• The Blue Jays are -145 favorites vs the Guardians
• Guardians vs Blue Jays Over / Under today: 7.5 Runs
• Guardians / Blue Jays TV Channel: FS1 | GDTV | RSN1

The Cleveland Guardians (+120) visit Rogers Centre to take on the Toronto Blue Jays (-145) on April 25, 2026. First pitch is scheduled for 3:07 pm in Toronto, ON.

This season, the Guardians are against the spread (ATS), while the Blue Jays are ATS.

Guardians vs Blue Jays Starting Pitchers Today:

• Guardians starting pitcher: Joey Cantillo 1-0, 3.24 ERA
• Blue Jays starting pitcher: Kevin Gausman 1-1, 2.49 ERA

Guardians vs. Blue Jays Odds, Run Line, Over/Under & Moneyline

Guardians vs Blue Jays Prediction for Today’s Game

Based on recent trends the model predicts the Blue Jays will win Saturday‘s MLB game with 57.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Guardians vs Blue Jays and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Guardians players for Saturday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Daniel Schneemann has hit the Home Runs Over in 3 of his last 8 games (+18.50 Units / 231% ROI)
• Daniel Schneemann has hit the Hits Runs and RBIs Over in 13 of his last 15 games (+11.30 Units / 60% ROI)
• Daniel Schneemann has hit the Total Bases Over in 13 of his last 15 games (+11.00 Units / 56% ROI)
• Daniel Schneemann has hit the Hits Over in 13 of his last 15 games (+10.50 Units / 49% ROI)
• Daniel Schneemann has hit the Runs Over in 7 of his last 8 games (+10.05 Units / 126% ROI)

And here are some favorite MLB player prop bets for Blue Jays players for Saturday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Best Bets Today:

• Ernie Clement has hit the Hits Over in 17 of his last 20 games at home (+13.90 Units / 37% ROI)
• Kazuma Okamoto has hit the Home Runs Over in 2 of his last 5 games (+9.90 Units / 198% ROI)
• Ernie Clement has hit the Hits Runs and RBIs Over in 17 of his last 25 games at home (+9.80 Units / 36% ROI)
• Vladimir Guerrero Jr has hit the Singles Over in 18 of his last 25 games (+8.95 Units / 27% ROI)
• Ernie Clement has hit the Total Bases Over in 13 of his last 20 games at home (+8.00 Units / 33% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Moneyline in 30 of their last 50 away games (+17.15 Units / 32% ROI)
• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 28 of their last 40 away games (+14.65 Units / 30% ROI)
• The Cleveland Guardians have covered the Run Line in 30 of their last 50 games (+13.75 Units / 22% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 20 of their last 40 away games (+10.45 Units / 25% ROI)
• The Cleveland Guardians have hit the Team Total Over in 15 of their last 21 away games (+7.60 Units / 29% ROI)

Blue Jays Best Bets Today:

• The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 19 of their last 25 games (+13.30 Units / 44% ROI)
• The Toronto Blue Jays have hit the Team Total Over in 28 of their last 45 games at home (+9.40 Units / 18% ROI)
• The Toronto Blue Jays have hit the Game Total Over in 25 of their last 45 games (+4.40 Units / 9% ROI)
• The Toronto Blue Jays have covered the 1st Five Innings (F5) Run Line in 15 of their last 25 games at home (+3.20 Units / 11% ROI)
• The Toronto Blue Jays have hit the 1st Five Innings (F5) Moneyline in 15 of their last 30 games at home (+2.90 Units / 6% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Guardians Keys to the Game vs. the Blue Jays

The Guardians are just 3-11 (.214) after a win this season — lowest in MLB; League Avg: .524.

The Guardians are 38-4 (.884) when they’ve had 10 or more hits since the 2025 season — 2nd best in MLB; League Avg: .746.

The Guardians are 27-3 (.900) when they’ve had 5 or more XBH since the 2025 season — 3rd best in MLB; League Avg: .798.

The Guardians are 50-44 (.526) on the road since the 2025 season — 4th best in MLB; League Avg: .458.

Blue Jays Keys to the Game vs. the Guardians

The Blue Jays are 14-65 (.177) when trailing entering the 8th inning since the 2025 season — best in MLB; League Avg: .092.

The Blue Jays are 78-6 (.929) when scoring 5 or more runs since the 2025 season — best in MLB; League Avg: .793.

The Blue Jays are 7-69 (.092) when trailing entering the 9th inning since the 2025 season — best in MLB; League Avg: .044.

The Blue Jays are 17-62 (.215) when trailing entering the 7th inning since the 2025 season — tied for best in MLB; League Avg: .126.

Guardians Hitting Stats & Trends

The Guardians are batting just .226 since the 2025 season — 2nd lowest in MLB.

Guardians hitters have struck out in 32% of their PA’s in righty-righty matchups since the 2025 season — highest in MLB.

Guardians hitters have struck out in just 18% of their PA’s against LHP this season — 3rd best in MLB.

The Guardians are batting just .194 in righty-righty matchups since the 2025 season — lowest in MLB.

Blue Jays Hitting Stats & Trends

Blue Jays hitters have struck out in just 18% of their PA’s against RHP since the 2025 season — best in MLB.

Blue Jays hitters have struck out in just 18% of their PA’s since the 2025 season — best in MLB.

The Blue Jays are batting .183 on pitches out of the zone since the 2025 season — best in MLB.

Blue Jays hitters have struck out in just 18% of their PA’s this season — best in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 36% in close and late situations this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 2nd best in MLB.

Guardians pitchers have an ERA of 2.51 (498.1 IP) against division opponents since the 2025 season — best in MLB.

Guardians pitchers have a strikeout rate of 23% with runners in scoring position since the 2025 season — tied for 4th best in MLB.

Blue Jays Pitching Stats & Trends

Blue Jays pitchers have a strikeout rate of 26% this season — best in MLB.

Blue Jays pitchers have a strikeout rate of 47% with two-strikes this season — best in MLB.

Blue Jays pitchers have a strikeout rate of 31% versus the bottom of the order this season — best in MLB.

Blue Jays pitchers have a strikeout rate of 27% versus hitters not batting 3-4-5 in the order this season — best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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