• The Guardians are -210 favorites vs the Giants
• Giants vs Guardians Over / Under today: 7 Runs
• Giants / Guardians TV Channel: GDTV | NSBA

The San Francisco Giants (+170) visit Progressive Field to take on the Cleveland Guardians (-210) on August 20, 2026. First pitch is scheduled for 1:10 pm in Cleveland, OH.

This season, the Giants are 52-74 against the spread (ATS), while the Guardians are 59-67 ATS.

Giants vs Guardians Starting Pitchers Today:

• Giants starting pitcher: Landen Roupp 7-12, 4.34 ERA
• Guardians starting pitcher: Gavin Williams 11-7, 3.75 ERA

Giants vs. Guardians Odds, Run Line, Over/Under & Moneyline

Giants vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Thursday‘s MLB game with 60.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Giants players for Thursday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

• Drew Gilbert has hit the Home Runs Over in 2 of his last 6 games (+14.00 Units / 233% ROI)
• Landen Roupp has hit the Walks Allowed Over in 7 of his last 8 games (+6.85 Units / 73% ROI)
• Buddy Kennedy has hit the Singles Under in 8 of his last 9 away games (+6.20 Units / 35% ROI)
• Buddy Kennedy has hit the Hits Runs and RBIs Under in 7 of his last 9 away games (+5.45 Units / 60% ROI)
• Buddy Kennedy has hit the Hits Under in 7 of his last 9 away games (+5.20 Units / 50% ROI)

And here are some favorite MLB player prop bets for Guardians players for Thursday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

• Patrick Bailey has hit the Home Runs Over in 3 of his last 9 games at home (+18.00 Units / 200% ROI)
• Chase DeLauter has hit the Walks Under in 20 of his last 25 games at home (+10.20 Units / 20% ROI)
• Chase DeLauter has hit the Hits Over in 20 of his last 25 games at home (+9.65 Units / 17% ROI)
• Patrick Bailey has hit the Singles Under in 16 of his last 20 games (+9.10 Units / 27% ROI)
• Jo Adell has hit the Runs Under in 15 of his last 20 games at home (+7.30 Units / 20% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 20 of their last 40 games (+8.10 Units / 17% ROI)
• The San Francisco Giants have hit the Team Total Under in 30 of their last 50 games (+7.25 Units / 12% ROI)
• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 9 of their last 11 games (+7.20 Units / 54% ROI)
• The San Francisco Giants have hit the Game Total Over in 20 of their last 40 away games (+4.70 Units / 11% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 12 away games (+4.25 Units / 31% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 29 of their last 50 games (+6.55 Units / 11% ROI)
• The Cleveland Guardians have hit the Team Total Over in 10 of their last 15 games at home (+4.40 Units / 26% ROI)
• The Cleveland Guardians have hit the Game Total Over in 9 of their last 14 games (+3.60 Units / 24% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 60-64 against the Run Line (-19.15 Units / -11.04% ROI).

• 52-74 when betting on the Moneyline for -19.3 Units / -13.75% ROI
• 57-58 when betting on the total runs Over for -6.85 Units / -4.93% ROI
• 58-57 when betting on the total runs Under for -4.5 Units / -3.26% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 59-67 against the Run Line (-12.8 Units / -7.82% ROI).

• 61-66 when betting on the Moneyline for -11.85 Units / -7.69% ROI
• 61-66 when betting on the total runs Over for -11 Units / -7.93% ROI
• 66-61 when betting on the total runs Under for -1.8 Units / -1.28% ROI

Guardians vs Giants Home Run Prop Bets Today

Guardians vs Giants Total Hits Prop Bets Today

Guardians vs Giants Strikeout Prop Bets Today

Giants Keys to the Game vs. the Guardians

The Giants are just 3-7 (.300) this season — 2nd lowest in MLB.

The Giants are just 3-7 (.300) when allowing 5 or more extra base hits this season — lowest in MLB.

The Giants are just 3-7 (.300) since the 2025 season — 2nd lowest in MLB.

The Giants are just 3-7 (.300) when allowing 5 or more extra base hits since the 2025 season — lowest in MLB.

Guardians Keys to the Game vs. the Giants

The Guardians are just 3-6 (.333) when allowing 5 or more extra base hits this season — 2nd lowest in MLB.

The Guardians are just 3-8 (.273) this season — lowest in MLB.

The Guardians are just 0-7 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB.

The Guardians are just 3-8 (.273) since the 2025 season — lowest in MLB.

Giants Hitting Stats & Trends

Giants hitters have an OBP of just .293 (1,333 PA’s) against LHP this season — 2nd lowest in MLB.

Giants hitters have an OPS of just .348 (192 PA’s) with two-strikes this season — 2nd lowest in MLB.

The Giants are batting .255 with two outs this season — 2nd best in MLB.

Giants hitters have an OPS of just .663 (1,333 PA’s) against LHP this season — 3rd lowest in MLB.

Guardians Hitting Stats & Trends

The Guardians are batting just .218 on the road this season — lowest in MLB.

The Guardians are batting just .219 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

Guardians hitters are slugging just .283 against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB.

Guardians hitters are slugging just .360 on the road this season — 2nd lowest in MLB.

Giants Pitching Stats & Trends

Opponents have a groundball rate of 46% against Giants pitchers this season — highest in MLB.

Giants pitchers have thrown at least two strikes in their first three pitches to 59% of opposing batters this season — lowest in MLB.

Giants pitchers have walked 10% of batters this season — 5th highest in MLB.

Giants pitchers have a strikeout rate of just 18% this season — 4th lowest in MLB.

Guardians Pitching Stats & Trends

Opponents have a miss rate of 28% against Guardians pitchers this season — 4th best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 5th best in MLB.

Guardians pitchers have a strikeout rate of 29% in close and late situations this season — best in MLB.

Guardians pitchers have a strikeout rate of 27% in late innings this season — best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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