• The Guardians are -125 favorites vs the White Sox
• Guardians vs White Sox Over / Under today: 7.5 Runs
• Guardians / White Sox TV Channel: FOX

The Cleveland Guardians (-125) visit Rate Field to take on the Chicago White Sox (+105) on August 8, 2026. First pitch is scheduled for 7:15 pm in Chicago, IL.

This season, the Guardians are 58-59 against the spread (ATS), while the White Sox are 65-47 ATS.

Guardians vs White Sox Starting Pitchers Today:

• Guardians starting pitcher: Gavin Williams 11-6, 3.56 ERA
• White Sox starting pitcher: Anthony Kay 8-5, 4.00 ERA

Guardians vs. White Sox Odds, Run Line, Over/Under & Moneyline

Guardians vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Saturday‘s MLB game with 52.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Guardians vs White Sox and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Guardians players for Saturday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Patrick Bailey has hit the Home Runs Over in 3 of his last 9 games (+18.00 Units / 200% ROI)
• Jose Ramirez has hit the RBIs Under in 18 of his last 20 games (+13.80 Units / 32% ROI)
• Steven Kwan has hit the Hits Over in 18 of his last 20 games (+13.60 Units / 32% ROI)
• Gavin Williams has hit the Walks Allowed Under in 15 of his last 20 games (+11.40 Units / 48% ROI)
• Jose Ramirez has hit the Walks Under in 13 of his last 15 away games (+9.05 Units / 30% ROI)

And here are some favorite MLB player prop bets for White Sox players for Saturday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

• Chase Meidroth has hit the Home Runs Over in 2 of his last 6 games at home (+18.00 Units / 300% ROI)
• Drew Romo has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+14.35 Units / 49% ROI)
• Munetaka Murakami has hit the Total Bases Over in 16 of his last 20 games at home (+13.10 Units / 53% ROI)
• Drew Romo has hit the Hits Under in 18 of his last 25 games (+10.95 Units / 40% ROI)
• Chase Meidroth has hit the Singles Under in his last 9 games at home (+9.20 Units / 90% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Game Total Under in 26 of their last 40 away games (+10.25 Units / 23% ROI)
• The Cleveland Guardians have hit the Team Total Under in 24 of their last 40 away games (+6.10 Units / 13% ROI)
• The Cleveland Guardians have covered the Run Line in 9 of their last 12 away games (+5.55 Units / 32% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 21 of their last 50 away games (+5.30 Units / 9% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in their last 5 games (+5.25 Units / 85% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have hit the Moneyline in 30 of their last 45 games at home (+15.95 Units / 31% ROI)
• The Chicago White Sox have covered the Run Line in 29 of their last 45 games at home (+11.70 Units / 19% ROI)
• The Chicago White Sox have hit the Game Total Over in 23 of their last 40 games at home (+5.35 Units / 12% ROI)
• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 22 games at home (+5.30 Units / 21% ROI)
• The Chicago White Sox have hit the Team Total Under in 12 of their last 19 games at home (+3.90 Units / 17% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 56-60 against the Run Line (-7.4 Units / -4.9% ROI).

• 58-59 when betting on the Moneyline for -5.6 Units / -3.98% ROI
• 56-61 when betting on the total runs Over for -10.6 Units / -8.3% ROI
• 61-56 when betting on the total runs Under for -1.3 Units / -1% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 65-47 against the Run Line (+4.25 Units / 2.59% ROI).

• 59-56 when betting on the Moneyline for +10.35 Units / 8.41% ROI
• 65-48 when betting on the total runs Over for +12.5 Units / 9.93% ROI
• 48-65 when betting on the total runs Under for -23.85 Units / -18.76% ROI

White Sox vs Guardians Home Run Prop Bets Today

White Sox vs Guardians Total Hits Prop Bets Today

White Sox vs Guardians Strikeout Prop Bets Today

Guardians Keys to the Game vs. the White Sox

The Guardians were 77-2 (.975) when leading entering the 8th inning in the 2024 season — best in MLB; League Avg: .899.

The Guardians were 33-4 (.868) when they had 10 or more hits in the 2025 season — 2nd best in MLB; League Avg: .743.

The Guardians were 12-6 (.667) when tied entering the 8th inning in the 2025 season — tied for 3rd best in MLB; League Avg: .500.

The Guardians were 71-2 (.973) when leading entering the 7th inning in the 2024 season — best in MLB; League Avg: .856.

White Sox Keys to the Game vs. the Guardians

The White Sox were just 40-103 (.280) when allowing 5 or more extra base hits in the 2024 season — lowest in MLB; League Avg: .538.

The White Sox were just 41-121 (.253) in the 2024 season — lowest in MLB; League Avg: .500.

The White Sox were just 0-79 (.000) when trailing entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .143.

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

Guardians Hitting Stats & Trends

The Guardians are batting just .217 on the road this season — lowest in MLB.

Guardians hitters are slugging just .369 this season — lowest in MLB.

Guardians hitters have an OPS of just .691 (3,070 PA’s) against RHP this season — 4th lowest in MLB.

Guardians hitters are slugging just .360 on the road this season — 2nd lowest in MLB.

White Sox Hitting Stats & Trends

White Sox hitters have 56 extra-base hits out of 116 total hits (48%) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

30% of White Sox hitters strikeouts have come on 95+ MPH fastballs this season — tied for 2nd highest in MLB.

White Sox hitters have an OBP of just .236 (2,296 PA’s) with two-strikes this season — 4th lowest in MLB.

White Sox hitters have grounded into 51 double plays in 814 opportunities (6%) this season — best in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 25% this season — 3rd best in MLB.

Opponents have a miss rate of 27% against Guardians pitchers this season — 4th best in MLB.

Guardians pitchers have a strikeout rate of 27% in late innings this season — tied for best in MLB.

Guardians pitchers have a strikeout rate of 25% with runners in scoring position this season — 2nd best in MLB.

White Sox Pitching Stats & Trends

The White Sox have won 52% of home games in which their opponents scored first this season — 2nd highest in MLB.

The White Sox pitchers have allowed their opponents to score first in just 37% of their games on the road this season — 3rd lowest in MLB.

White Sox pitchers have an ERA of 3.38 (519.0 IP) at home this season — 4th best in MLB.

White Sox pitchers have an ERA of 3.13 (276.1 IP) against division opponents this season — 4th best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Guardians vs White Sox and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.