• The Tigers are -150 favorites vs the Guardians
• Guardians vs Tigers Over / Under today: 8 Runs
• Guardians / Tigers TV Channel: FS1 | DSN | GDTV

The Cleveland Guardians (+125) visit Comerica Park to take on the Detroit Tigers (-150) on May 18, 2026. First pitch is scheduled for 6:40 pm in Detroit, MI.

This season, the Guardians are 26-22 against the spread (ATS), while the Tigers are 19-25 ATS.

Guardians vs Tigers Starting Pitchers Today:

• Guardians starting pitcher: Slade Cecconi 2-4, 5.61 ERA
• Tigers starting pitcher: Framber Valdez 2-2, 4.30 ERA

Guardians vs. Tigers Odds, Run Line, Over/Under & Moneyline

Guardians vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Monday‘s MLB game with 55.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Guardians vs Tigers and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Guardians players for Monday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Angel Martinez has hit the Home Runs Over in 4 of his last 5 games (+27.90 Units / 558% ROI)
• Steven Kwan has hit the Walks Over in 10 of his last 15 games (+12.00 Units / 80% ROI)
• Rhys Hoskins has hit the Runs Over in 15 of his last 25 games (+12.00 Units / 48% ROI)
• Patrick Bailey has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+11.35 Units / 47% ROI)
• Jose Ramirez has hit the RBIs Under in 20 of his last 25 games (+10.90 Units / 23% ROI)

And here are some favorite MLB player prop bets for Tigers players for Monday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

• Zach McKinstry has hit the Runs Under in 22 of his last 25 games (+15.60 Units / 27% ROI)
• Riley Greene has hit the Total Bases Over in 18 of his last 25 games (+15.25 Units / 54% ROI)
• Matt Vierling has hit the Home Runs Over in 2 of his last 5 games at home (+14.50 Units / 290% ROI)
• Wenceel Perez has hit the Hits Under in 14 of his last 20 games at home (+13.15 Units / 66% ROI)
• Riley Greene has hit the Singles Over in 17 of his last 25 games (+11.00 Units / 44% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 34 of their last 50 away games (+16.15 Units / 27% ROI)
• The Cleveland Guardians have hit the Moneyline in 21 of their last 35 away games (+12.00 Units / 32% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 19 of their last 35 away games (+11.25 Units / 30% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 8 of their last 10 away games (+6.10 Units / 51% ROI)
• The Cleveland Guardians have hit the Team Total Over in 8 of their last 10 games (+5.80 Units / 48% ROI)

Tigers Best Bets Today:

• The Detroit Tigers have hit the Team Total Over in 30 of their last 50 games at home (+8.05 Units / 14% ROI)
• The Detroit Tigers have hit the Game Total Over in 28 of their last 50 games at home (+7.15 Units / 13% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 28 of their last 50 games at home (+4.80 Units / 8% ROI)
• The Detroit Tigers have covered the Run Line in 11 of their last 22 games at home (+4.75 Units / 18% ROI)
• The Detroit Tigers have hit the Moneyline in 14 of their last 22 games at home (+4.75 Units / 16% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 25-23 against the Run Line (+3.2 Units / 5.42% ROI).

• 26-22 when betting on the Moneyline for +3.5 Units / 6.04% ROI
• 25-23 when betting on the total runs Over for -0.1 Units / -0.19% ROI
• 23-25 when betting on the total runs Under for -4.6 Units / -8.67% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 19-25 against the Run Line (-8.25 Units / -13.6% ROI).

• 20-27 when betting on the Moneyline for -10.65 Units / -18.54% ROI
• 21-24 when betting on the total runs Over for -5.45 Units / -10.5% ROI
• 24-21 when betting on the total runs Under for +1.05 Units / 2.04% ROI

Tigers vs Guardians Home Run Prop Bets Today

Tigers vs Guardians Total Hits Prop Bets Today

Tigers vs Guardians Strikeout Prop Bets Today

Guardians Keys to the Game vs. the Tigers

The Guardians are 10-1 (.909) when they’ve had 10 or more hits this season — 5th best in MLB; League Avg: .756.

The Guardians are just 0-20 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .051.

The Guardians are 19-1 (.950) when leading entering the 7th inning this season — 4th best in MLB; League Avg: .866.

The Guardians are 85-6 (.934) when leading entering the 7th inning since the 2025 season — tied for best in MLB; League Avg: .873.

Tigers Keys to the Game vs. the Guardians

The Tigers are just 1-9 (.100) when their opponents score in the first inning this season — lowest in MLB; League Avg: .362.

The Tigers are just 14-7 (.667) when leading entering the 7th inning this season — lowest in MLB; League Avg: .866.

The Tigers are just 13-3 (.812) when leading entering the 8th inning this season — 2nd lowest in MLB; League Avg: .895.

The Tigers are just 9-17 (.346) after a loss this season — tied for 3rd lowest in MLB; League Avg: .480.

Guardians Hitting Stats & Trends

Guardians hitters have drawn walks in 12% of their PA’s against RHP this season — 2nd best in MLB.

8% of Guardians’ hitters plate appearances have lasted only one pitch (150/1,815 PA’s) this season — lowest in MLB.

Guardians hitters have chased 22% of pitches out of the zone in righty-righty matchups this season — lowest in MLB.

Guardians hitters have a swing rate of just 42% in righty-righty matchups this season — lowest in MLB.

Tigers Hitting Stats & Trends

The Tigers are batting just .217 against LHP this season — 5th lowest in MLB.

Tigers hitters have chased 24% of pitches out of the zone against LHP this season — lowest in MLB.

The Tigers are batting .261 with two outs this season — 2nd best in MLB.

Tigers hitters have drawn walks in 13% of their PA’s against LHP this season — best in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 35% in close and late situations this season — best in MLB.

Guardians pitchers have struck out 28% of left-handed batters they faced this season — best in MLB.

Opponents have a miss rate of 29% against Guardians pitchers this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — tied for 4th best in MLB.

Tigers Pitching Stats & Trends

Tigers pitchers have walked 7% of batters when facing the leadoff batter in the inning this season — 5th best in MLB.

Tigers pitchers have a first-pitch strike rate of 63% this season — 4th highest in MLB.

Tigers pitchers have induced opposing hitters to ground into 37 double plays in 341 opportunities (11%) this season — 5th best in MLB.

Tigers pitchers have allowed 12 home runs at home this season — fewest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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