• The Red Sox are -190 favorites vs the Giants
• Giants vs Red Sox Over / Under today: 7.5 Runs
• Giants / Red Sox TV Channel: NSBA | NESN

The San Francisco Giants (+155) visit Fenway Park to take on the Boston Red Sox (-190) on August 21, 2026. First pitch is scheduled for 7:10 pm in Boston, MA.

This season, the Giants are 52-75 against the spread (ATS), while the Red Sox are 62-61 ATS.

Giants vs Red Sox Starting Pitchers Today:

• Giants starting pitcher: Logan Webb 8-7, 3.49 ERA
• Red Sox starting pitcher: Sonny Gray 15-3, 2.67 ERA

Giants vs. Red Sox Odds, Run Line, Over/Under & Moneyline

Giants vs Red Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Friday‘s MLB game with 63.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Giants players for Friday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

• Osleivis Basabe has hit the Home Runs Over in 3 of his last 8 away games (+24.00 Units / 300% ROI)
• Drew Cavanaugh has hit the Hits Under in 16 of his last 25 games (+7.95 Units / 29% ROI)
• Willy Adames has hit the Total Bases Over in 15 of his last 20 games (+7.50 Units / 25% ROI)
• Christian Koss has hit the Hits Runs and RBIs Under in 11 of his last 15 away games (+7.40 Units / 40% ROI)
• Willy Adames has hit the Runs Over in 13 of his last 25 away games (+7.10 Units / 27% ROI)

And here are some favorite MLB player prop bets for Red Sox players for Friday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Best Bets Today:

• Mickey Gasper has hit the Home Runs Over in 3 of his last 4 games (+22.50 Units / 562% ROI)
• Wilyer Abreu has hit the Walks Over in 12 of his last 15 games (+16.70 Units / 111% ROI)
• Andruw Monasterio has hit the Hits Runs and RBIs Over in 18 of his last 25 games (+11.65 Units / 39% ROI)
• Andruw Monasterio has hit the Total Bases Over in 18 of his last 25 games (+11.60 Units / 35% ROI)
• Caleb Durbin has hit the Runs Over in 13 of his last 20 games (+10.95 Units / 54% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 20 of their last 40 games (+8.75 Units / 19% ROI)
• The San Francisco Giants have hit the Team Total Under in 30 of their last 50 away games (+8.10 Units / 14% ROI)
• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 9 of their last 12 games (+6.20 Units / 43% ROI)
• The San Francisco Giants have hit the Game Total Over in 19 of their last 40 away games (+3.70 Units / 8% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 13 away games (+2.65 Units / 17% ROI)

Red Sox Best Bets Today:

• The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Over in 34 of their last 50 games (+16.80 Units / 28% ROI)
• The Boston Red Sox have hit the Moneyline in 36 of their last 50 games (+16.65 Units / 23% ROI)
• The Boston Red Sox have hit the Team Total Over in 34 of their last 50 games (+16.40 Units / 28% ROI)
• The Boston Red Sox have covered the Run Line in 30 of their last 50 games (+15.65 Units / 26% ROI)
• The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 32 of their last 50 games (+12.60 Units / 22% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 60-65 against the Run Line (-20.45 Units / -11.7% ROI).

• 52-75 when betting on the Moneyline for -20.3 Units / -14.36% ROI
• 57-58 when betting on the total runs Over for -6.85 Units / -4.89% ROI
• 58-57 when betting on the total runs Under for -4.5 Units / -3.23% ROI

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 62-61 against the Run Line (+2.75 Units / 1.74% ROI).

• 68-59 when betting on the Moneyline for -5.5 Units / -3.33% ROI
• 59-64 when betting on the total runs Over for -12.1 Units / -8.62% ROI
• 64-59 when betting on the total runs Under for -1 Units / -0.72% ROI

Red Sox vs Giants Home Run Prop Bets Today

Red Sox vs Giants Total Hits Prop Bets Today

Red Sox vs Giants Strikeout Prop Bets Today

Giants Keys to the Game vs. the Red Sox

The Giants are just 1-56 (.018) when trailing entering the 7th inning this season — lowest in MLB.

The Giants are just 1-59 (.017) when trailing entering the 8th inning this season — tied for lowest in MLB.

The Giants are just 6-23 (.207) when allowing 2 or more home runs this season — 4th lowest in MLB.

The Giants are just 21-31 (.404) after a win this season — 4th lowest in MLB.

Red Sox Keys to the Game vs. the Giants

The Red Sox are 60-2 (.968) when leading entering the 8th inning this season — 4th best in MLB.

The Red Sox are just 4-9 (.308) when tied entering the 8th inning this season — 4th lowest in MLB.

The Red Sox are 131-6 (.956) when leading entering the 8th inning since the 2025 season — best in MLB.

The Red Sox are 137-3 (.979) when leading entering the 9th inning since the 2025 season — 3rd best in MLB.

Giants Hitting Stats & Trends

The Giants are just 1-56 (.018) when trailing entering the 7th inning this season — lowest in MLB.

The Giants are just 1-59 (.017) when trailing entering the 8th inning this season — tied for lowest in MLB.

The Giants are just 17-34 (-31.4% ROI) when slight moneyline underdogs (+101 to +149) this season — tied for 2nd lowest in MLB.

The Giants are just 6-23 (.207) when allowing 2 or more home runs this season — 4th lowest in MLB.

Red Sox Hitting Stats & Trends

The Red Sox are just 18-28 (.391) against the run line (-17.1% ROI) vs the bottom 10 runs allowed teams this season Today, they face the Giants (20th fewest runs allowed).

The Red Sox are 60-2 (.968) when leading entering the 8th inning this season — 4th best in MLB.

Games involving the Red Sox went UNDER in 59% of their games (13.5% ROI) vs bottom 10 scoring offenses this season Today, they face the Giants (24th in runs scored).

Games involving the Red Sox went UNDER in 56% of their games (11.9% ROI) when slight moneyline favorites (-101 to -149) this season — 5th highest in MLB.

Giants Pitching Stats & Trends

Giants pitchers have walked 50 of 463 batters (11%) over the last 14 days (12 games) — 2nd highest in MLB; League Avg: 9%.

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB.

Giants pitchers have walked 70 of 652 batters (11%) this month (17 games) — tied for 2nd highest in MLB; League Avg: 9%.

Opponents have a groundball rate of 45% against Giants pitchers this month (17 games) — 5th highest in MLB; League Avg: 42%.

Red Sox Pitching Stats & Trends

Red Sox pitchers have walked 34 of 463 batters (7%) over the last 14 days (13 games) — 2nd best in MLB; League Avg: 9%.

Opponents have a groundball rate of 47% against Red Sox pitchers this month (18 games) — 2nd highest in MLB; League Avg: 42%.

Red Sox pitchers have walked 54 of 667 batters (8%) this month (18 games) — 5th best in MLB; League Avg: 9%.

Red Sox pitchers have walked 6 of 113 batters (5%) when facing the leadoff batter in the inning over the last 14 days (13 games) — 5th best in MLB; League Avg: 8%.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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