• The Orioles are -110 favorites vs the Cardinals
• Orioles vs Cardinals Over / Under today: 8.5 Runs
• Orioles / Cardinals TV Channel: MASN | CATV

The Baltimore Orioles (-110) visit Busch Stadium to take on the St. Louis Cardinals (-110) on August 26, 2026. First pitch is scheduled for 7:45 pm in St. Louis, MO.

This season, the Orioles are against the spread (ATS), while the Cardinals are ATS.

Orioles vs Cardinals Starting Pitchers Today:

• Orioles starting pitcher: Kyle Bradish 7-12, 3.73 ERA
• Cardinals starting pitcher: Michael McGreevy 5-9, 3.58 ERA

Orioles vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Orioles vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Wednesday‘s MLB game with 54.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Orioles vs Cardinals and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

• Dylan Beavers has hit the Home Runs Over in 4 of his last 7 games (+23.10 Units / 330% ROI)
• Colton Cowser has hit the Singles Over in 15 of his last 25 away games (+16.15 Units / 65% ROI)
• Kyle Bradish has hit the Strikeouts Under in 14 of his last 15 games (+12.95 Units / 71% ROI)
• Gunnar Henderson has hit the Runs Over in 17 of his last 25 away games (+12.30 Units / 46% ROI)
• Pete Alonso has hit the Hits Over in 14 of his last 15 games (+11.40 Units / 35% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• Nolan Gorman has hit the Total Bases Under in 13 of his last 15 games (+11.15 Units / 62% ROI)
• Jordan Walker has hit the Home Runs Over in 4 of his last 10 games (+11.00 Units / 110% ROI)
• Nathan Church has hit the Hits Runs and RBIs Over in 17 of his last 25 games (+10.95 Units / 38% ROI)
• Ramon Urias has hit the Singles Under in 13 of his last 15 games at home (+10.40 Units / 47% ROI)
• JJ Wetherholt has hit the Hits Under in 12 of his last 20 games at home (+9.75 Units / 42% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the Team Total Over in 23 of their last 35 away games (+10.45 Units / 26% ROI)
• The Baltimore Orioles have covered the Run Line in 21 of their last 30 away games (+10.05 Units / 23% ROI)
• The Baltimore Orioles have hit the Game Total Under in 27 of their last 45 games (+8.90 Units / 18% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 21 of their last 40 away games (+8.15 Units / 19% ROI)
• The Baltimore Orioles have hit the Moneyline in 17 of their last 30 away games (+7.60 Units / 24% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 17 of their last 22 games (+11.55 Units / 46% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 26 of their last 50 games (+10.95 Units / 19% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 25 of their last 40 games at home (+9.80 Units / 22% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 20 of their last 30 games at home (+9.50 Units / 27% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 30 games at home (+8.80 Units / 24% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Cardinals vs Orioles Home Run Prop Bets Today

Cardinals vs Orioles Total Hits Prop Bets Today

Cardinals vs Orioles Strikeout Prop Bets Today

Orioles Keys to the Game vs. the Cardinals

The Orioles are just 2-5 (.286) when tied entering the 8th inning this season — 2nd lowest in MLB.

The Orioles are just 4-9 (.308) when tied entering the 7th inning this season — 5th lowest in MLB.

The Orioles are just 4-137 (.028) when trailing entering the 9th inning since the 2025 season — 3rd lowest in MLB.

The Orioles are just 13-21 (.382) when tied entering the 7th inning since the 2025 season — 3rd lowest in MLB.

Cardinals Keys to the Game vs. the Orioles

The Cardinals are just 25-14 (.641) when they’ve had 10 or more hits this season — 2nd lowest in MLB.

The Cardinals are just 6-12 (.333) when tied entering the 8th inning this season — tied for 4th lowest in MLB.

The Cardinals are just 5-47 (.096) when trailing entering the 7th inning this season — 4th lowest in MLB.

The Cardinals are just 13-23 (.361) when tied entering the 8th inning since the 2025 season — 2nd lowest in MLB.

Orioles Hitting Stats & Trends

Orioles hitters have struck out in 26% of their PA’s against LHP this season — tied for highest in MLB.

Orioles hitters have a Hard-Hit Rate of 51% on pitches 95 mph or greater this season — best in MLB.

The Orioles have an average Exit Velocity of 90.1 MPH this season — best in MLB.

Orioles hitters have a Hard-Hit Rate of 43% this season — best in MLB.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 19% of their PA’s against LHP this season — 3rd best in MLB.

Cardinals hitters are slugging just .361 at home this season — 2nd lowest in MLB.

Cardinals hitters have struck out in just 21% of their PA’s this season — tied for 4th best in MLB.

Cardinals hitters have an OPS of just .667 (2,445 PA’s) at home this season — 2nd lowest in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers have allowed a run 36% of the time after their offense scores this season — 2nd highest in MLB.

Orioles pitchers are throwing just 3.82 pitches per plate appearance this season — tied for 5th lowest in MLB.

Orioles pitchers has induced two-strike counts to 50% of batters they faced (2,538/5,033 PA’s) this season — 4th lowest in MLB.

Orioles pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2025 season — 3rd highest in MLB.

Cardinals Pitching Stats & Trends

The Cardinals pitchers have allowed their opponents to score first in just 32% of their games on the road this season — lowest in MLB.

Opponents have a miss rate of just 23% against Cardinals pitchers this season — 4th lowest in MLB.

Cardinals pitchers have induced opposing hitters to ground into 118 double plays in 1,005 opportunities (12%) this season — best in MLB.

Opponents have a groundball rate of 45% against Cardinals pitchers this season — tied for 4th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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