Nationals vs Tigers Prediction, Odds & Player Prop Bets Today – MLB, Sep 22

Detroit Tigers' Parker Meadows reacts after hitting a double against the Oakland Athletics during the third inning of a baseball game Sunday, Sept. 24, 2023, in Oakland, Calif.
(AP Photo/Godofredo A. Vรกsquez)
Odds Boost This Week
  • The Tigers are -160 favorites vs the Nationals
  • Nationals vs Tigers Over / Under today: 8 Runs
  • Nationals / Tigers TV Channel: DSN | NATV

The Washington Nationals (+135) visit Comerica Park to take on the Detroit Tigers (-160) on September 22, 2026. First pitch is scheduled for 6:40 pm in Detroit, MI.

This season, the Nationals are 73-84 against the spread (ATS), while the Tigers are 75-76 ATS.

Nationals vs Tigers Starting Pitchers Today:

  • Nationals starting pitcher: Jackson Kent 1-4, 6.34 ERA
  • Tigers starting pitcher: Drew Anderson 5-6, 3.61 ERA

Nationals vs. Tigers Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Nationals+1.5 -160O 8 +100+135
Tigers -1.5 +135U 8 -120-160

Nationals vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Tuesday‘s MLB game with 55.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Nationals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Bets Today:

  • Keibert Ruiz has hit the Home Runs Over in 2 of his last 7 away games (+13.00 Units / 186% ROI)
  • Daylen Lile has hit the Hits Under in 14 of his last 20 away games (+12.90 Units / 53% ROI)
  • Abimelec Ortiz has hit the Total Bases Under in 18 of his last 25 games (+10.20 Units / 29% ROI)
  • Dylan Crews has hit the Runs Under in 20 of his last 25 away games (+10.10 Units / 22% ROI)
  • Abimelec Ortiz has hit the Singles Under in 19 of his last 25 games (+9.85 Units / 25% ROI)

And here are some favorite MLB player prop bets for Tigers players for Tuesday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

  • Dillon Dingler has hit the Runs Under in 21 of his last 25 games (+14.15 Units / 30% ROI)
  • Ben Malgeri has hit the Home Runs Over in 2 of his last 6 games at home (+13.50 Units / 225% ROI)
  • Javier Baez has hit the Singles Under in 20 of his last 25 games (+13.50 Units / 40% ROI)
  • Dillon Dingler has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+12.40 Units / 40% ROI)
  • Eduardo Valencia has hit the Hits Over in 16 of his last 20 games (+10.65 Units / 32% ROI)
  • The Washington Nationals have hit the Game Total Over in 14 of their last 21 games (+7.35 Units / 32% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Under in 19 of their last 30 away games (+6.15 Units / 17% ROI)
  • The Washington Nationals have hit the Team Total Over in 14 of their last 22 games (+5.40 Units / 21% ROI)
  • The Washington Nationals have hit the Moneyline in 6 of their last 9 games (+3.85 Units / 37% ROI)
  • The Washington Nationals have covered the 1st Five Innings (F5) Run Line in 13 of their last 22 games (+2.70 Units / 10% ROI)
  • The Detroit Tigers have hit the 1st Five Innings (F5) Moneyline in 27 of their last 45 games at home (+17.60 Units / 26% ROI)
  • The Detroit Tigers have covered the 1st Five Innings (F5) Run Line in 25 of their last 40 games at home (+9.35 Units / 20% ROI)
  • The Detroit Tigers have covered the Run Line in 13 of their last 19 games (+7.55 Units / 28% ROI)
  • The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 15 of their last 23 games at home (+6.90 Units / 26% ROI)
  • The Detroit Tigers have hit the Game Total Under in 22 of their last 40 games at home (+5.40 Units / 12% ROI)

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 87-68 against the Run Line (+5.9 Units / 2.8% ROI).

  • 73-84 when betting on the Moneyline for -0.4 Units / -0.24% ROI
  • 83-66 when betting on the total runs Over for +11 Units / 6.36% ROI
  • 66-83 when betting on the total runs Under for -24.85 Units / -14.4% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 75-76 against the Run Line (-4.65 Units / -2.32% ROI).

  • 74-83 when betting on the Moneyline for -20.15 Units / -10.42% ROI
  • 69-80 when betting on the total runs Over for -18.7 Units / -10.82% ROI
  • 80-69 when betting on the total runs Under for +4.4 Units / 2.55% ROI

Nationals Keys to the Game vs. the Tigers

The Nationals are just 58-20 (.744) when leading entering the 7th inning this season — lowest in MLB.

The Nationals are just 14-63 (.182) when scoring 4 or fewer runs this season — lowest in MLB.

The Nationals are just 35-26 (.574) when they’ve hit 2 or more home runs this season — 3rd lowest in MLB.

The Nationals are just 1-73 (.014) when trailing entering the 9th inning this season — lowest in MLB.

Tigers Keys to the Game vs. the Nationals

The Tigers are just 3-11 (.214) when tied entering the 7th inning this season — lowest in MLB.

The Tigers are just 64-40 (.615) when allowing 4 or fewer runs this season — 2nd lowest in MLB.

The Tigers are just 60-18 (.769) when leading entering the 7th inning this season — 2nd lowest in MLB.

The Tigers are just 4-10 (.286) when tied entering the 8th inning this season — 2nd lowest in MLB.

Nationals hitters are slugging .285 with two-strikes this season — tied for 2nd best in MLB.

The Nationals are batting .261 against LHP this season — tied for 3rd best in MLB.

Nationals hitters are slugging .438 against LHP this season — 3rd best in MLB.

Nationals hitters have an OBP of .335 (1,781 PA’s) against LHP this season — tied for 3rd best in MLB.

Tigers hitters have been successful in just 56% of their sacrifice bunt attempts this season — lowest in MLB.

Tigers hitters have chased 26% of pitches out of the zone against LHP this season — lowest in MLB.

The Tigers are batting just .133 on pitches out of the zone this season — 3rd lowest in MLB.

The Tigers have answered-back in just 23% of innings after an opponent scores in late innings this season — lowest in MLB.

The Nationals have allowed 1.87 runs per game (293/157) in late innings this season — highest in MLB.

The Nationals have allowed 5.51 runs per game (430/78) at home this season — 3rd highest in MLB.

Nationals pitchers have an ERA of 5.03 (711.0 IP) at home this season — 3rd highest in MLB.

Nationals pitchers have a strikeout rate of just 20% this season — 5th lowest in MLB.

Opponents have a groundball rate of 45% against Tigers pitchers this season — 2nd highest in MLB.

Tigers pitchers have an ERA of 3.30 (690.1 IP) at home this season — 2nd best in MLB.

Tigers pitchers have allowed a run just 27% of the time after their offense scores this season — 4th lowest in MLB.

The Tigers have allowed 3.71 runs per game (282/76) at home this season — 3rd best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.