• The Guardians are -145 favorites vs the Angels
• Guardians vs Angels Over / Under today: 8.5 Runs
• Guardians / Angels TV Channel: GDTV | ABTV

The Cleveland Guardians (-145) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (+118) on August 26, 2026. First pitch is scheduled for 4:07 pm in Anaheim, CA.

This season, the Guardians are against the spread (ATS), while the Angels are ATS.

Guardians vs Angels Starting Pitchers Today:

• Guardians starting pitcher: Joey Cantillo 9-7, 3.74 ERA
• Angels starting pitcher: Grayson Rodriguez 4-5, 6.41 ERA

Guardians vs. Angels Odds, Run Line, Over/Under & Moneyline

Guardians vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Wednesday‘s MLB game with 58.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Guardians vs Angels and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Angel Martinez has hit the Total Bases Over in 13 of his last 15 games (+13.15 Units / 70% ROI)
• Steven Kwan has hit the Singles Over in 20 of his last 25 games (+11.80 Units / 30% ROI)
• Nathaniel Lowe has hit the Walks Under in 14 of his last 15 away games (+11.20 Units / 31% ROI)
• Angel Martinez has hit the Hits Over in 13 of his last 15 games (+11.00 Units / 40% ROI)
• Brayan Rocchio has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+10.90 Units / 31% ROI)

And here are some favorite MLB player prop bets for Angels players for Wednesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

• Moisés Ballesteros has hit the Runs Under in 21 of his last 25 games (+12.35 Units / 23% ROI)
• Moisés Ballesteros has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+11.85 Units / 35% ROI)
• Moisés Ballesteros has hit the Hits Under in 14 of his last 20 games at home (+10.95 Units / 48% ROI)
• Moisés Ballesteros has hit the Total Bases Under in 15 of his last 20 games at home (+9.75 Units / 35% ROI)
• Zach Neto has hit the Singles Over in 7 of his last 8 games (+8.35 Units / 104% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Game Total Under in 32 of their last 50 away games (+11.75 Units / 21% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 21 games (+6.35 Units / 25% ROI)
• The Cleveland Guardians have hit the Moneyline in 25 of their last 45 away games (+6.30 Units / 12% ROI)
• The Cleveland Guardians have hit the Team Total Under in 29 of their last 50 away games (+6.10 Units / 11% ROI)
• The Cleveland Guardians have covered the Run Line in 14 of their last 22 away games (+5.05 Units / 17% ROI)

Angels Best Bets Today:

• The Los Angeles Angels have hit the Game Total Under in 30 of their last 40 games (+19.90 Units / 45% ROI)
• The Los Angeles Angels have hit the Team Total Under in 34 of their last 50 games (+16.95 Units / 29% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 23 of their last 45 games at home (+9.85 Units / 18% ROI)
• The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 27 of their last 45 games at home (+7.00 Units / 13% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Under in 4 of their last 5 games (+2.70 Units / 47% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Angels vs Guardians Home Run Prop Bets Today

Angels vs Guardians Total Hits Prop Bets Today

Angels vs Guardians Strikeout Prop Bets Today

Guardians Keys to the Game vs. the Angels

The Guardians are 116-10 (.921) when leading entering the 7th inning since the 2025 season — 2nd best in MLB.

The Guardians are 38-5 (.884) when they’ve had 5 or more XBH since the 2025 season — 4th best in MLB.

The Guardians are 17-12 (.586) when tied entering the 8th inning since the 2025 season — 4th best in MLB.

The Guardians are 65-119 (.353) when scoring 4 or fewer runs since the 2025 season — 2nd best in MLB.

Angels Keys to the Game vs. the Guardians

The Angels are just 4-33 (.108) when allowing 10 or more hits this season — lowest in MLB.

The Angels are just 19-33 (.365) after a win this season — 2nd lowest in MLB.

The Angels are just 1-62 (.016) when trailing entering the 9th inning this season — tied for lowest in MLB.

The Angels are just 7-33 (.175) when allowing 2 or more home runs this season — lowest in MLB.

Guardians Hitting Stats & Trends

Guardians hitters are slugging just .370 this season — lowest in MLB.

Guardians hitters are slugging just .351 against LHP this season — 3rd lowest in MLB.

Guardians hitters have an OPS of just .670 (1,521 PA’s) against LHP this season — 4th lowest in MLB.

The Guardians are batting just .228 against LHP this season — 3rd lowest in MLB.

Angels Hitting Stats & Trends

Angels hitters have struck out in 25% of their PA’s against RHP this season — 2nd highest in MLB.

Angels hitters are slugging just .337 at home this season — lowest in MLB.

Angels hitters have an OPS of just .635 (2,445 PA’s) at home this season — lowest in MLB.

Angels hitters are slugging just .373 against RHP this season — lowest in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 25% this season — 3rd best in MLB.

Guardians pitchers have a strikeout rate of 45% with two-strikes this season — tied for 4th best in MLB.

Guardians pitchers have a strikeout rate of 29% in close and late situations this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% with runners in scoring position this season — 2nd best in MLB.

Angels Pitching Stats & Trends

Opponents have a miss rate of 28% against Angels pitchers this season — 2nd best in MLB.

Angels pitchers have walked 11% of batters this season — highest in MLB.

Angels pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

Angels pitchers have won only 14% of games in which they have allowed their opponent to score in three different innings this season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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