- The Padres are -150 favorites vs the Giants
- Giants vs Padres Over / Under today: 8 Runs
- Giants / Padres TV Channel: NSBA | PDTV
The San Francisco Giants (+125) visit Petco Park to take on the San Diego Padres (-150) on April 1, 2026. First pitch is scheduled for 4:10 pm in San Diego, CA.
This season, the Giants are against the spread (ATS), while the Padres are ATS.
Giants vs Padres Starting Pitchers Today:
- Giants starting pitcher: Adrian Houser 0-0, 0.00 ERA
- Padres starting pitcher: Nick Pivetta 0-1, 18.02 ERA
Giants vs. Padres Odds, Run Line, Over/Under & Moneyline
Giants vs Padres Prediction for Today’s Game
Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 58.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:
Best Giants Player Prop Bets Today:
- Harrison Bader has hit the Home Runs Over in 3 of his last 10 away games (+12.80 Units / 128% ROI)
- Harrison Bader has hit the Runs Over in 11 of his last 15 away games (+11.40 Units / 75% ROI)
- Willy Adames has hit the Walks Over in 12 of his last 20 away games (+11.30 Units / 56% ROI)
- Luis Arraez has hit the Singles Over in 16 of his last 20 games (+8.30 Units / 22% ROI)
- Luis Arraez has hit the Total Bases Under in 12 of his last 15 away games (+7.80 Units / 37% ROI)
And here are some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:
Best Padres Player Prop Best Bets Today:
- Gavin Sheets has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+12.30 Units / 38% ROI)
- Gavin Sheets has hit the Singles Under in 20 of his last 25 games at home (+11.75 Units / 29% ROI)
- Gavin Sheets has hit the Hits Under in 15 of his last 25 games (+9.65 Units / 39% ROI)
- Jackson Merrill has hit the Runs Over in 15 of his last 25 games (+9.55 Units / 38% ROI)
- Jackson Merrill has hit the Total Bases Over in 15 of his last 25 games (+7.95 Units / 31% ROI)
Giants Best Bets Today:
- The San Francisco Giants have hit the Team Total Over in 24 of their last 35 games (+11.95 Units / 30% ROI)
- The San Francisco Giants have covered the Run Line in 23 of their last 34 games (+10.65 Units / 23% ROI)
- The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 23 of their last 35 games (+10.10 Units / 24% ROI)
- The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 20 of their last 31 games (+7.50 Units / 20% ROI)
- The San Francisco Giants have hit the Moneyline in 20 of their last 33 games (+6.45 Units / 14% ROI)
Padres Best Bets Today:
- The San Diego Padres have hit the Game Total Under in 86 of their last 151 games (+17.30 Units / 10% ROI)
- The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 70 of their last 123 games (+10.55 Units / 7% ROI)
- The San Diego Padres have covered the Run Line in 41 of their last 76 games at home (+10.35 Units / 12% ROI)
- The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 21 of their last 32 games at home (+9.50 Units / 26% ROI)
- The San Diego Padres have hit the Team Total Over in 23 of their last 36 games at home (+7.95 Units / 18% ROI)
Giants Against the Spread (ATS) Record
Against the spread this season, the Giants are against the Run Line ( Units / ROI).
- away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
- away total over record when betting on the total runs Over for over units Units / over ROI ROI
- away total under record when betting on the total runs Under for under units Units / under ROI ROI
Padres Against the Spread (ATS) Record
Against the spread this season, the Padres are against the Run Line ( Units / ROI).
- home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
- home total over record when betting on the total runs Over for over units Units / over ROI ROI
- home total under record when betting on the total runs Under for under units Units / under ROI ROI
Giants Keys to the Game vs. the Padres
The Giants were just 65-6 (.915) when leading entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .956.
The Giants were 11-65 (.145) when trailing entering the 8th inning in the 2025 season — 2nd best in MLB; League Avg: .090.
The Giants were 12-60 (.167) when trailing entering the 7th inning in the 2025 season — tied for 4th best in MLB; League Avg: .124.
The Giants are 10-143 (.065) when trailing entering the 9th inning since the 2024 season — 5th best in MLB; League Avg: .047.
Padres Keys to the Game vs. the Giants
The Padres were 48-12 (.800) when they had 10 or more hits in the 2025 season — 5th best in MLB; League Avg: .743.
The Padres were 25-6 (.806) when they hit 2 or more home runs in the 2025 season — 5th best in MLB; League Avg: .699.
The Padres were 32-17 (.653) vs bottom 10 scoring offenses in the 2025 season Today, they face the Giants (30th in runs scored).
The Padres are 184-145 (.559) since the 2024 season — 5th best in MLB; League Avg: .500.
Giants Hitting Stats & Trends
Giants hitters are slugging just .211 this season — lowest in MLB.
56% of Giants hitters strikeouts have come on 95+ MPH fastballs this season — highest in MLB.
The Giants are batting just .212 against LHP since the 2025 season — lowest in MLB.
Giants hitters had an OPS of just .631 (1,623 PA’s) against LHP in the 2025 season — lowest in MLB.
Padres Hitting Stats & Trends
Padres hitters have struck out in just 19% of their PA’s against LHP since the 2025 season — 2nd best in MLB.
Padres hitters have struck out in just 18% of their PA’s against LHP since the 2024 season — best in MLB.
Padres hitters are slugging just .260 this season — 2nd lowest in MLB.
Padres hitters have an OPS of just .499 (77 PA’s) against RHP this season — 3rd lowest in MLB.
Giants Pitching Stats & Trends
Opponents had a groundball rate of 46% against Giants pitchers in the 2025 season — 3rd highest in MLB.
Opponents have a groundball rate of 48% against Giants pitchers since the 2023 season — highest in MLB.
Opponents have a groundball rate of 46% against Giants pitchers since the 2025 season — 3rd highest in MLB.
The Giants allowed 1.02 runs per game (165/161) in late innings in the 2025 season — best in MLB.
Padres Pitching Stats & Trends
Padres pitchers had a strikeout rate of 24% in the 2025 season — tied for 4th best in MLB.
Padres pitchers have a strikeout rate of 45% with two-strikes since the 2025 season — 5th best in MLB.
Opponents batted just .225 against Padres pitchers in the 2025 season — best in MLB.
Padres pitchers allowed a slugging percentage of just .370 in the 2025 season — best in MLB.
More MLB Reading:
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