Guardians vs Giants Prediction, Odds & Player Prop Bets Today – MLB, Sep 12

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Sep 12, 2023, 3:30 PM
  • The Giants are -185 favorites vs the Guardians
  • Guardians starting pitcher: Cal Quantrill
  • Giants starting pitcher: Sean Manaea
  • Watch the game on MLB Network

The Cleveland Guardians (+150) visit Oracle Park to take on the San Francisco Giants (-185) on Tuesday, September 12, 2023. First pitch is scheduled for 9:45pm EDT in San Francisco.

The Giants are the betting favorite in this game, with the run line sitting at -1.5 (+110).

The Guardians vs Giants Over/Under is 8.5 total runs for the game.

This season, the Guardians are 68-77 against the spread (ATS), while the Giants are 68-76 ATS.

Guardians vs. Giants Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians+1.5 -135O 8.5 -110+150
Giants -1.5 +110U 8.5 -110-185

Guardians vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Giants will win Tuesday‘s MLB matchup with 60.5% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Guardians and Giants and up-to-date player injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Tuesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Cal Quantrill has hit the Strikeouts Under in 13 of his last 15 games (+10.45 Units / 43% ROI)
  • Tanner Bibee has hit the Earned Runs Under in 16 of his last 21 games (+9.50 Units / 36% ROI)
  • Gabriel Arias has hit the Singles Under in 11 of his last 12 away games (+9.40 Units / 46% ROI)
  • Jose Ramirez has hit the Runs Under in 31 of his last 46 games (+9.40 Units / 15% ROI)
  • Jose Ramirez has hit the RBIs Under in 31 of his last 41 games (+9.20 Units / 10% ROI)

And here are some favorite MLB player prop bets for Giants players for Tuesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

  • Logan Webb has hit the Pitching Outs Over in 20 of his last 28 games (+12.45 Units / 35% ROI)
  • Paul DeJong has hit the Hits Runs and RBIs Under in 14 of his last 16 games at home (+11.90 Units / 49% ROI)
  • Casey Schmitt has hit the Singles Under in 16 of his last 19 games at home (+11.90 Units / 44% ROI)
  • Thairo Estrada has hit the Hits Over in 18 of his last 26 games (+11.85 Units / 25% ROI)
  • Paul DeJong has hit the Total Bases Under in 13 of his last 15 games at home (+11.75 Units / 72% ROI)

Giants vs Guardians Home Run Prop Bets Today

Over Under
Brandon Crawford 0.5 +750 0.5 -3000
Tyler Freeman 0.5 +1000 0.5
Mike Yastrzemski 0.5 +425 0.5 -900
LaMonte Wade Jr 0.5 +625 0.5 -2000
Steven Kwan 0.5 +1400 0.5

Giants vs Guardians Total Hits Prop Bets Today

Over Under
Brandon Crawford 0.5 -150 0.5 +115
Tyler Freeman 0.5 -275 0.5 +195
Mike Yastrzemski 0.5 -225 0.5 +165
LaMonte Wade Jr 0.5 -185 0.5 +140
Steven Kwan 1.5 +165 1.5 -225

Giants vs Guardians RBI Prop Bets Today

Over Under
Brandon Crawford 0.5 +230 0.5 -350
Tyler Freeman 0.5 +210 0.5 -275
Mike Yastrzemski 0.5 +185 0.5 -250
LaMonte Wade Jr 0.5 +195 0.5 -275
Steven Kwan 0.5 +240 0.5 -350

Giants vs Guardians Strikeout Prop Bets Today

Over Under
Sean Manaea 3.5 -125 3.5 -105
Cal Quantrill 3.5 -150 3.5 +115
  • The Cleveland Guardians have hit the Game Total Under in 77 of their last 129 games (+23.50 Units / 17% ROI)
  • The Cleveland Guardians have covered the Run Line in 57 of their last 103 games (+9.65 Units / 7% ROI)
  • The Cleveland Guardians have hit the Team Total Over in 19 of their last 31 away games (+4.99 Units / 14% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 7 of their last 11 away games (+2.75 Units / 21% ROI)
  • The Cleveland Guardians have hit the Moneyline in 7 of their last 14 away games (+1.35 Units / 9% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 59 of their last 97 games (+16.53 Units / 14% ROI)
  • The San Francisco Giants have hit the Game Total Under in 74 of their last 130 games (+16.50 Units / 12% ROI)
  • The San Francisco Giants have hit the Team Total Under in 41 of their last 67 games (+12.13 Units / 16% ROI)
  • The San Francisco Giants have hit the Moneyline in 25 of their last 39 games at home (+7.65 Units / 13% ROI)
  • The San Francisco Giants have covered the Run Line in 34 of their last 65 games at home (+6.20 Units / 8% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this MLB season, the Guardians have gone 73-72 against the Run Line (-2.6 Units / -1.41% ROI).

  • 68-77 when betting on the Moneyline for -19.3 Units / -10.67% ROI
  • 58-83 when betting on the total runs Over for -34 Units / -21.23% ROI
  • 83-58 when betting on the total runs Under for +19.65 Units / 12.34% ROI

Giants Against the Spread (ATS) Record

Against the spread this MLB season, the Giants have gone 68-76 against the Run Line (-16.25 Units / -8.71% ROI).

  • 74-70 when betting on the Moneyline for -7.25 Units / -3.88% ROI
  • 62-79 when betting on the total runs Over for -25.95 Units / -16.2% ROI
  • 79-62 when betting on the total runs Under for +11.65 Units / 7.43% ROI

Carlos Rodon allowed an OPS of just .571 (710 PA’s) in 2022 — 4th best among qualified SPs in MLB; League Avg: .664 — 93rd Percentile.

Carlos Rodon had a strikeout rate of 33% (237/710) in 2022 — best among qualified SPs in MLB; League Avg: 23% — 100th Percentile.

Opponents had a groundball rate of just 35% (148/417) against Carlos Rodon in 2022 — 2nd lowest among qualified SPs in MLB; League Avg: 44% — fourth Percentile.

Carlos Rodon elevated 49% of his pitches (296/606) when ahead in the count in 2022 — highest among qualified SPs in MLB; League Avg: 29% — 100th Percentile.

Giants Starting Pitcher Stats & Trends

Sean Manaea has allowed a slugging percentage of .786 (22 Total Bases / 28 ABs) on low fastballs this season — 2nd highest among qualified RPs in MLB; League Avg: .408 — second Percentile.

Right-handed hitters have a line drive rate of 31% (51/165) against Sean Manaea this season — 5th highest among qualified RPs in MLB*; League Avg: 23% — fifth Percentile.

Sean Manaea has thrown elevated pitches 50% of the time (164/330) when behind in the count this season — highest among qualified RPs in MLB; League Avg: 30% — 100th Percentile.

Opponents have a chase percentage of just 20% (35/172) against Sean Manaea in late innings since last season — lowest in MLB among starting pitchers with at least 122 total IP; League Avg: 31% — first Percentile.

Guardians Keys to the Game vs. the Giants

The Guardians are 33-107 (.236) when trailing entering the 7th inning since last season — best in MLB; League Avg: .130.

The Guardians are just 5-15 (.250) when tied entering the 8th inning this season — 2nd lowest in MLB; League Avg: .500.

The Guardians are 7-63 (.100) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .053.

The Guardians are just 5-15 (.250) when tied entering the 7th inning this season — lowest in MLB; League Avg: .500.

Giants Keys to the Game vs. the Guardians

The Giants are 31-29 (.517) after a win as underdogs since last season — tied for best in MLB; League Avg: .416.

The Giants are 18-12 (.600) after a road win this season — tied for 4th best in MLB; League Avg: .496.

The Giants are 19-15 (.559) after a win as underdogs this season — 5th best in MLB; League Avg: .433.

The Giants are just 14-26 (.350) after a road loss this season — 5th lowest in MLB; League Avg: .464.

team hitters – away

Giants hitters have 892 strikeouts in 3,547 PA’s (25%) against LHP since last season — tied for highest in MLB; League Avg: 22%.

The Giants are batting just .152 with two-strikes this season — 2nd lowest in MLB; League Avg: .172.

Giants hitters have drawn 110 walks in 1,615 PA’s (7%) against LHP this season — 3rd lowest in MLB; League Avg: 8%.

Giants hitters are slugging just .244 with two-strikes this season — 2nd lowest in MLB; League Avg: .274.

Guardians pitchers have allowed an average Exit Velocity of 89.6 MPH (3,654 batted balls) this season — 3rd highest in MLB; League Avg: 89.1.

Guardians pitchers have an ERA of 3.51 (407.1 IP) against division opponents this season — 4th best in MLB; League Avg: 4.32.

Guardians pitchers have allowed 138 stolen bases this season — tied for 2nd most in MLB.

Guardians pitchers walked 88 of 1,460 batters (6%) when facing the leadoff batter in the inning in 2022 — 3rd best in MLB; League Avg: 7%.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers this season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 48% against Giants pitchers since the 2021 season — highest in MLB; League Avg: 43%.

Giants pitchers have walked 365 of 5,368 batters (7%) this season — tied for best in MLB; League Avg: 9%.

Giants vs. Guardians Injuries Tonight That May Affect Prop Bets 

  • Roberto Pérez (Giants): Shoulder, D60
  • Mark Mathias (Giants): Shoulder, D60
  • Patrick Bailey (Giants): Concussion, D7
  • Thomas Szapucki (Giants): Arm, D60
  • Cole Waites (Giants): Elbow, D60
  • Anthony DeSclafani (Giants): Elbow, D60
  • Thomas Stripling (Giants): Back, D15
  • Michael Conforto (Giants): Hamstring, D10
  • Michael Kelly (Guardians): Back, D15
  • Shane Bieber (Guardians): Elbow, D60
  • Triston McKenzie (Guardians): Elbow, D60

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.