• The Giants are +105 favorites vs the Diamondbacks
• Giants vs Diamondbacks Over / Under today: 8.5 Runs
• Giants / Diamondbacks TV Channel: NSBA | DBTV

The San Francisco Giants (+105) visit Chase Field to take on the Arizona Diamondbacks (-125) on May 19, 2026. First pitch is scheduled for 9:40 pm in Phoenix, AZ.

This season, the Giants are 20-28 against the spread (ATS), while the Diamondbacks are 28-17 ATS.

Giants vs Diamondbacks Starting Pitchers Today:

• Giants starting pitcher: Landen Roupp 5-4, 3.49 ERA
• Diamondbacks starting pitcher: Ryne Nelson 1-3, 5.37 ERA

Giants vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

Giants vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Tuesday‘s MLB game with 53.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Giants vs Diamondbacks and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Giants players for Tuesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

• Luis Arraez has hit the Home Runs Over in 2 of his last 4 games (+21.00 Units / 525% ROI)
• Harrison Bader has hit the Total Bases Over in 19 of his last 25 away games (+14.05 Units / 42% ROI)
• Matt Chapman has hit the Runs Under in 14 of his last 15 games (+12.30 Units / 44% ROI)
• Matt Chapman has hit the Singles Under in 17 of his last 20 games (+12.00 Units / 39% ROI)
• Matt Chapman has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+11.45 Units / 34% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Tuesday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

• Nolan Arenado has hit the Home Runs Over in 3 of his last 10 games at home (+11.60 Units / 116% ROI)
• Jose Fernandez has hit the Singles Over in 18 of his last 25 games (+11.20 Units / 41% ROI)
• Ketel Marte has hit the RBIs Under in 20 of his last 25 games (+10.75 Units / 22% ROI)
• Jose Fernandez has hit the Hits Over in 19 of his last 25 games (+10.30 Units / 23% ROI)
• Lourdes Gurriel Jr. has hit the Total Bases Under in 18 of his last 25 games at home (+9.10 Units / 25% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the Team Total Under in 23 of their last 35 away games (+9.30 Units / 23% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 29 of their last 50 games (+4.65 Units / 8% ROI)
• The San Francisco Giants have hit the Game Total Under in 19 of their last 35 away games (+4.60 Units / 12% ROI)
• The San Francisco Giants have hit the Moneyline in 5 of their last 9 games (+3.65 Units / 39% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 3 of their last 7 games (+1.50 Units / 21% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 26 of their last 35 games at home (+15.50 Units / 36% ROI)
• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 27 of their last 50 games at home (+11.25 Units / 17% ROI)
• The Arizona Diamondbacks have hit the Moneyline in 28 of their last 45 games at home (+9.40 Units / 17% ROI)
• The Arizona Diamondbacks have covered the Run Line in 22 of their last 35 games at home (+8.30 Units / 18% ROI)
• The Arizona Diamondbacks have hit the Team Total Over in 22 of their last 35 games (+7.55 Units / 18% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 20-27 against the Run Line (-17.15 Units / -24.82% ROI).

• 20-28 when betting on the Moneyline for -5.45 Units / -10.54% ROI
• 21-24 when betting on the total runs Over for -5.35 Units / -10.1% ROI
• 24-21 when betting on the total runs Under for +1 Units / 1.9% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 28-17 against the Run Line (+5.9 Units / 9.06% ROI).

• 23-23 when betting on the Moneyline for +0.65 Units / 1.26% ROI
• 24-20 when betting on the total runs Over for +2.1 Units / 4.13% ROI
• 20-24 when betting on the total runs Under for -6.2 Units / -12.28% ROI

Diamondbacks vs Giants Home Run Prop Bets Today

Diamondbacks vs Giants Total Hits Prop Bets Today

Diamondbacks vs Giants Strikeout Prop Bets Today

Giants Keys to the Game vs. the Diamondbacks

The Giants are just 5-26 (.161) when scoring 4 or fewer runs this season — lowest in MLB; League Avg: .277.

The Giants are just 0-24 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .103.

The Giants are just 0-25 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .050.

The Giants are just 0-22 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .133.

Diamondbacks Keys to the Game vs. the Giants

The Diamondbacks are just 0-19 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .050.

The Diamondbacks are just 2-11 (.154) when allowing 2 or more home runs this season — 3rd lowest in MLB; League Avg: .292.

The Diamondbacks are just 78-21 (.788) when leading entering the 7th inning since the 2025 season — 2nd lowest in MLB; League Avg: .873.

The Diamondbacks are just 86-15 (.851) when leading entering the 8th inning since the 2025 season — 2nd lowest in MLB; League Avg: .907.

Giants Hitting Stats & Trends

Giants hitters have drawn walks in 6% of their PA’s against RHP this season — lowest in MLB.

Giants hitters have an OBP of just .292 (1,770 PA’s) this season — lowest in MLB.

Giants hitters have drawn walks in 6% of their PA’s this season — lowest in MLB.

The Giants have an average HR distance of 375.8 feet this season — lowest in MLB.

Diamondbacks Hitting Stats & Trends

Diamondbacks hitters have a swing rate of just 24% on the first pitch of at-bats this season — lowest in MLB.

9% of Diamondbacks’ hitters plate appearances have lasted only one pitch (149/1,707 PA’s) this season — 2nd lowest in MLB.

Diamondbacks hitters have put 41% of their swings in play against LHP this season — highest in MLB.

The Diamondbacks are batting .277 against LHP this season — best in MLB.

Giants Pitching Stats & Trends

Giants pitchers have thrown at least two strikes in their first three pitches to 55% of opposing batters this season — lowest in MLB.

Giants pitchers have induced opposing hitters to ground into 45 double plays in 346 opportunities (13%) this season — best in MLB.

Opponents have a groundball rate of 47% against Giants pitchers this season — 3rd highest in MLB.

Giants pitchers have a strikeout rate of just 19% in late innings this season — 2nd lowest in MLB.

Diamondbacks Pitching Stats & Trends

Opponents have a miss rate of just 23% against Diamondbacks pitchers this season — 5th lowest in MLB.

Diamondbacks pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — tied for 2nd best in MLB.

Diamondbacks pitchers have walked 8% of batters this season — tied for 4th best in MLB.

Diamondbacks pitchers have allowed an average Exit Velocity of 89.8 MPH (1,154 batted balls) this season — 5th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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