-52 when betting on the total runs Over for -11.7 Units / -10.18% ROI
  • 52-46 when betting on the total runs Under for +1.15 Units / 1.01% ROI

White Sox vs Cubs Home Run Prop Bets Today

Over Under
Michael Busch (CHC) 0.5 +300 0.5 -375
Seiya Suzuki (CHC) 0.5 +310 0.5 -400
Kyle Tucker (CHC) 0.5 +310 0.5 -400
Pete Crow-Armstrong (CHC) 0.5 +350 0.5 -450
Ian Happ (CHC) 0.5 +360 0.5 -500

White Sox vs Cubs Total Hits Prop Bets Today

Over Under
Michael Busch (CHC) 0.5 -275 0.5 +195
Nico Hoerner (CHC) 0.5 -250 0.5 +185
Pete Crow-Armstrong (CHC) 0.5 -250 0.5 +190
Kyle Tucker (CHC) 0.5 -250 0.5 +185
Chase Meidroth (CWS) 0.5 -235 0.5 +175

White Sox vs Cubs RBI Prop Bets Today

Over Under
Pete Crow-Armstrong (CHC) 0.5 +120 0.5 -160
Seiya Suzuki (CHC) 0.5 +125 0.5 -160
Michael Busch (CHC) 0.5 +130 0.5 -175
Kyle Tucker (CHC) 0.5 +145 0.5 -190
Carson Kelly (CHC) 0.5 +150 0.5 -200

White Sox vs Cubs Strikeout Prop Bets Today

Over Under
Aaron Civale (CWS) 3.5 -130 3.5 +100

Cade Horton has a first-pitch strike rate of just 43% (9/21) over the past seven days (1 game) — lowest among NL Starters over the last week; League Avg: 64% — second Percentile.

34% of Cade Horton’s strikeouts are on pitches in the zone this season — 5th lowest in MLB among starting pitchers with at least 40 total IP; League Avg: 50% — third Percentile.

Hitters have chased 56 of Cade Horton’s 133 sliders out of the zone (chase rate of 42%) this season — 4th highest in MLB among starting pitchers with at least 40 total IP; League Avg: 31% — 96th Percentile.

Cade Horton had a first-pitch strike rate of just 43% (9/21) in his last start — lowest in MLB over the last week; League Avg: 64% — first Percentile.

White Sox Starting Pitcher Stats & Trends

Aaron Civale has allowed three-ball counts to 34% of left-handed batters he faced (42/125 PA’s) this season — highest in MLB among starting pitchers with at least 40 total IP; League Avg: 21% — 0 Percentile.

Opponents are hitting just .154 (6-for-39) against Aaron Civale over the last 14 days — 3rd best among AL Starters over the last two weeks; League Avg: .244 — 95th Percentile.

Aaron Civale has thrown elevated pitches 50% of the time (275/547) vs left-handed batters this season — highest in MLB among starting pitchers with at least 40 total IP; League Avg: 31% — 100th Percentile.

Opponents have a miss rate of just 15% (24/158) against Aaron Civale this month (4 games) — 5th lowest among qualified SPs in MLB; League Avg: 24% — fifth Percentile.

Cubs Keys to the Game vs. the White Sox

The Cubs are 30-12 (.714) after a loss this season — best in MLB; League Avg: .493.

The Cubs are 26-6 (.812) when they’ve scored in the first inning this season — best in MLB; League Avg: .633.

The Cubs are 75-45 (.625) after a loss since last season — best in MLB; League Avg: .499.

The Cubs are 60-43 (.583) this season — 4th best in MLB; League Avg: .500.

White Sox Keys to the Game vs. the Cubs

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

The White Sox are just 64-31 (.674) when leading entering the 7th inning since last season — lowest in MLB; League Avg: .865.

The White Sox are just 8-118 (.063) when allowing 5 or more runs since last season — lowest in MLB; League Avg: .198.

The White Sox are just 79-187 (.297) since last season — lowest in MLB; League Avg: .500.

The Cubs are batting just .223 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB; League Avg: .257.

Cubs hitters have an OBP of just .242 (253 PA’s) against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB; League Avg: .319.

Cubs hitters are slugging .445 this season — 2nd best in MLB; League Avg: .401.

The Cubs are batting .377 on the first pitch of at-bats this season — 2nd best in MLB; League Avg: .340.

The White Sox have a winning percentage of just 25% on the road since last season — lowest in MLB; League Avg: 47%.

White Sox hitters have an OPS of just .628 (7,220 PA’s) against RHP since last season — lowest in MLB; League Avg: .717.

The White Sox have a winning percentage of just 30% since last season — lowest in MLB; League Avg: 50%.

The White Sox have a winning percentage of just 34% at home since last season — lowest in MLB; League Avg: 53%.

Cubs pitchers have walked 7% of batters this season — tied for 2nd best in MLB; League Avg: 8%.

Cubs pitchers have a strikeout rate of just 38% with two-strikes this season — tied for 2nd lowest in MLB; League Avg: 42%.

Opponents have a miss rate of just 23% against Cubs pitchers this season — 3rd lowest in MLB; League Avg: 25%.

Opponents have a miss rate of just 24% against Cubs pitchers since last season — 3rd lowest in MLB; League Avg: 25%.

White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.

The White Sox have won just 8% of road games in which their opponents scored first since last season — lowest in MLB; League Avg: 26%.

The White Sox have won just 14% of games in which their opponents scored first since last season — lowest in MLB; League Avg: 32%.

White Sox pitchers have won only 8% of games in which they have allowed their opponent to score in three different innings since last season — lowest in MLB; League Avg: 26%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.