• The are Not Found favorites vs the
• Nationals vs Cubs Over / Under today: Not Found Runs
• Nationals / Cubs TV Channel: MARQ | NATV

The Washington Nationals (Not Found) visit Wrigley Field to take on the Chicago Cubs (Not Found) on March 28, 2026. First pitch is scheduled for 2:20 pm in Chicago, IL.

This season, the Nationals are 1-0 against the spread (ATS), while the Cubs are 0-1 ATS.

Nationals vs Cubs Starting Pitchers Today:

• Nationals starting pitcher: Miles Mikolas 0-0, 0.00 ERA
• Cubs starting pitcher: Cade Horton 0-0, 0.00 ERA

Nationals vs. Cubs Odds, Run Line, Over/Under & Moneyline

Nationals vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Saturday‘s MLB game with 59.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Nationals vs Cubs and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Nationals players for Saturday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Bets Today:

• Jacob Young has hit the Home Runs Over in 2 of his last 3 games (+33.00 Units / 1100% ROI)
• Daylen Lile has hit the Runs Over in 16 of his last 25 games (+13.90 Units / 56% ROI)
• Daylen Lile has hit the Hits Over in 19 of his last 25 games (+13.05 Units / 28% ROI)
• Daylen Lile has hit the Total Bases Over in 17 of his last 25 games (+11.05 Units / 38% ROI)
• Daylen Lile has hit the Singles Over in 18 of his last 25 games (+9.75 Units / 32% ROI)

And here are some favorite MLB player prop bets for Cubs players for Saturday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

• Michael Busch has hit the Home Runs Over in 4 of his last 6 games (+15.00 Units / 250% ROI)
• Cade Horton has hit the Earned Runs Under in 13 of his last 15 games (+11.25 Units / 56% ROI)
• Alex Bregman has hit the Walks Over in 13 of his last 20 games (+10.25 Units / 51% ROI)
• Nico Hoerner has hit the Hits Over in 12 of his last 20 games at home (+8.55 Units / 31% ROI)
• Matt Shaw has hit the Hits Runs and RBIs Under in 8 of his last 9 games (+8.30 Units / 85% ROI)

Nationals Best Bets Today:

• The Washington Nationals have hit the Game Total Over in 48 of their last 87 games (+12.05 Units / 12% ROI)
• The Washington Nationals have hit the Moneyline in 30 of their last 66 away games (+11.40 Units / 17% ROI)
• The Washington Nationals have hit the 1st Five Innings (F5) Team Total Under in 76 of their last 136 games (+10.82 Units / 7% ROI)
• The Washington Nationals have covered the Run Line in 39 of their last 64 away games (+9.20 Units / 11% ROI)
• The Washington Nationals have hit the Team Total Over in 34 of their last 57 away games (+7.65 Units / 11% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 52 of their last 84 games at home (+25.80 Units / 19% ROI)
• The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 51 of their last 84 games at home (+16.90 Units / 17% ROI)
• The Chicago Cubs have hit the Game Total Under in 64 of their last 117 games (+13.65 Units / 11% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 33 of their last 51 games at home (+12.00 Units / 19% ROI)
• The Chicago Cubs have hit the Moneyline in 42 of their last 64 games at home (+9.55 Units / 9% ROI)

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 1-0 against the Run Line (+1 Units / 74.07% ROI).

• 1-0 when betting on the Moneyline for +1.75 Units / 175% ROI
• 1-0 when betting on the total runs Over for +1 Units / 100% ROI
• 0-1 when betting on the total runs Under for -1.2 Units / -100% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 0-1 against the Run Line (-1 Units / -100% ROI).

• 0-1 when betting on the Moneyline for -2.05 Units / -100% ROI
• 1-0 when betting on the total runs Over for +1 Units / 100% ROI
• 0-1 when betting on the total runs Under for -1.2 Units / -100% ROI

Nationals Keys to the Game vs. the Cubs

The Nationals were just 11-43 (.200) when their opponents score in the first inning in the 2025 season — lowest in MLB; League Avg: .362.

The Nationals were just 64-79 (.444) when allowing 5 or more extra base hits in the 2025 season — 3rd lowest in MLB; League Avg: .535.

The Nationals were 8-5 (.615) when tied entering the 7th inning in the 2025 season — 5th best in MLB; League Avg: .500.

The Nationals were just 65-96 (.401) in the 2025 season — 3rd lowest in MLB; League Avg: .500.

Cubs Keys to the Game vs. the Nationals

The Cubs were 46-24 (.657) after a loss in the 2025 season — best in MLB; League Avg: .483.

The Cubs were 40-9 (.816) when they scored in the first inning in the 2025 season — best in MLB; League Avg: .636.

The Cubs were 48-6 (.889) when they had 10 or more hits in the 2025 season — best in MLB; League Avg: .743.

The Cubs are 72-19 (.791) when they’ve scored in the first inning since the 2024 season — best in MLB; League Avg: .638.

Nationals Hitting Stats & Trends

Nationals hitters had an OPS of just .640 (1,704 PA’s) against LHP in the 2025 season — 3rd lowest in MLB.

Nationals hitters slugged just .353 against LHP in the 2025 season — tied for 3rd lowest in MLB.

Nationals hitters drew walks in 7% of their PA’s against LHP in the 2025 season — lowest in MLB.

Nationals hitters struck out in 25% of their PA’s against LHP in the 2025 season — 3rd highest in MLB.

Cubs Hitting Stats & Trends

Cubs hitters had an OPS of .752 (1,589 PA’s) against LHP in the 2025 season — 5th best in MLB.

Cubs hitters slugged .434 against LHP in the 2025 season — 4th best in MLB.

27% of Cubs hitters strikeouts came on 95+ MPH fastballs in the 2025 season — 3rd highest in MLB.

Cubs hitters have put just 18% of their swings in play on the first pitch of at-bats in the postseason — lowest in MLB; League Avg: 34%.

Nationals Pitching Stats & Trends

Nationals pitchers had an ERA of 5.34 (1424.2 IP) in the 2025 season — 2nd highest in MLB.

The Nationals allowed 1.85 runs per game (299/162) in late innings in the 2025 season — highest in MLB.

Nationals pitchers had a strikeout rate of just 38% with two-strikes in the 2025 season — 2nd lowest in MLB.

The Nationals allowed 5.56 runs per game (900/162) in the 2025 season — 2nd highest in MLB.

Cubs Pitching Stats & Trends

Cubs pitchers walked 7% of batters in the 2025 season — best in MLB.

Cubs pitchers picked-off 27 runners in the 2025 season — most in MLB.

Cubs pitchers picked-off 25 runners from first base in the 2025 season — most in MLB.

Opponents had a miss rate of just 23% against Cubs pitchers in the 2025 season — 4th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Nationals vs Cubs and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.