• The Orioles are -135 favorites vs the Giants
• Giants vs Orioles Over / Under today: 8.5 Runs
• Giants / Orioles TV Channel: NSBA | MASN

The San Francisco Giants (+110) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-135) on April 12, 2026. First pitch is scheduled for 1:35 pm in Baltimore, MD.

This season, the Giants are 6-9 against the spread (ATS), while the Orioles are 5-9 ATS.

Giants vs Orioles Starting Pitchers Today:

• Giants starting pitcher: Adrian Houser 0-1, 3.97 ERA
• Orioles starting pitcher: Cade Povich 0-0, 3.18 ERA

Giants vs. Orioles Odds, Run Line, Over/Under & Moneyline

Giants vs Orioles Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Sunday‘s MLB game with 51.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Giants vs Orioles and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Giants players for Sunday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

• Jerar Encarnacion has hit the Home Runs Over in 2 of his last 5 away games (+9.90 Units / 198% ROI)
• Matt Chapman has hit the Singles Over in 11 of his last 15 games (+8.85 Units / 59% ROI)
• Willy Adames has hit the Walks Over in 11 of his last 20 away games (+8.85 Units / 44% ROI)
• Willy Adames has hit the Hits Under in 12 of his last 20 away games (+8.05 Units / 35% ROI)
• Adrian Houser has hit the Pitching Outs Over in 14 of his last 20 games (+7.35 Units / 32% ROI)

And here are some favorite MLB player prop bets for Orioles players for Sunday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Best Bets Today:

• Gunnar Henderson has hit the Home Runs Over in 5 of his last 8 games (+22.10 Units / 276% ROI)
• Gunnar Henderson has hit the Hits Under in 15 of his last 25 games at home (+12.05 Units / 37% ROI)
• Pete Alonso has hit the Singles Over in 16 of his last 25 games at home (+9.15 Units / 36% ROI)
• Pete Alonso has hit the Walks Over in 9 of his last 15 games at home (+8.75 Units / 58% ROI)
• Gunnar Henderson has hit the Total Bases Over in 15 of his last 25 games (+7.15 Units / 27% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 24 of their last 35 away games (+12.55 Units / 30% ROI)
• The San Francisco Giants have hit the Team Total Over in 22 of their last 35 away games (+7.65 Units / 19% ROI)
• The San Francisco Giants have covered the Run Line in 14 of their last 21 away games (+6.75 Units / 23% ROI)
• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 27 of their last 45 games (+6.10 Units / 11% ROI)
• The San Francisco Giants have hit the Game Total Over in 23 of their last 45 games (+5.30 Units / 11% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the Game Total Under in 24 of their last 35 games at home (+12.75 Units / 33% ROI)
• The Baltimore Orioles have hit the Team Total Under in 24 of their last 35 games at home (+11.70 Units / 28% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 24 games at home (+7.20 Units / 24% ROI)
• The Baltimore Orioles have hit the Moneyline in 4 of their last 5 games (+2.75 Units / 42% ROI)
• The Baltimore Orioles have covered the Run Line in 3 of their last 5 games (+1.35 Units / 24% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 5-9 against the Run Line (-8.15 Units / -37.21% ROI).

• 6-9 when betting on the Moneyline for -3.1 Units / -19.44% ROI
• 7-5 when betting on the total runs Over for +1.6 Units / 9.73% ROI
• 5-7 when betting on the total runs Under for -2.75 Units / -16.62% ROI

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 5-9 against the Run Line (-4.9 Units / -29.17% ROI).

• 7-7 when betting on the Moneyline for -1.5 Units / -8.4% ROI
• 8-6 when betting on the total runs Over for +1.25 Units / 8.2% ROI
• 6-8 when betting on the total runs Under for -3.1 Units / -19.94% ROI

Giants Keys to the Game vs. the Orioles

The Giants were just 65-6 (.915) when leading entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .956.

The Giants are just 6-9 (.400) this season — tied for 3rd lowest in MLB; League Avg: .500.

The Giants were 11-65 (.145) when trailing entering the 8th inning in the 2025 season — 2nd best in MLB; League Avg: .090.

The Giants are just 1-9 (.100) when scoring 4 or fewer runs this season — 3rd lowest in MLB; League Avg: .291.

Orioles Keys to the Game vs. the Giants

The Orioles are just 0-6 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .026.

The Orioles were just 63-10 (.863) when leading entering the 8th inning in the 2025 season — 5th lowest in MLB; League Avg: .909.

The Orioles are just 2-4 (.333) after a win this season — 4th lowest in MLB; League Avg: .532.

The Orioles were just 12-51 (.190) when allowing 10 or more hits in the 2025 season — 5th lowest in MLB; League Avg: .256.

Giants Hitting Stats & Trends

The Giants batted just .214 against LHP in the 2025 season — lowest in MLB.

Giants hitters had an OPS of just .631 (1,623 PA’s) against LHP in the 2025 season — lowest in MLB.

Giants hitters have an OBP of just .274 (383 PA’s) against RHP this season — tied for 2nd lowest in MLB.

38% of Giants hitters strikeouts have come on 95+ MPH fastballs this season — highest in MLB.

Orioles Hitting Stats & Trends

Orioles hitters are slugging just .367 on the first pitch of at-bats this season — 2nd lowest in MLB.

The Orioles are batting .266 against LHP this season — tied for 4th best in MLB.

Orioles hitters slugged just .371 on the road in the 2025 season — 3rd lowest in MLB.

Orioles hitters have put 52% of balls in play to the right side of the field with runners in scoring position this season — highest in MLB.

Giants Pitching Stats & Trends

Opponents have a groundball rate of 48% against Giants pitchers since the 2023 season — highest in MLB.

Opponents have a groundball rate of 49% against Giants pitchers this season — highest in MLB.

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB.

Opponents had a groundball rate of 46% against Giants pitchers in the 2025 season — 3rd highest in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers walked 10% of batters when facing the leadoff batter in the inning in the 2025 season — 2nd highest in MLB.

Orioles pitchers have walked 11% of batters when facing the leadoff batter in the inning since the 2025 season — 2nd highest in MLB.

Orioles pitchers have walked 15% of batters when facing the leadoff batter in the inning over the past seven days (6 games) — highest in MLB.

Orioles pitchers have walked 14% of batters when facing the leadoff batter in the inning this season — 3rd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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