Guardians vs Athletics Prediction, Odds & Player Prop Bets Today – MLB, May 1

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  • The Guardians are -110 favorites vs the Athletics
  • Guardians vs Athletics Over / Under today: 9.5 Runs
  • Guardians / Athletics TV Channel: GDTV | NSCA

The Cleveland Guardians (-110) visit Sutter Health Park to take on the Athletics (-110) on May 1, 2026. First pitch is scheduled for 9:40 pm in Sacramento, CA.

This season, the Guardians are 16-16 against the spread (ATS), while the Athletics are 20-11 ATS.

Guardians vs Athletics Starting Pitchers Today:

  • Guardians starting pitcher: , ERA
  • Athletics starting pitcher: , ERA

Guardians vs. Athletics Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians-1.5 +150O 9.5 -120-110
Athletics +1.5 -185U 9.5 +100-110

Guardians vs Athletics Prediction for Today’s Game

Based on recent trends the model predicts the will win Friday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • player high – away 

And here are some favorite MLB player prop bets for Athletics players for Friday‘s game, looking at profitable historical betting trends:

Best Athletics Player Prop Best Bets Today:

  • player  high – home
  • team high – away
  • team high – home

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 16-16 against the Run Line (-0.75 Units / -1.86% ROI).

  • 16-16 when betting on the Moneyline for +0.7 Units / 1.89% ROI
  • 15-17 when betting on the total runs Over for -3.5 Units / -9.93% ROI
  • 17-15 when betting on the total runs Under for +0.5 Units / 1.41% ROI

Athletics Against the Spread (ATS) Record

Against the spread this season, the Athletics are 20-11 against the Run Line (+5.75 Units / 12.99% ROI).

  • 17-14 when betting on the Moneyline for +5.25 Units / 15.53% ROI
  • 14-16 when betting on the total runs Over for -3.4 Units / -9.99% ROI
  • 16-14 when betting on the total runs Under for +0.75 Units / 2.2% ROI

Athletics vs Guardians Home Run Prop Bets Today

Yes
Jose Ramirez +350
Nick Kurtz +350
Brent Rooker +390
Kyle Manzardo +400
Chase DeLauter +400

Athletics vs Guardians Total Hits Prop Bets Today

Over Under
Angel Martinez 0.5 -210 0.5 +155
Kyle Manzardo 0.5 -190 0.5 +140
Darell Hernaiz 0.5 -175 0.5 +130
Brent Rooker 0.5 -165 0.5 +125
Daniel Schneemann 0.5 -165 0.5 +125

Athletics vs Guardians Strikeout Prop Bets Today

Over Under
Kyle Manzardo 0.5 -275 0.5 +195
Daniel Schneemann 0.5 -275 0.5 +200
Travis Bazzana 0.5 -235 0.5 +175
Bo Naylor 0.5 -200 0.5 +145
Tyler Soderstrom 0.5 -200 0.5 +145

Guardians Keys to the Game vs. the Athletics

Athletics Keys to the Game vs. the Guardians

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.