• The Orioles are -125 favorites vs the Giants
• Giants vs Orioles Over / Under today: 8.5 Runs
• Giants / Orioles TV Channel: ATV

The San Francisco Giants (+105) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-125) on April 10, 2026. First pitch is scheduled for 7:15 pm in Baltimore, MD.

This season, the Giants are 5-8 against the spread (ATS), while the Orioles are 4-8 ATS.

Giants vs Orioles Starting Pitchers Today:

• Giants starting pitcher: Landen Roupp 1-1, 4.22 ERA
• Orioles starting pitcher: Shane Baz 0-0, 3.49 ERA

Giants vs. Orioles Odds, Run Line, Over/Under & Moneyline

Giants vs Orioles Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Friday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Giants vs Orioles and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Giants players for Friday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

• Rafael Devers has hit the Walks Over in 16 of his last 25 away games (+11.30 Units / 44% ROI)
• Luis Arraez has hit the Singles Over in 20 of his last 25 games (+10.50 Units / 23% ROI)
• Jung Hoo Lee has hit the Hits Under in 10 of his last 15 games (+10.30 Units / 62% ROI)
• Harrison Bader has hit the Home Runs Over in 2 of his last 6 away games (+9.40 Units / 157% ROI)
• Harrison Bader has hit the Total Bases Under in 14 of his last 20 games (+9.25 Units / 40% ROI)

And here are some favorite MLB player prop bets for Orioles players for Friday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Best Bets Today:

• Pete Alonso has hit the Hits Over in 21 of his last 25 games at home (+14.25 Units / 27% ROI)
• Gunnar Henderson has hit the Home Runs Over in 4 of his last 9 games (+13.20 Units / 147% ROI)
• Pete Alonso has hit the Singles Over in 16 of his last 25 games at home (+9.20 Units / 37% ROI)
• Pete Alonso has hit the Total Bases Over in 16 of his last 25 games at home (+9.10 Units / 35% ROI)
• Shane Baz has hit the Walks Allowed Over in 18 of his last 25 games (+8.40 Units / 22% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 26 of their last 40 away games (+10.40 Units / 21% ROI)
• The San Francisco Giants have hit the Team Total Over in 25 of their last 40 away games (+7.75 Units / 17% ROI)
• The San Francisco Giants have covered the Run Line in 13 of their last 19 away games (+6.75 Units / 26% ROI)
• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 27 of their last 45 games (+5.75 Units / 10% ROI)
• The San Francisco Giants have hit the Game Total Over in 25 of their last 50 away games (+4.95 Units / 9% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the Game Total Under in 19 of their last 24 games at home (+14.55 Units / 55% ROI)
• The Baltimore Orioles have hit the Team Total Under in 24 of their last 35 games at home (+11.90 Units / 29% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 22 games at home (+7.30 Units / 27% ROI)
• The Baltimore Orioles have hit the Moneyline in 21 of their last 40 games (+2.95 Units / 6% ROI)
• The Baltimore Orioles have covered the Run Line in 26 of their last 50 games at home (+0.15 Units / 0% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 4-8 against the Run Line (-8.15 Units / -43.12% ROI).

• 5-8 when betting on the Moneyline for -2.95 Units / -21.45% ROI
• 5-5 when betting on the total runs Over for -0.4 Units / -2.77% ROI
• 5-5 when betting on the total runs Under for -0.35 Units / -2.47% ROI

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 4-8 against the Run Line (-4.9 Units / -34.75% ROI).

• 6-6 when betting on the Moneyline for -1.25 Units / -8.01% ROI
• 6-6 when betting on the total runs Over for -0.75 Units / -5.66% ROI
• 6-6 when betting on the total runs Under for -0.7 Units / -5.32% ROI

Giants Keys to the Game vs. the Orioles

The Giants are just 0-8 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .030.

The Giants are just 5-8 (.385) when allowing 5 or more extra base hits this season — 4th lowest in MLB; League Avg: .520.

The Giants were just 65-6 (.915) when leading entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .956.

The Giants were 11-65 (.145) when trailing entering the 8th inning in the 2025 season — 2nd best in MLB; League Avg: .090.

Orioles Keys to the Game vs. the Giants

The Orioles were just 10-67 (.130) when they allowed 5 or more runs in the 2025 season — 4th lowest in MLB; League Avg: .202.

The Orioles were just 63-10 (.863) when leading entering the 8th inning in the 2025 season — 5th lowest in MLB; League Avg: .909.

The Orioles were just 1-77 (.013) when trailing entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .043.

The Orioles are just 1-82 (.012) when trailing entering the 9th inning since the 2025 season — tied for 2nd lowest in MLB; League Avg: .042.

Giants Hitting Stats & Trends

The Giants batted just .214 against LHP in the 2025 season — lowest in MLB.

41% of Giants hitters strikeouts have come on 95+ MPH fastballs this season — highest in MLB.

Giants hitters had an OPS of just .631 (1,623 PA’s) against LHP in the 2025 season — lowest in MLB.

The Giants are batting .291 against LHP this season — 2nd best in MLB.

Orioles Hitting Stats & Trends

Orioles hitters are slugging .591 on breaking pitches against LHP this season — best in MLB.

Orioles hitters are slugging just .362 on the first pitch of at-bats this season — 2nd lowest in MLB.

Orioles hitters have drawn walks in 12% of their PA’s against LHP this season — tied for 4th best in MLB.

The Orioles batted just .156 with two-strikes in the 2025 season — tied for 4th lowest in MLB.

Giants Pitching Stats & Trends

Opponents have a groundball rate of 49% against Giants pitchers this season — highest in MLB.

Opponents have a groundball rate of 48% against Giants pitchers since the 2023 season — highest in MLB.

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB.

Giants pitchers had a strikeout rate of just 19% with runners in scoring position in the 2025 season — 3rd lowest in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers walked 10% of batters when facing the leadoff batter in the inning in the 2025 season — 2nd highest in MLB.

Orioles pitchers have walked 11% of batters when facing the leadoff batter in the inning since the 2025 season — 2nd highest in MLB.

Orioles pitchers have walked 15% of batters when facing the leadoff batter in the inning this season — 3rd highest in MLB.

Orioles pitchers have walked 9% of batters when facing the leadoff batter in the inning since the 2024 season — 3rd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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