Guardians vs Mariners Prediction, Odds & Player Prop Bets Today – MLB, Mar 27

Seattle Mariners left fielder Randy Arozarena throws to the infield during the third inning of a spring training baseball game against the Colorado Rockies Sunday, March 2, 2025, in Scottsdale, Ariz.
(AP Photo/Ross D. Franklin)
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  • The Mariners are -175 favorites vs the Guardians
  • Guardians vs Mariners Over / Under today: 7 Runs
  • Guardians / Mariners TV Channel: ATV

The Cleveland Guardians (+145) visit T-Mobile Park to take on the Seattle Mariners (-175) on March 27, 2026. First pitch is scheduled for 9:45 pm in Seattle, WA.

This season, the Guardians are 1-0 against the spread (ATS), while the Mariners are 0-1 ATS.

Guardians vs Mariners Starting Pitchers Today:

  • Guardians starting pitcher: Gavin Williams 0-0, 0.00 ERA
  • Mariners starting pitcher: George Kirby 0-0, 0.00 ERA

Guardians vs. Mariners Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians+1.5 -170O 7 -115+145
Mariners -1.5 +140U 7 -105-175

Guardians vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Friday‘s MLB game with 57.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Brayan Rocchio has hit the Home Runs Over in 2 of his last 5 games (+20.00 Units / 400% ROI)
  • Gavin Williams has hit the Hits Allowed Under in 20 of his last 25 games (+14.00 Units / 47% ROI)
  • Steven Kwan has hit the Hits Under in 7 of his last 9 games (+8.05 Units / 60% ROI)
  • Steven Kwan has hit the Singles Under in 7 of his last 8 games (+7.05 Units / 87% ROI)
  • Gavin Williams has hit the Walks Allowed Over in 11 of his last 15 away games (+7.00 Units / 36% ROI)

And here are some favorite MLB player prop bets for Mariners players for Friday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

  • Josh Naylor has hit the Home Runs Over in 3 of his last 7 games (+13.60 Units / 194% ROI)
  • Josh Naylor has hit the Singles Over in 18 of his last 25 games (+11.50 Units / 42% ROI)
  • Josh Naylor has hit the Hits Runs and RBIs Over in 18 of his last 25 games (+10.65 Units / 37% ROI)
  • Josh Naylor has hit the Total Bases Over in 17 of his last 25 games (+10.55 Units / 32% ROI)
  • Cal Raleigh has hit the RBIs Under in 16 of his last 20 games at home (+9.00 Units / 25% ROI)
  • The Cleveland Guardians have hit the Moneyline in 49 of their last 77 games (+21.25 Units / 23% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 39 of their last 60 away games (+18.30 Units / 28% ROI)
  • The Cleveland Guardians have covered the Run Line in 38 of their last 57 away games (+17.05 Units / 21% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 33 of their last 50 away games (+14.05 Units / 23% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 90 of their last 162 games (+9.19 Units / 5% ROI)
  • The Seattle Mariners have hit the Game Total Over in 92 of their last 162 games (+19.65 Units / 11% ROI)
  • The Seattle Mariners have hit the Moneyline in 38 of their last 54 games at home (+16.75 Units / 19% ROI)
  • The Seattle Mariners have covered the 1st Five Innings (F5) Run Line in 28 of their last 44 games (+9.65 Units / 18% ROI)
  • The Seattle Mariners have covered the Run Line in 21 of their last 33 games (+9.30 Units / 22% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Moneyline in 25 of their last 44 games (+7.65 Units / 11% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 1-0 against the Run Line (+1 Units / 68.97% ROI).

  • 1-0 when betting on the Moneyline for +1.55 Units / 155% ROI
  • 1-0 when betting on the total runs Over for +1 Units / 86.96% ROI
  • 0-1 when betting on the total runs Under for -1.05 Units / -100% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 0-1 against the Run Line (-1 Units / -100% ROI).

  • 0-1 when betting on the Moneyline for -1.8 Units / -100% ROI
  • 1-0 when betting on the total runs Over for +1 Units / 86.96% ROI
  • 0-1 when betting on the total runs Under for -1.05 Units / -100% ROI

Mariners vs Guardians Home Run Prop Bets Today

Yes
Cal Raleigh (SEA) +310
Julio Rodriguez (SEA) +425
Josh Naylor (SEA) +450
Jose Ramirez (CLE) +550
Chase DeLauter (CLE) +600

Mariners vs Guardians Total Hits Prop Bets Today

Over Under
Julio Rodriguez (SEA) 0.5 -220 0.5 +165
Steven Kwan (CLE) 0.5 -210 0.5 +160
Brendan Donovan (SEA) 0.5 -200 0.5 +155
Josh Naylor (SEA) 0.5 -185 0.5 +135
Jose Ramirez (CLE) 0.5 -165 0.5 +125

Mariners vs Guardians RBI Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +145 0.5 -190
Julio Rodriguez (SEA) 0.5 +170 0.5 -225
Josh Naylor (SEA) 0.5 +175 0.5 -235
Kyle Manzardo (CLE) 0.5 +220 0.5 -300
Jose Ramirez (CLE) 0.5 +230 0.5 -325

Mariners vs Guardians Strikeout Prop Bets Today

Over Under
Gavin Williams (CLE) 5.5 -135 5.5 +105
George Kirby (SEA) 5.5 -130 5.5 +100

Guardians Keys to the Game vs. the Mariners

The Guardians were 24-2 (.923) when they had 5 or more XBH in the 2025 season — 2nd best in MLB; League Avg: .799.

The Guardians were 50-8 (.847) when they scored 5 or more runs in the 2025 season — tied for 4th best in MLB; League Avg: .797.

The Guardians were 66-5 (.930) when leading entering the 7th inning in the 2025 season — 2nd best in MLB; League Avg: .875.

The Guardians were 69-4 (.945) when leading entering the 8th inning in the 2025 season — 4th best in MLB; League Avg: .909.

Mariners Keys to the Game vs. the Guardians

The Mariners were just 10-26 (.278) vs top 10 scoring offenses in the 2025 season Today, they face the Guardians (second in runs scored).

The Mariners were 70-3 (.959) when leading entering the 8th inning in the 2025 season — best in MLB; League Avg: .909.

The Mariners were 5-59 (.078) when trailing entering the 9th inning in the 2025 season — 5th best in MLB; League Avg: .043.

The Mariners were 9-55 (.141) when trailing entering the 8th inning in the 2025 season — 3rd best in MLB; League Avg: .090.

The Guardians batted just .186 in righty-righty matchups in the 2025 season — lowest in MLB.

Guardians hitters had an OPS of just .545 (690 PA’s) in righty-righty matchups in the 2025 season — lowest in MLB.

The Guardians batted just .226 in the 2025 season — 2nd lowest in MLB.

Guardians hitters slugged just .295 in righty-righty matchups in the 2025 season — lowest in MLB.

Mariners hitters slugged .712 on the first pitch of at-bats in the 2025 season — best in MLB.

The Mariners are batting just .227 when facing the starting pitcher for the 3rd time in a game since the 2024 season — lowest in MLB.

The Mariners were just 10-26 (.278) against the run line (-46.6% ROI) vs top 10 scoring offenses in the 2025 season Today, they face the Guardians (second in runs scored).

Mariners hitters slugged .444 on the road in the 2025 season — 2nd best in MLB.

Opponents had a chase percentage of just 26% against the Guardians pitchers in the 2025 season — lowest in MLB.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

The Guardians allowed 3.91 runs per game (317/81) on the road in the 2025 season — 2nd best in MLB.

Guardians pitchers allowed opponents to score in three different innings in 37% of their games in the 2025 season — lowest in MLB.

Mariners pitchers walked 7% of batters in the 2025 season — 3rd best in MLB.

The Mariners pitchers have allowed division opponents to score first in just 30% of their games since the 2024 season — lowest in MLB.

The Mariners pitchers have allowed division opponents to score first in just 33% of their games since the 2023 season — lowest in MLB.

Mariners pitchers have allowed an OBP of just .267 (2,910 PA’s) when facing the leadoff batter in the inning since the 2024 season — best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.