Guardians vs Angels Prediction, Odds & Player Prop Bets Today – MLB, Aug 25

Los Angeles Angels starting pitcher Josรฉ Soriano throws in the first inning of a baseball game against the Cincinnati Reds, Sunday, April 21, 2024, in Cincinnati.
(AP Photo/Carolyn Kaster)
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  • The Guardians are -140 favorites vs the Angels
  • Guardians vs Angels Over / Under today: 7.5 Runs
  • Guardians / Angels TV Channel: GDTV | ABTV

The Cleveland Guardians (-140) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (+115) on August 25, 2026. First pitch is scheduled for 9:38 pm in Anaheim, CA.

This season, the Guardians are 66-66 against the spread (ATS), while the Angels are 65-66 ATS.

Guardians vs Angels Starting Pitchers Today:

  • Guardians starting pitcher: Gavin Williams 12-7, 3.73 ERA
  • Angels starting pitcher: Walbert Urena 8-9, 2.79 ERA

Guardians vs. Angels Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians-1.5 +120O 7.5 -125-140
Angels +1.5 -145U 7.5 +105+115

Guardians vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Tuesday‘s MLB game with 59.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Tuesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Jo Adell has hit the Home Runs Over in 4 of his last 10 games (+11.90 Units / 119% ROI)
  • Nathaniel Lowe has hit the Walks Under in 14 of his last 15 away games (+11.20 Units / 31% ROI)
  • Brayan Rocchio has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+11.15 Units / 32% ROI)
  • Angel Martinez has hit the Total Bases Over in 12 of his last 15 games (+10.60 Units / 57% ROI)
  • Brayan Rocchio has hit the Runs Under in 20 of his last 25 games (+9.90 Units / 19% ROI)

And here are some favorite MLB player prop bets for Angels players for Tuesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

  • Walbert Urena has hit the Hits Allowed Under in 14 of his last 20 games (+7.65 Units / 34% ROI)
  • Walbert Urena has hit the Strikeouts Over in 11 of his last 15 games (+7.05 Units / 36% ROI)
  • Walbert Urena has hit the Earned Runs Under in 14 of his last 20 games (+6.00 Units / 22% ROI)
  • Walbert Urena has hit the Pitching Outs Over in his last 4 games at home (+4.15 Units / 98% ROI)
  • Walbert Urena has hit the Walks Allowed Under in 4 of his last 5 games at home (+3.00 Units / 45% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 32 of their last 50 away games (+11.85 Units / 21% ROI)
  • The Cleveland Guardians have hit the Moneyline in 25 of their last 45 away games (+6.45 Units / 13% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 29 of their last 50 away games (+6.10 Units / 11% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 20 games (+5.35 Units / 22% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in their last 5 games (+5.05 Units / 86% ROI)
  • The Los Angeles Angels have hit the Game Total Under in 30 of their last 40 games (+20.00 Units / 45% ROI)
  • The Los Angeles Angels have hit the Team Total Under in 35 of their last 50 games (+19.05 Units / 33% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 22 of their last 45 games at home (+8.65 Units / 16% ROI)
  • The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 27 of their last 45 games at home (+7.00 Units / 13% ROI)
  • The Los Angeles Angels have covered the Run Line in 9 of their last 13 games (+3.65 Units / 19% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 63-68 against the Run Line (-9.65 Units / -5.72% ROI).

  • 66-66 when betting on the Moneyline for -6.85 Units / -4.22% ROI
  • 61-70 when betting on the total runs Over for -15.15 Units / -10.54% ROI
  • 70-61 when betting on the total runs Under for +2.2 Units / 1.5% ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 65-66 against the Run Line (-20.9 Units / -11.47% ROI).

  • 52-80 when betting on the Moneyline for -19.2 Units / -13.67% ROI
  • 53-76 when betting on the total runs Over for -30.05 Units / -20.67% ROI
  • 76-53 when betting on the total runs Under for +18.35 Units / 12.64% ROI

Angels vs Guardians Home Run Prop Bets Today

Yes
Mike Trout +350
Zachary Neto +390
Jo Adell +400
Jose Ramirez +450
Chase DeLauter +475

Angels vs Guardians Total Hits Prop Bets Today

Over Under
Steven Kwan 0.5 -235 0.5 +170
Chase DeLauter 0.5 -235 0.5 +175
Jose Ramirez 0.5 -210 0.5 +150
Angel Genao 0.5 -190 0.5 +140
Nathaniel Lowe 0.5 -165 0.5 +125

Angels vs Guardians Strikeout Prop Bets Today

Over Under
Gustavo Campero 0.5 -235 0.5 +175
Nathaniel Lowe 0.5 -225 0.5 +165
Patrick Bailey 0.5 -225 0.5 +165
Travis Bazzana 0.5 -185 0.5 +135
Walbert Urena 3.5 -165 3.5 +125

Guardians Keys to the Game vs. the Angels

The Guardians are just 2-60 (.032) when trailing entering the 9th inning this season — 5th lowest in MLB.

The Guardians are just 5-49 (.093) when trailing entering the 7th inning this season — 4th lowest in MLB.

The Guardians are 116-10 (.921) when leading entering the 7th inning since the 2025 season — 2nd best in MLB.

The Guardians are 17-12 (.586) when tied entering the 8th inning since the 2025 season — tied for 4th best in MLB.

Angels Keys to the Game vs. the Guardians

The Angels are just 4-32 (.111) when allowing 10 or more hits this season — lowest in MLB.

The Angels are just 50-74 (.403) when allowing 5 or more extra base hits this season — lowest in MLB.

The Angels are just 13-7 (.650) when they’ve had 5 or more XBH this season — 3rd lowest in MLB.

The Angels are just 5-15 (.250) when tied entering the 7th inning this season — 2nd lowest in MLB.

Guardians hitters are slugging just .282 against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB.

The Guardians are batting just .221 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

Guardians hitters have an OPS of just .544 (333 PA’s) against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB.

The Guardians are hitting just .177 against pitchers who have thrown at least 80 pitches in the game this season — lowest in MLB.

Angels hitters are slugging just .333 at home this season — lowest in MLB.

Angels hitters have struck out in 25% of their PA’s against RHP this season — 2nd highest in MLB.

Angels hitters have an OPS of just .631 (2,400 PA’s) at home this season — lowest in MLB.

Angels hitters have an OBP of just .298 (2,400 PA’s) at home this season — lowest in MLB.

Opponents have a miss rate of 27% against Guardians pitchers this season — tied for 4th best in MLB.

Guardians pitchers have a strikeout rate of 45% with two-strikes this season — tied for 4th best in MLB.

Guardians pitchers have a strikeout rate of 27% in late innings this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 3rd best in MLB.

Angels pitchers have walked 11% of batters this season — tied for highest in MLB.

Angels pitchers have won only 15% of games in which they have allowed their opponent to score in three different innings this season — lowest in MLB.

Opponents have a miss rate of 28% against Angels pitchers this season — 2nd best in MLB.

Angels pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.