• The Guardians are -220 favorites vs the Giants
• Giants vs Guardians Over / Under today: 7.5 Runs
• Giants / Guardians TV Channel: GDTV | NSBA

The San Francisco Giants (+180) visit Progressive Field to take on the Cleveland Guardians (-220) on August 19, 2026. First pitch is scheduled for 6:40 pm in Cleveland, OH.

This season, the Giants are 51-74 against the spread (ATS), while the Guardians are 59-66 ATS.

Giants vs Guardians Starting Pitchers Today:

• Giants starting pitcher: Matthew Wilkinson 0-0, 0.00 ERA
• Guardians starting pitcher: Parker Messick 9-7, 2.61 ERA

Giants vs. Guardians Odds, Run Line, Over/Under & Moneyline

Giants vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Wednesday‘s MLB game with 60.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

• Osleivis Basabe has hit the Home Runs Over in 3 of his last 6 away games (+26.00 Units / 433% ROI)
• Christian Koss has hit the Hits Over in his last 8 games (+8.00 Units / 70% ROI)
• Christian Koss has hit the Total Bases Over in his last 8 games (+8.00 Units / 70% ROI)
• Bryce Eldridge has hit the Walks Under in his last 8 away games (+8.00 Units / 58% ROI)
• Christian Koss has hit the Hits Runs and RBIs Under in 11 of his last 15 away games (+7.50 Units / 39% ROI)

And here are some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

• Patrick Bailey has hit the Home Runs Over in 3 of his last 9 games at home (+18.00 Units / 200% ROI)
• Steven Kwan has hit the Hits Over in 21 of his last 25 games at home (+13.65 Units / 27% ROI)
• Steven Kwan has hit the Singles Over in 20 of his last 25 games at home (+13.60 Units / 42% ROI)
• Brayan Rocchio has hit the Hits Runs and RBIs Under in 17 of his last 20 games (+13.10 Units / 46% ROI)
• Nate Lowe has hit the Total Bases Over in 16 of his last 20 games (+13.05 Units / 46% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the Team Total Under in 30 of their last 50 games (+7.25 Units / 12% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 20 of their last 40 games (+7.20 Units / 15% ROI)
• The San Francisco Giants have hit the Game Total Over in 21 of their last 40 away games (+6.70 Units / 15% ROI)
• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 8 of their last 10 games (+6.00 Units / 49% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 7 of their last 11 away games (+3.25 Units / 27% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 7 of their last 8 games at home (+5.60 Units / 55% ROI)
• The Cleveland Guardians have hit the Team Total Over in 10 of their last 14 games at home (+5.40 Units / 34% ROI)
• The Cleveland Guardians have hit the Game Total Over in 26 of their last 45 games at home (+5.10 Units / 10% ROI)
• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 6 of their last 11 games at home (+0.80 Units / 6% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 59-64 against the Run Line (-20.15 Units / -11.69% ROI).

• 51-74 when betting on the Moneyline for -21.25 Units / -15.24% ROI
• 57-57 when betting on the total runs Over for -5.85 Units / -4.24% ROI
• 57-57 when betting on the total runs Under for -5.5 Units / -4.02% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 59-66 against the Run Line (-11.7 Units / -7.19% ROI).

• 61-65 when betting on the Moneyline for -9.6 Units / -6.33% ROI
• 61-65 when betting on the total runs Over for -10 Units / -7.26% ROI
• 65-61 when betting on the total runs Under for -2.8 Units / -2% ROI

Guardians vs Giants Home Run Prop Bets Today

Guardians vs Giants Total Hits Prop Bets Today

Guardians vs Giants Strikeout Prop Bets Today

Giants Keys to the Game vs. the Guardians

The Giants are just 3-7 (.300) when allowing 5 or more extra base hits this season — lowest in MLB.

The Giants are just 3-7 (.300) this season — 2nd lowest in MLB.

The Giants are just 3-7 (.300) when allowing 5 or more extra base hits since the 2025 season — lowest in MLB.

The Giants are just 3-7 (.300) since the 2025 season — 2nd lowest in MLB.

Guardians Keys to the Game vs. the Giants

The Guardians are just 3-8 (.273) this season — lowest in MLB.

The Guardians are just 0-7 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB.

The Guardians are just 3-6 (.333) when allowing 5 or more extra base hits this season — 2nd lowest in MLB.

The Guardians are just 3-8 (.273) since the 2025 season — lowest in MLB.

Giants Hitting Stats & Trends

The Giants are batting .255 with two outs this season — 2nd best in MLB.

Giants hitters have struck out in just 20% of their PA’s against RHP this season — 4th best in MLB.

The Giants have a winning percentage of just 35% on the road this season — 3rd lowest in MLB.

Giants hitters have an OBP of just .308 (2,252 PA’s) at home this season — 4th lowest in MLB.

Guardians Hitting Stats & Trends

The Guardians are hitting just .175 against pitchers who have thrown at least 80 pitches in the game this season — lowest in MLB.

The Guardians are batting just .220 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

Guardians hitters have an OPS of just .541 (323 PA’s) against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB.

The Guardians are batting just .218 on the road this season — lowest in MLB.

Giants Pitching Stats & Trends

Opponents have a groundball rate of 46% against Giants pitchers this season — highest in MLB.

Giants pitchers have thrown at least two strikes in their first three pitches to 59% of opposing batters this season — lowest in MLB.

Giants pitchers have a strikeout rate of just 19% in late innings this season — tied for lowest in MLB.

Giants pitchers have won only 16% of games in which they have allowed their opponent to score in three different innings this season — 2nd lowest in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 25% with runners in scoring position this season — 2nd best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 3rd best in MLB.

Opponents have a miss rate of 27% against Guardians pitchers this season — 4th best in MLB.

Guardians pitchers have a strikeout rate of 27% in late innings this season — best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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