• The Guardians are -118 favorites vs the Orioles
• Guardians vs Orioles Over / Under today: 8.5 Runs
• Guardians / Orioles TV Channel: GDTV | MASN

The Cleveland Guardians (-118) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-102) on September 9, 2026. First pitch is scheduled for 6:35 pm in Baltimore, MD.

This season, the Guardians are against the spread (ATS), while the Orioles are ATS.

Guardians vs Orioles Starting Pitchers Today:

• Guardians starting pitcher: Foster Griffin 15-4, 3.26 ERA
• Orioles starting pitcher: Shane Baz 5-15, 3.88 ERA

Guardians vs. Orioles Odds, Run Line, Over/Under & Moneyline

Guardians vs Orioles Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Wednesday‘s MLB game with 53.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Guardians vs Orioles and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Brayan Rocchio has hit the Home Runs Over in 2 of his last 6 games (+16.00 Units / 267% ROI)
• Steven Kwan has hit the Hits Over in 16 of his last 20 away games (+11.00 Units / 28% ROI)
• Jose Ramirez has hit the RBIs Under in 17 of his last 20 games (+10.85 Units / 27% ROI)
• Travis Bazzana has hit the Runs Under in 19 of his last 25 games (+9.95 Units / 22% ROI)
• Angel Martinez has hit the Total Bases Over in 16 of his last 25 games (+9.00 Units / 29% ROI)

And here are some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Best Bets Today:

• Dylan Beavers has hit the Home Runs Over in 3 of his last 8 games at home (+14.70 Units / 184% ROI)
• Gunnar Henderson has hit the Runs Under in 17 of his last 20 games at home (+12.20 Units / 37% ROI)
• Gunnar Henderson has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+12.15 Units / 39% ROI)
• Jackson Holliday has hit the Hits Under in 16 of his last 25 games at home (+11.75 Units / 47% ROI)
• Samuel Basallo has hit the Singles Under in 19 of his last 25 games (+10.95 Units / 30% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Game Total Under in 31 of their last 50 away games (+9.70 Units / 17% ROI)
• The Cleveland Guardians have hit the Moneyline in 29 of their last 50 away games (+9.65 Units / 17% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 30 away games (+3.35 Units / 10% ROI)
• The Cleveland Guardians have covered the Run Line in 29 of their last 50 away games (+3.35 Units / 5% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 22 of their last 50 away games (+3.15 Units / 5% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 28 of their last 40 games at home (+14.60 Units / 30% ROI)
• The Baltimore Orioles have hit the Team Total Under in 24 of their last 35 games at home (+11.85 Units / 29% ROI)
• The Baltimore Orioles have hit the Game Total Under in 17 of their last 25 games at home (+9.60 Units / 35% ROI)
• The Baltimore Orioles have covered the Run Line in 26 of their last 50 games at home (+3.65 Units / 6% ROI)
• The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 15 of their last 25 games (+3.10 Units / 10% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Guardians Keys to the Game vs. the Orioles

The Guardians are 190-12 (.941) when leading entering the 7th inning since the 2024 season — best in MLB.

The Guardians were 82-0 (1.000) when leading entering the 9th inning in the 2024 season — best in MLB; League Avg: .949.

The Guardians were 71-2 (.973) when leading entering the 7th inning in the 2024 season — best in MLB; League Avg: .856.

The Guardians were 33-4 (.868) when they had 10 or more hits in the 2025 season — 2nd best in MLB; League Avg: .743.

Orioles Keys to the Game vs. the Guardians

The Orioles are just 8-28 (.222) when allowing 2 or more home runs this season — tied for 5th lowest in MLB.

The Orioles are just 3-6 (.333) when tied entering the 8th inning this season — tied for 4th lowest in MLB.

The Orioles were just 1-77 (.013) when trailing entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .043.

The Orioles are just 13-21 (.382) when tied entering the 8th inning since the 2024 season — 3rd lowest in MLB.

Guardians Hitting Stats & Trends

Guardians hitters are slugging just .346 against LHP this season — 2nd lowest in MLB.

Guardians hitters have an OPS of just .660 (1,677 PA’s) against LHP this season — 3rd lowest in MLB.

Guardians hitters have an OPS of just .649 (1,714 PA’s) in innings 7-9 this season — lowest in MLB.

Guardians hitters have an OPS of just .686 (5,500 PA’s) this season — 3rd lowest in MLB.

Orioles Hitting Stats & Trends

Orioles hitters are slugging just .483 on the first pitch of at-bats this season — 2nd lowest in MLB.

Orioles hitters have an OPS of .766 (1,348 PA’s) on pitches 95 mph or greater this season — best in MLB.

Orioles hitters are slugging just .191 on pitches out of the zone this season — tied for 3rd lowest in MLB.

Orioles hitters have struck out in 26% of their PA’s against LHP this season — highest in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 30% in close and late situations this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 4th best in MLB.

Guardians pitchers have a strikeout rate of 28% in late innings this season — best in MLB.

Opponents have a miss rate of 28% against Guardians pitchers this season — tied for 3rd best in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers have allowed a run 36% of the time after their offense scores this season — 2nd highest in MLB.

Orioles pitchers has induced two-strike counts to 51% of batters they faced (2,817/5,582 PA’s) this season — 4th lowest in MLB.

Orioles pitchers are throwing just 3.82 pitches per plate appearance this season — 5th lowest in MLB.

Orioles pitchers have walked 5% of batters when facing the leadoff batter in the inning over the last 14 days — tied for 2nd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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