- The Diamondbacks are -102 favorites vs the Padres
- Diamondbacks vs Padres Over / Under today: 7.5 Runs
- Diamondbacks / Padres TV Channel: DBTV | PDTV
The Arizona Diamondbacks (-102) visit Petco Park to take on the San Diego Padres (-118) on September 26, 2026. First pitch is scheduled for 8:40 pm in San Diego, CA.
This season, the Diamondbacks are 86-74 against the spread (ATS), while the Padres are 87-70 ATS.
Diamondbacks vs Padres Starting Pitchers Today:
- Diamondbacks starting pitcher: Undecided 0-0, 0.00 ERA
- Padres starting pitcher: Walker Buehler 9-6, 4.59 ERA
Diamondbacks vs. Padres Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Diamondbacks | -1.5 +165 | O 7.5 -110 | -102 |
| Padres | +1.5 -200 | U 7.5 -110 | -118 |
Diamondbacks vs Padres Prediction for Today’s Game
Based on recent trends the model predicts the Padres will win Saturday‘s MLB game with 57.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Diamondbacks players for Saturday‘s game, looking at profitable historical betting trends:
Best Diamondbacks Player Prop Bets Today:
- Nolan Arenado has hit the Home Runs Over in 5 of his last 8 games (+24.90 Units / 311% ROI)
- Gabriel Moreno has hit the Total Bases Over in 18 of his last 25 games (+14.95 Units / 57% ROI)
- Ketel Marte has hit the Hits Under in 16 of his last 25 away games (+12.70 Units / 38% ROI)
- Gabriel Moreno has hit the Hits Runs and RBIs Over in 19 of his last 25 away games (+11.65 Units / 38% ROI)
- Lars Nootbaar has hit the Runs Under in 19 of his last 25 games (+11.45 Units / 34% ROI)
And here are some favorite MLB player prop bets for Padres players for Saturday‘s game, looking at profitable historical betting trends:
Best Padres Player Prop Best Bets Today:
- Manny Machado has hit the Hits Under in 12 of his last 15 games (+13.90 Units / 76% ROI)
- Jake Cronenworth has hit the Home Runs Over in 2 of his last 7 games at home (+13.00 Units / 186% ROI)
- Fernando Tatis Jr. has hit the Runs Over in 18 of his last 25 games (+10.75 Units / 33% ROI)
- Manny Machado has hit the Singles Under in 12 of his last 15 games (+8.90 Units / 49% ROI)
- Dustin Harris has hit the Hits Runs and RBIs Over in 14 of his last 20 games (+8.85 Units / 40% ROI)
Diamondbacks Best Bets Today:
- The Arizona Diamondbacks have hit the Moneyline in 23 of their last 35 away games (+15.70 Units / 40% ROI)
- The Arizona Diamondbacks have hit the Game Total Under in 33 of their last 50 away games (+14.55 Units / 27% ROI)
- The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 30 of their last 50 away games (+7.80 Units / 13% ROI)
- The Arizona Diamondbacks have covered the Run Line in their last 6 games (+6.85 Units / 101% ROI)
- The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in their last 6 games (+6.35 Units / 77% ROI)
Padres Best Bets Today:
- The San Diego Padres have hit the Moneyline in 32 of their last 45 games at home (+16.90 Units / 28% ROI)
- The San Diego Padres have hit the Team Total Over in 27 of their last 40 games (+12.15 Units / 26% ROI)
- The San Diego Padres have covered the Run Line in 27 of their last 45 games (+10.60 Units / 18% ROI)
- The San Diego Padres have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 18 games (+10.15 Units / 49% ROI)
- The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 13 of their last 18 games (+9.90 Units / 38% ROI)
Diamondbacks Against the Spread (ATS) Record
Against the spread this season, the Diamondbacks are 84-71 against the Run Line (+2.1 Units / 1% ROI).
- 86-74 when betting on the Moneyline for +11.05 Units / 5.83% ROI
- 69-85 when betting on the total runs Over for -24.6 Units / -13.93% ROI
- 85-69 when betting on the total runs Under for +9.55 Units / 5.44% ROI
Padres Against the Spread (ATS) Record
Against the spread this season, the Padres are 87-70 against the Run Line (+11.7 Units / 5.58% ROI).
- 89-71 when betting on the Moneyline for +12.55 Units / 6.35% ROI
- 75-80 when betting on the total runs Over for -13.1 Units / -7.41% ROI
- 80-75 when betting on the total runs Under for -1.9 Units / -1.08% ROI
Diamondbacks Keys to the Game vs. the Padres
The Diamondbacks are 72-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB.
The Diamondbacks were just 67-7 (.905) when leading entering the 9th inning in the 2025 season — 2nd lowest in MLB; League Avg: .956.
The Diamondbacks are 10-129 (.072) when trailing entering the 9th inning since the 2025 season — 2nd best in MLB.
The Diamondbacks were 67-15 (.807) when they allowed 4 or fewer runs in the 2024 season — 3rd best in MLB; League Avg: .723.
Padres Keys to the Game vs. the Diamondbacks
The Padres are 63-8 (.887) when scoring 5 or more runs this season — 2nd best in MLB.
The Padres are 64-5 (.928) when leading entering the 7th inning this season — 2nd best in MLB.
The Padres are 71-2 (.973) when leading entering the 8th inning this season — tied for 2nd best in MLB.
The Padres are 13-8 (.619) when tied entering the 7th inning this season — tied for 4th best in MLB.
Diamondbacks Hitting Stats & Trends
The Diamondbacks are batting .276 against LHP this season — best in MLB.
Diamondbacks hitters have struck out in just 18% of their PA’s against LHP this season — best in MLB.
Diamondbacks hitters are slugging .443 against LHP this season — 2nd best in MLB.
Diamondbacks hitters have an OPS of .785 (1,669 PA’s) against LHP this season — 2nd best in MLB.
Padres Hitting Stats & Trends
The Padres have won 94% of home games in which they have scored three or more runs in an inning this season — 2nd highest in MLB.
Padres hitters have an OBP of just .305 (749 PA’s) when facing the starting pitcher for the 3rd time in a game this season — 5th lowest in MLB.
The Padres are batting .366 on the first pitch of at-bats this season — 2nd best in MLB.
The Padres are batting .248 on the road this season — tied for 4th best in MLB.
Diamondbacks Pitching Stats & Trends
Opponents have a miss rate of just 23% against Diamondbacks pitchers this season — 2nd lowest in MLB.
Diamondbacks pitchers have walked 7% of batters when facing the leadoff batter in the inning this season — tied for 2nd best in MLB.
Diamondbacks pitchers have a strikeout rate of just 17% when facing the leadoff batter in the inning this season — lowest in MLB.
The Diamondbacks have won 44% of games in which their opponents scored first this season — 2nd highest in MLB.
Padres Pitching Stats & Trends
The Padres have won 46% of home games in which their opponents scored first this season — 2nd highest in MLB.
The Padres have won 41% of games in which their opponents scored first this season — 5th highest in MLB.
Padres pitchers have a strikeout rate of 29% in close and late situations this season — 2nd best in MLB.
The Padres have allowed 1.08 runs per game (173/160) in late innings this season — 2nd best in MLB.
More MLB Reading:
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