• The Mariners are -140 favorites vs the Cardinals
• Mariners vs Cardinals Over / Under today: 8.5 Runs
• Mariners / Cardinals TV Channel: MRTV | CATV

The Seattle Mariners (-140) visit Busch Stadium to take on the St. Louis Cardinals (+115) on April 26, 2026. First pitch is scheduled for 2:15 pm in St. Louis, MO.

This season, the Mariners are 13-15 against the spread (ATS), while the Cardinals are 14-11 ATS.

Mariners vs Cardinals Starting Pitchers Today:

• Mariners starting pitcher: Emerson Hancock 2-1, 2.90 ERA
• Cardinals starting pitcher: Michael McGreevy 1-2, 3.38 ERA

Mariners vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Mariners vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Sunday‘s MLB game with 58.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Mariners vs Cardinals and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Mariners players for Sunday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Bets Today:

• Cole Young has hit the Singles Over in 16 of his last 25 games (+13.75 Units / 55% ROI)
• Josh Naylor has hit the Runs Under in 20 of his last 25 games (+11.75 Units / 27% ROI)
• Cole Young has hit the Home Runs Over in 2 of his last 9 away games (+9.90 Units / 110% ROI)
• Josh Naylor has hit the Hits Under in 14 of his last 25 games (+9.75 Units / 35% ROI)
• Cole Young has hit the Hits Runs and RBIs Over in 18 of his last 25 games (+9.75 Units / 29% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• Ivan Herrera has hit the Home Runs Over in 4 of his last 10 games (+19.40 Units / 194% ROI)
• Jordan Walker has hit the Runs Over in 16 of his last 25 games (+14.15 Units / 56% ROI)
• Masyn Winn has hit the Hits Runs and RBIs Over in his last 9 games (+10.05 Units / 112% ROI)
• Masyn Winn has hit the Hits Over in his last 10 games (+10.00 Units / 54% ROI)
• Nolan Gorman has hit the Singles Over in 13 of his last 25 games (+9.85 Units / 39% ROI)

Mariners Best Bets Today:

• The Seattle Mariners have hit the Team Total Under in 29 of their last 45 away games (+10.05 Units / 19% ROI)
• The Seattle Mariners have hit the Game Total Under in 9 of their last 12 away games (+5.80 Units / 44% ROI)
• The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Under in 26 of their last 45 away games (+5.40 Units / 10% ROI)
• The Seattle Mariners have covered the Run Line in 13 of their last 25 away games (+2.25 Units / 8% ROI)
• The Seattle Mariners have hit the Moneyline in 5 of their last 7 games (+2.00 Units / 19% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 27 of their last 45 games at home (+9.50 Units / 18% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 27 of their last 45 games at home (+6.75 Units / 13% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 25 of their last 45 games at home (+4.00 Units / 8% ROI)
• The St. Louis Cardinals have hit the Moneyline in 14 of their last 25 games at home (+3.95 Units / 15% ROI)
• The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 11 of their last 17 games at home (+3.55 Units / 16% ROI)

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 10-18 against the Run Line (-6.3 Units / -20.9% ROI).

• 13-15 when betting on the Moneyline for -7.25 Units / -18.08% ROI
• 13-15 when betting on the total runs Over for -3.4 Units / -11.04% ROI
• 15-13 when betting on the total runs Under for +0.8 Units / 2.59% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 14-11 against the Run Line (-1.85 Units / -4.83% ROI).

• 14-12 when betting on the Moneyline for +3.6 Units / 13.53% ROI
• 14-11 when betting on the total runs Over for +1.85 Units / 6.49% ROI
• 11-14 when betting on the total runs Under for -4.65 Units / -16.15% ROI

Cardinals vs Mariners Home Run Prop Bets Today

Cardinals vs Mariners Total Hits Prop Bets Today

Cardinals vs Mariners Strikeout Prop Bets Today

Mariners Keys to the Game vs. the Cardinals

The Mariners are just 0-14 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .049.

The Mariners are just 0-11 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .137.

The Mariners are 79-4 (.952) when leading entering the 8th inning since the 2025 season — tied for best in MLB; League Avg: .907.

The Mariners are just 3-8 (.273) on the road this season — tied for 4th lowest in MLB; League Avg: .464.

Cardinals Keys to the Game vs. the Mariners

The Cardinals are 11-0 (1.000) when leading entering the 7th inning this season — tied for best in MLB; League Avg: .863.

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

The Cardinals are 29-19 (.604) when tied entering the 7th inning since the 2024 season — 5th best in MLB; League Avg: .499.

Mariners Hitting Stats & Trends

The Mariners are batting just .205 on the road this season — 2nd lowest in MLB.

Mariners hitters are slugging .682 on the first pitch of at-bats since the 2025 season — 2nd best in MLB.

Mariners hitters are slugging just .304 on the road this season — lowest in MLB.

Mariners hitters have an OPS of just .609 (421 PA’s) on the road this season — 2nd lowest in MLB.

Cardinals Hitting Stats & Trends

Cardinals hitters have 27 extra-base hits out of 114 total hits (just 24%) against starting pitchers this season — lowest in MLB.

The Cardinals are batting just .217 with two outs since the 2025 season — 2nd lowest in MLB.

The Cardinals are batting just .210 when facing the starting pitcher for the 3rd time in a game this season — tied for 5th lowest in MLB.

Cardinals hitters have an OPS of just .942 (1,347 PA’s) with the pitcher behind in the count since the 2025 season — lowest in MLB.

Mariners Pitching Stats & Trends

Mariners pitchers have walked 6% of batters this season — best in MLB.

Mariners pitchers have a first-pitch strike rate of 68% this season — highest in MLB.

Mariners pitchers have induced opposing hitters to ground into 30 double plays in 196 opportunities (15%) this season — best in MLB.

Mariners pitchers have thrown at least two strikes in their first three pitches to 70% of opposing batters this season — highest in MLB.

Cardinals Pitching Stats & Trends

Cardinals pitchers have a strikeout rate of just 16% this season — lowest in MLB.

Cardinals pitchers have a strikeout rate of just 33% with two-strikes this season — lowest in MLB.

Opponents have a miss rate of just 20% against Cardinals pitchers this month (21 games) — lowest in MLB.

Opponents have a miss rate of just 20% against Cardinals pitchers this season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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