• The Guardians are -130 favorites vs the Royals
• Guardians vs Royals Over / Under today: 8.5 Runs
• Guardians / Royals TV Channel: GDTV | RYTV

The Cleveland Guardians (-130) visit Kauffman Stadium to take on the Kansas City Royals (+105) on September 26, 2026. First pitch is scheduled for 7:10 pm in Kansas City, MO.

This season, the Guardians are 84-76 against the spread (ATS), while the Royals are 74-80 ATS.

Guardians vs Royals Starting Pitchers Today:

• Guardians starting pitcher: Tanner Bibee 6-15, 4.39 ERA
• Royals starting pitcher: Michael Wacha 9-9, 3.37 ERA

Guardians vs. Royals Odds, Run Line, Over/Under & Moneyline

Guardians vs Royals Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Saturday‘s MLB game with 54.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Guardians players for Saturday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Angel Martinez has hit the Home Runs Over in 3 of his last 9 games (+17.10 Units / 190% ROI)
• Angel Martinez has hit the Hits Over in 14 of his last 15 away games (+12.85 Units / 46% ROI)
• Angel Martinez has hit the Total Bases Over in 12 of his last 15 away games (+11.75 Units / 63% ROI)
• Steven Kwan has hit the Hits Runs and RBIs Over in 15 of his last 20 away games (+9.70 Units / 41% ROI)
• Steven Kwan has hit the Singles Over in 19 of his last 25 away games (+9.25 Units / 23% ROI)

And here are some favorite MLB player prop bets for Royals players for Saturday‘s game, looking at profitable historical betting trends:

Best Royals Player Prop Best Bets Today:

• Vinnie Pasquantino has hit the Home Runs Over in 3 of his last 8 games (+14.90 Units / 186% ROI)
• Salvador Perez has hit the Runs Under in 21 of his last 25 games (+12.95 Units / 27% ROI)
• Carter Jensen has hit the Total Bases Over in 18 of his last 25 games (+12.50 Units / 41% ROI)
• Salvador Perez has hit the Hits Over in 21 of his last 25 games at home (+12.25 Units / 23% ROI)
• Carter Jensen has hit the Hits Runs and RBIs Over in 18 of his last 25 games (+10.40 Units / 37% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Moneyline in 24 of their last 35 games (+9.25 Units / 18% ROI)
• The Cleveland Guardians have hit the Game Total Under in 30 of their last 50 away games (+7.75 Units / 14% ROI)
• The Cleveland Guardians have covered the Run Line in 7 of their last 8 games (+6.75 Units / 60% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 8 of their last 11 games (+6.50 Units / 39% ROI)
• The Cleveland Guardians have hit the Team Total Over in 11 of their last 16 games (+5.30 Units / 28% ROI)

Royals Best Bets Today:

• The Kansas City Royals have hit the 1st Five Innings (F5) Team Total Over in 27 of their last 45 games at home (+8.00 Units / 15% ROI)
• The Kansas City Royals have hit the Moneyline in 21 of their last 35 games at home (+7.50 Units / 19% ROI)
• The Kansas City Royals have hit the Game Total Under in 12 of their last 18 games (+5.50 Units / 28% ROI)
• The Kansas City Royals have covered the Run Line in 19 of their last 35 games at home (+3.35 Units / 7% ROI)
• The Kansas City Royals have hit the Team Total Over in 14 of their last 23 games at home (+3.15 Units / 11% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 76-83 against the Run Line (-12.1 Units / -5.93% ROI).

• 84-76 when betting on the Moneyline for -1.35 Units / -0.67% ROI
• 76-82 when betting on the total runs Over for -13.1 Units / -7.53% ROI
• 82-76 when betting on the total runs Under for -2.6 Units / -1.46% ROI

Royals Against the Spread (ATS) Record

Against the spread this season, the Royals are 74-80 against the Run Line (-26.95 Units / -12.2% ROI).

• 68-92 when betting on the Moneyline for -22.9 Units / -12.94% ROI
• 72-83 when betting on the total runs Over for -18.75 Units / -10.64% ROI
• 83-72 when betting on the total runs Under for +4.55 Units / 2.59% ROI

Guardians Keys to the Game vs. the Royals

The Guardians are 19-20 (.487) when their opponents score in the first inning this season — 3rd best in MLB.

The Guardians are 61-5 (.924) when leading entering the 7th inning this season — 5th best in MLB.

The Guardians were 71-2 (.973) when leading entering the 7th inning in the 2024 season — best in MLB; League Avg: .856.

The Guardians are 198-12 (.943) when leading entering the 7th inning since the 2024 season — best in MLB.

Royals Keys to the Game vs. the Guardians

The Royals are just 33-17 (.660) when they’ve had 10 or more hits this season — 3rd lowest in MLB.

The Royals are just 55-13 (.809) when leading entering the 8th inning this season — 2nd lowest in MLB.

The Royals are just 9-51 (.150) when allowing 10 or more hits this season — 3rd lowest in MLB.

The Royals are just 8-38 (.174) when allowing 2 or more home runs this season — 2nd lowest in MLB.

Guardians Hitting Stats & Trends

Guardians hitters are slugging just .357 against LHP this season — 2nd lowest in MLB.

The Guardians are batting just .229 against LHP this season — tied for 2nd lowest in MLB.

Guardians hitters have an OPS of just .671 (1,919 PA’s) against LHP this season — 4th lowest in MLB.

Guardians hitters have an OPS of just .644 (1,879 PA’s) in innings 7-9 this season — lowest in MLB.

Royals Hitting Stats & Trends

Royals hitters are slugging just .366 on the road this season — 3rd lowest in MLB.

Royals hitters are slugging .438 at home this season — 5th best in MLB.

Royals hitters have put 40% of their swings in play on the first pitch of at-bats this season — highest in MLB.

Royals hitters have an OPS of just .665 (3,064 PA’s) on the road this season — 3rd lowest in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 31% in close and late situations this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 4th best in MLB.

Guardians pitchers have a strikeout rate of 26% with runners in scoring position this season — best in MLB.

Guardians pitchers have a strikeout rate of 28% in late innings this season — best in MLB.

Royals Pitching Stats & Trends

Royals pitchers have a strikeout rate of just 38% with two-strikes this season — 2nd lowest in MLB.

Royals pitchers have a strikeout rate of just 19% this season — 3rd lowest in MLB.

Royals pitchers have allowed a run 37% of the time after their offense scores this season — 2nd highest in MLB.

Royals pitchers have a strikeout rate of just 19% in late innings this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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