- The White Sox (46-46) are -155 favorites vs the Guardians (46-44)
- Guardians starting pitcher: Cal Quantrill (6-5), 3.75 ERA
- White Sox starting pitcher: Lucas Giolito (6-5), 4.68 ERA
- Watch the game on Apple TV+
The Cleveland Guardians (+125) visit Guaranteed Rate Field to take on the Chicago White Sox (-155) on Friday, July 22, 2022. First pitch is scheduled for 8:10pm EDT in Chicago.
The White Sox are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+125).
The Guardians vs White Sox Over/Under is 8.5 total runs for the game.
So far this season, the Guardians are 46-44 against the spread (ATS), while the White Sox are 43-49 ATS.
Guardians vs. White Sox Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Guardians | +1.5 -155 | O 8.5 -115 | +125 |
| White Sox | -1.5 +125 | U 8.5 -105 | -155 |
Guardians vs White Sox Prediction for Today’s Game
Based on recent trends the model predicts the White Sox will win Friday‘s matchup with 58.0% confidence.
This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Guardians and White Sox and up-to-date player injuries.
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Best Guardians Player Prop Bets Today
We’ve highlighted some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:
- Owen Miller has hit the Runs Under in 18 of his last 20 games (+13.70 Units / 32% ROI)
- Myles Straw has hit the Runs Under in 14 of his last 16 away games (+10.80 Units / 40% ROI)
- Myles Straw has hit the Hits Under in 24 of his last 43 away games (+10.80 Units / 19% ROI)
- Jose Ramirez has hit the RBIs Under in 17 of his last 21 away games (+10.75 Units / 31% ROI)
- Jose Ramirez has hit the Runs Under in 18 of his last 25 games (+9.85 Units / 31% ROI)
Best White Sox Player Prop Best Bets Today
And here are some favorite MLB player prop bets for White Sox players for Friday‘s game, looking at profitable historical betting trends:
- Jose Abreu has hit the Singles Over in 36 of his last 49 games (+23.60 Units / 45% ROI)
- Jose Abreu has hit the Hits Over in 40 of his last 51 games (+22.35 Units / 20% ROI)
- Jose Abreu has hit the RBIs Under in 36 of his last 44 games at home (+20.25 Units / 23% ROI)
- Danny Mendick has hit the Runs Over in 10 of his last 11 games (+15.60 Units / 142% ROI)
- Jake Burger has hit the RBIs Over in 12 of his last 17 games at home (+15.20 Units / 89% ROI)
White Sox vs Guardians Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| AJ Pollock | 0.5 +400 | 0.5 -700 |
| Andrew Vaughn | 0.5 +475 | 0.5 -1000 |
| Gavin Sheets | 0.5 +350 | 0.5 -650 |
| Jose Abreu | 0.5 +375 | 0.5 -650 |
| Josh Harrison | 0.5 +625 | 0.5 -2000 |
White Sox vs Guardians Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| AJ Pollock | 0.5 -190 | 0.5 +135 |
| Andrew Vaughn | 0.5 -250 | 0.5 +165 |
| Gavin Sheets | 0.5 -200 | 0.5 +145 |
| Jose Abreu | 0.5 -275 | 0.5 +185 |
| Josh Harrison | 0.5 -185 | 0.5 +130 |
White Sox vs Guardians RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| AJ Pollock | 0.5 +180 | 0.5 -275 |
| Andrew Vaughn | 0.5 +175 | 0.5 -250 |
| Gavin Sheets | 0.5 +145 | 0.5 -200 |
| Jose Abreu | 0.5 +130 | 0.5 -190 |
| Josh Harrison | 0.5 +210 | 0.5 -300 |
White Sox vs Guardians Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Lucas Giolito | 5.5 +110 | 5.5 -155 |
| Cal Quantrill | 3.5 -110 | 3.5 -125 |
Positive Betting Trends for the Guardians Run Line, Moneyline, Run Totals
- The Cleveland Guardians have hit the 1st Five Innings (F5) Total Under in 32 of their last 59 games (+7.85 Units / 12% ROI)
- The Cleveland Guardians have hit the Moneyline in 39 of their last 71 games (+7.55 Units / 8% ROI)
- The Cleveland Guardians have hit the Game Total Under in 31 of their last 59 games (+7.15 Units / 11% ROI)
- The Cleveland Guardians have covered the Run Line in 39 of their last 71 games (+6.45 Units / 7% ROI)
- The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 28 of their last 50 games (+5.00 Units / 9% ROI)
Positive Betting Trends for the White Sox: Run Line, Moneyline, Run Totals
- The Chicago White Sox have hit the 1st Five Innings (F5) Total Under in 26 of their last 42 games at home (+10.85 Units / 24% ROI)
- The Chicago White Sox have hit the Game Total Over in 25 of their last 47 games (+4.60 Units / 9% ROI)
- The Chicago White Sox have hit the Moneyline in 7 of their last 10 games (+3.70 Units / 28% ROI)
- The Chicago White Sox have covered the Run Line in 6 of their last 10 games (+1.95 Units / 16% ROI)
- The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 3 of their last 5 games (+1.20 Units / 21% ROI)
Guardians Against the Spread (ATS) Record
Against the spread this MLB season, the Guardians have gone 47-43 against the Run Line (+1.3 Units / 1.16% ROI).
- 46-44 when betting on the Moneyline for +2.6 Units / 2.38% ROI
- 41-43 when betting on the total runs Over for -6.45 Units / -6.49% ROI
- 43-41 when betting on the total runs Under for -2 Units / -2.02% ROI
White Sox Against the Spread (ATS) Record
Against the spread this MLB season, the Guardians have gone 43-49 against the Run Line (-7.75 Units / -6.89% ROI).
- 46-46 when betting on the Moneyline for -8.45 Units / -7.14% ROI
- 43-44 when betting on the total runs Over for -4.15 Units / -4.13% ROI
- 44-43 when betting on the total runs Under for -2.95 Units / -2.89% ROI
Cal Quantrill: Guardians Starting Pitcher Stats & Trends
Cal Quantrill has a strikeout rate of just 30% (63 SO in 208 PAs) with two-strikes this season — 2nd lowest among qualified SPs in MLB; League Avg: 43% — third Percentile.
Right-handed hitters have a miss rate of just 16% (71/444) against Cal Quantrill this season — lowest among qualified SPs in MLB; League Avg: 26% — first Percentile.
Opponents have a miss rate of just 19% (145/769) against Cal Quantrill this season — 6th lowest among qualified SPs in MLB; League Avg: 25% — eighth Percentile.
Cal Quantrill has allowed a slugging percentage of .870 (20 Total Bases / 23 ABs) in late innings this season — 2nd highest among qualified SPs in MLB; League Avg: .400 — fourth Percentile.
Lucas Giolito: White Sox Starting Pitcher Stats & Trends
Lucas Giolito has allowed an OPS of .982 (222 PA’s) against right-handed batters this season — 2nd highest in MLB among starting pitchers with at least 45 total IP; League Avg: .707 — first Percentile.
Opponents have a miss rate of 28% (31/110) against Lucas Giolito on inside fastballs this season — best in MLB among starting pitchers with at least 45 total IP; League Avg: 15% — 100th Percentile.
Lucas Giolito has allowed a slugging percentage of .599 (118 Total Bases / 197 ABs) against right-handed batters this season — highest in MLB among starting pitchers with at least 45 total IP; League Avg: .402 — 0 Percentile.
Lucas Giolito has allowed a slugging percentage of .558 (58 Total Bases / 104 ABs) on breaking pitches this season — 3rd highest in MLB among starting pitchers with at least 45 total IP; League Avg: .364 — third Percentile.
Guardians Keys to the Game vs. the White Sox
The Guardians are 30-1 (.968) when leading entering the 8th inning this season — 3rd best in MLB; League Avg: .914.
The Guardians are 28-3 (.903) when totaling 10 or more hits this season — best in MLB; League Avg: .715.
The Guardians are 8-38 (.174) when trailing entering the 8th inning this season — 2nd best in MLB; League Avg: .086.
The Guardians are 19-8 (.704) when scoring in the first inning this season — 10th best in MLB; League Avg: .660.
White Sox Keys to the Game vs. the Guardians
The White Sox are 7-2 (.778) when tied entering the 7th inning this season — best in MLB; League Avg: .500.
The White Sox are just 4-24 (.143) when allowing 10 or more hits this season — tied for 3rd lowest in MLB; League Avg: .285.
The White Sox are 78-13 (.857) when hitting 2 or more home runs since the 2020 season — best in MLB; League Avg: .704.
The White Sox are 27-21 (.562) on the road this season — tied for 6th best in MLB; League Avg: .478.
Guardians Hitting Stats & Trends
Guardians hitters are slugging just .323 against LHP this season — lowest in MLB; League Avg: .398.
Guardians hitters have just 439 strikeouts in 2,480 PA’s (18%) against RHP this season — best in MLB; League Avg: 22%.
Guardians hitters have an OPS of just .613 (906 PA’s) against LHP this season — 2nd lowest in MLB; League Avg: .716.
Guardians hitters have missed on just 21% of swings this season — best in MLB; League Avg: 25%.
White Sox Hitting Stats & Trends
The White Sox are batting .285 against LHP this season — 2nd best in MLB; League Avg: .246.
The White Sox are batting .272 on the road this season — best in MLB; League Avg: .240.
The White Sox have won just 44% of home games in which they have scored three or more runs in an inning this season — lowest in MLB; League Avg: 78%.
The White Sox are batting just .159 in lefty-lefty matchups since the start of last season — lowest in MLB; League Avg: .227.
Guardians Pitching Stats & Trends
Guardians pitchers have walked 17 of 352 batters (5%) over the last 14 days (10 games) — 2nd best in MLB; League Avg: 8%.
Opponents have a groundball rate of 49% against Guardians pitchers this month (17 games) — tied for 2nd highest in MLB; League Avg: 43%.
Opponents have a groundball rate of 51% against Guardians pitchers over the last 14 days (10 games) — highest in MLB; League Avg: 44%.
The Guardians pitchers have allowed 200 barreled balls this season — tied for 3rd most in MLB.
White Sox Pitching Stats & Trends
White Sox pitchers have a strikeout rate of 28% in close and late situations since the start of last season — 2nd best in MLB; League Avg: 25%.
Opponents have a miss rate of 28% against White Sox pitchers since the start of last season — 3rd best in MLB; League Avg: 26%.
White Sox pitchers have walked 332 of 3,528 batters (9%) this season — tied for 3rd highest in MLB; League Avg: 8%.
White Sox pitchers have a strikeout rate of 24% with runners in scoring position since the start of last season — 4th best in MLB; League Avg: 22%.
White Sox vs. Guardians Injuries Tonight That May Affect Prop Bets
- Yasmani Grandal (White Sox): Back, D10
- Kyle Crick (White Sox): Elbow, D15
- Jonathan Stiever (White Sox): Lat, D60
- Vincent Velasquez (White Sox): Finger, D15
- Eloy Jiménez (White Sox): Leg, Day-to-Day
- Garrett Crochet (White Sox): Elbow, D60
- Aaron Bummer (White Sox): Lat, D15
- Jacob Burger (White Sox): Hand, D10
- Daniel Mendick (White Sox): Knee, D60
- Luis Robert (White Sox): Illness, Day-to-Day
- Oscar Gonzalez (Guardians): Ribs, D10
- Cody Morris (Guardians): Shoulder, D60
- Aaron Civale (Guardians): Wrist, D15
- Anthony Gose (Guardians): Triceps, D15
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