• The Diamondbacks are -135 favorites vs the Giants
• Diamondbacks vs Giants Over / Under today: 7.5 Runs
• Diamondbacks / Giants TV Channel: NSBA | KNTV | DBTV

The Arizona Diamondbacks (-135) visit Oracle Park to take on the San Francisco Giants (+110) on August 28, 2026. First pitch is scheduled for 10:15 pm in San Francisco, CA.

This season, the Diamondbacks are 71-64 against the spread (ATS), while the Giants are 65-67 ATS.

Diamondbacks vs Giants Starting Pitchers Today:

• Diamondbacks starting pitcher: Kohl Drake 0-1, 5.40 ERA
• Giants starting pitcher: Blade Tidwell 0-0, 3.62 ERA

Diamondbacks vs. Giants Odds, Run Line, Over/Under & Moneyline

Diamondbacks vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Friday‘s MLB game with 53.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Diamondbacks players for Friday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Bets Today:

• Gabriel Moreno has hit the Home Runs Over in 3 of his last 5 away games (+23.30 Units / 466% ROI)
• Corbin Carroll has hit the Walks Over in 16 of his last 25 away games (+15.15 Units / 61% ROI)
• Gabriel Moreno has hit the Total Bases Over in 15 of his last 20 games (+14.30 Units / 71% ROI)
• Gabriel Moreno has hit the Hits Over in 19 of his last 25 away games (+13.85 Units / 30% ROI)
• Lars Nootbaar has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+12.30 Units / 38% ROI)

And here are some favorite MLB player prop bets for Giants players for Friday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

• Drew Gilbert has hit the Home Runs Over in 3 of his last 8 games at home (+21.50 Units / 269% ROI)
• Grant McCray has hit the Singles Under in his last 10 games (+10.00 Units / 49% ROI)
• Rafael Devers has hit the Runs Over in 11 of his last 15 games (+9.60 Units / 62% ROI)
• Rafael Devers has hit the Total Bases Over in his last 7 games at home (+8.45 Units / 112% ROI)
• Rafael Devers has hit the Hits Runs and RBIs Over in his last 7 games at home (+7.30 Units / 87% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 32 of their last 50 away games (+13.25 Units / 23% ROI)
• The Arizona Diamondbacks have hit the Game Total Under in 26 of their last 40 away games (+10.80 Units / 25% ROI)
• The Arizona Diamondbacks have hit the Moneyline in 13 of their last 21 away games (+10.20 Units / 47% ROI)
• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 9 of their last 21 away games (+2.70 Units / 12% ROI)
• The Arizona Diamondbacks have covered the Run Line in 5 of their last 8 games (+2.45 Units / 24% ROI)

Giants Best Bets Today:

• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 16 of their last 19 games at home (+12.90 Units / 57% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 15 of their last 23 games at home (+12.85 Units / 44% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 10 of their last 12 games (+8.60 Units / 63% ROI)
• The San Francisco Giants have hit the Game Total Under in 21 of their last 35 games at home (+6.70 Units / 17% ROI)
• The San Francisco Giants have covered the Run Line in 14 of their last 23 games at home (+5.25 Units / 18% ROI)

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 72-59 against the Run Line (+2 Units / 1.1% ROI).

• 71-64 when betting on the Moneyline for +7.9 Units / 4.99% ROI
• 58-71 when betting on the total runs Over for -20.1 Units / -13.49% ROI
• 71-58 when betting on the total runs Under for +7.65 Units / 5.17% ROI

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 65-67 against the Run Line (-17.85 Units / -9.71% ROI).

• 55-79 when betting on the Moneyline for -20.95 Units / -14.09% ROI
• 60-62 when betting on the total runs Over for -8.2 Units / -5.55% ROI
• 62-60 when betting on the total runs Under for -3.8 Units / -2.58% ROI

Giants vs Diamondbacks Home Run Prop Bets Today

Giants vs Diamondbacks Total Hits Prop Bets Today

Giants vs Diamondbacks Strikeout Prop Bets Today

Diamondbacks Keys to the Game vs. the Giants

The Diamondbacks are 10-47 (.175) when trailing entering the 7th inning this season — tied for 4th best in MLB.

The Diamondbacks are 61-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB.

The Diamondbacks are 9-120 (.070) when trailing entering the 9th inning since the 2025 season — 2nd best in MLB.

The Diamondbacks were just 67-7 (.905) when leading entering the 9th inning in the 2025 season — 2nd lowest in MLB; League Avg: .956.

Giants Keys to the Game vs. the Diamondbacks

The Giants are just 1-58 (.017) when trailing entering the 7th inning this season — lowest in MLB.

The Giants are just 1-61 (.016) when trailing entering the 8th inning this season — lowest in MLB.

The Giants are just 50-9 (.847) when leading entering the 9th inning this season — 2nd lowest in MLB.

The Giants are just 2-64 (.030) when trailing entering the 9th inning this season — 3rd lowest in MLB.

Diamondbacks Hitting Stats & Trends

The Diamondbacks are batting .279 against LHP this season — best in MLB.

Diamondbacks hitters are slugging .450 against LHP this season — best in MLB.

Diamondbacks hitters have struck out in just 18% of their PA’s against LHP this season — best in MLB.

The Diamondbacks are batting .294 in lefty-lefty matchups this season — best in MLB.

Giants Hitting Stats & Trends

The Giants are batting .255 with two outs this season — 2nd best in MLB.

The Giants are just 1-58 (.017) when trailing entering the 7th inning this season — lowest in MLB.

Giants hitters have an OBP of just .291 (1,440 PA’s) against LHP this season — lowest in MLB.

29% of Giants hitters strikeouts have come on 95+ MPH fastballs this season — highest in MLB.

Diamondbacks Pitching Stats & Trends

Diamondbacks pitchers have a strikeout rate of just 38% with two-strikes this season — 3rd lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 17% with runners in scoring position this season — 2nd lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 17% in the first 5 innings this season — 2nd lowest in MLB.

Diamondbacks pitchers have walked 8% of batters this season — 4th best in MLB.

Giants Pitching Stats & Trends

Opponents have a groundball rate of 46% against Giants pitchers this season — highest in MLB.

The Giants have won just 6% of road games in which their opponents scored first this season — lowest in MLB.

The Giants have won just 23% of games in which their opponents scored first this season — 2nd lowest in MLB.

Giants pitchers have a strikeout rate of just 20% this season — 4th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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