• The Dodgers are -375 favorites vs the Giants
• Dodgers vs Giants Over / Under today: 7.5 Runs
• Dodgers / Giants TV Channel: NSBA | SNLA

The Los Angeles Dodgers (-375) visit Oracle Park to take on the San Francisco Giants (+290) on September 25, 2026. First pitch is scheduled for 10:15 pm in San Francisco, CA.

This season, the Dodgers are 97-62 against the spread (ATS), while the Giants are 78-79 ATS.

Dodgers vs Giants Starting Pitchers Today:

• Dodgers starting pitcher: Tarik Skubal 11-7, 2.84 ERA
• Giants starting pitcher: Yunior Marte 0-0, 108.11 ERA

Dodgers vs. Giants Odds, Run Line, Over/Under & Moneyline

Dodgers vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Dodgers will win Friday‘s MLB game with 63.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Dodgers players for Friday‘s game, looking at profitable historical betting trends:

Best Dodgers Player Prop Bets Today:

• Shohei Ohtani has hit the Runs Under in 19 of his last 25 away games (+14.65 Units / 52% ROI)
• Tommy Edman has hit the Home Runs Over in 2 of his last 4 games (+11.80 Units / 295% ROI)
• Teoscar Hernández has hit the Hits Runs and RBIs Over in 16 of his last 20 games (+11.55 Units / 48% ROI)
• Shohei Ohtani has hit the Walks Under in 20 of his last 25 away games (+11.55 Units / 29% ROI)
• Shohei Ohtani has hit the Hits Under in 11 of his last 15 games (+9.80 Units / 43% ROI)

And here are some favorite MLB player prop bets for Giants players for Friday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

• Jonah Cox has hit the Runs Over in 14 of his last 25 games (+10.80 Units / 43% ROI)
• Turner Hill has hit the Hits Under in 8 of his last 9 games at home (+10.25 Units / 114% ROI)
• Turner Hill has hit the Singles Under in his last 9 games at home (+9.10 Units / 83% ROI)
• Drew Cavanaugh has hit the Home Runs Over in 1 of his last 4 games at home (+9.00 Units / 225% ROI)
• Turner Hill has hit the Total Bases Under in 8 of his last 9 games at home (+8.75 Units / 81% ROI)

Dodgers Best Bets Today:

• The Los Angeles Dodgers have hit the Team Total Under in 25 of their last 40 away games (+8.05 Units / 17% ROI)
• The Los Angeles Dodgers have hit the Game Total Under in 12 of their last 19 away games (+6.55 Units / 31% ROI)
• The Los Angeles Dodgers have hit the Moneyline in 15 of their last 20 games (+5.85 Units / 13% ROI)
• The Los Angeles Dodgers have hit the 1st Five Innings (F5) Team Total Over in 21 of their last 35 games (+5.10 Units / 12% ROI)
• The Los Angeles Dodgers have covered the Run Line in 11 of their last 17 games (+5.00 Units / 24% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 29 of their last 40 games (+16.45 Units / 33% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 20 of their last 35 games at home (+12.80 Units / 30% ROI)
• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 22 of their last 30 games at home (+12.40 Units / 33% ROI)
• The San Francisco Giants have hit the Team Total Over in 20 of their last 30 games (+8.75 Units / 25% ROI)
• The San Francisco Giants have hit the Game Total Over in 14 of their last 23 games (+5.10 Units / 20% ROI)

Dodgers Against the Spread (ATS) Record

Against the spread this season, the Dodgers are 69-89 against the Run Line (-26.05 Units / -13.87% ROI).

• 97-62 when betting on the Moneyline for -17.8 Units / -5.69% ROI
• 72-83 when betting on the total runs Over for -19.6 Units / -11.17% ROI
• 83-72 when betting on the total runs Under for +3.9 Units / 2.24% ROI

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 78-79 against the Run Line (-20.45 Units / -9.34% ROI).

• 65-94 when betting on the Moneyline for -23.3 Units / -13.38% ROI
• 75-71 when betting on the total runs Over for -3.2 Units / -1.82% ROI
• 71-75 when betting on the total runs Under for -11.25 Units / -6.45% ROI

Dodgers Keys to the Game vs. the Giants

The Dodgers are 49-14 (.778) vs the bottom 10 runs allowed teams this season Today, they face the Giants (23rd fewest runs allowed).

The Dodgers are 26-19 (.578) when their opponents score in the first inning this season — best in MLB.

The Dodgers are 41-16 (.719) vs bottom 10 scoring offenses this season Today, they face the Giants (24th in runs scored).

The Dodgers are 37-52 (.416) when scoring 4 or fewer runs this season — 2nd best in MLB.

Giants Keys to the Game vs. the Dodgers

The Giants are just 2-69 (.028) when trailing entering the 7th inning this season — tied for lowest in MLB.

The Giants are just 19-31 (.380) vs bottom 10 scoring offenses this season Today, they face the Dodgers (fourth in runs scored).

The Giants are just 18-80 (.184) when scoring 4 or fewer runs this season — tied for lowest in MLB.

The Giants are just 59-9 (.868) when leading entering the 9th inning this season — 2nd lowest in MLB.

Dodgers Hitting Stats & Trends

Dodgers hitters have an OPS of .779 (3,126 PA’s) on the road this season — best in MLB.

Dodgers hitters have an OBP of .349 (3,126 PA’s) on the road this season — best in MLB.

The Dodgers are batting .265 on the road this season — best in MLB.

Dodgers hitters have an OBP of .339 (6,100 PA’s) this season — tied for 2nd best in MLB.

Giants Hitting Stats & Trends

Giants hitters have an OBP of just .308 (5,962 PA’s) this season — 2nd lowest in MLB.

30% of Giants hitters strikeouts have come on 95+ MPH fastballs this season — highest in MLB.

Giants hitters have drawn walks in 8% of their PA’s against RHP this season — 2nd lowest in MLB.

Giants hitters have an OBP of just .235 (3,164 PA’s) with two-strikes this season — 3rd lowest in MLB.

Dodgers Pitching Stats & Trends

Dodgers pitchers have a strikeout rate of 25% this season — 3rd best in MLB.

Dodgers pitchers have a strikeout rate of 46% with two-strikes this season — 2nd best in MLB.

The Dodgers have allowed 3.55 runs per game (277/78) on the road this season — 2nd best in MLB.

Opponents have a miss rate of 28% against Dodgers pitchers this season — 2nd best in MLB.

Giants Pitching Stats & Trends

Opponents have a groundball rate of 46% against Giants pitchers this season — highest in MLB.

Opponents have a miss rate of just 23% against Giants pitchers this season — tied for 3rd lowest in MLB.

The Giants have won just 5% of road games in which their opponents scored first this season — lowest in MLB.

Giants pitchers have thrown at least two strikes in their first three pitches to 59% of opposing batters this season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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