• The Orioles are -125 favorites vs the Cardinals
• Orioles vs Cardinals Over / Under today: 8 Runs
• Orioles / Cardinals TV Channel: MASN | CATV

The Baltimore Orioles (-125) visit Busch Stadium to take on the St. Louis Cardinals (+105) on August 27, 2026. First pitch is scheduled for 2:15 pm in St. Louis, MO.

This season, the Orioles are 65-68 against the spread (ATS), while the Cardinals are 72-59 ATS.

Orioles vs Cardinals Starting Pitchers Today:

• Orioles starting pitcher: Trevor Rogers 9-8, 4.16 ERA
• Cardinals starting pitcher: Undecided 0-0, 0.00 ERA

Orioles vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Orioles vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Thursday‘s MLB game with 54.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Orioles vs Cardinals and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Orioles players for Thursday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

• Dylan Beavers has hit the Home Runs Over in 4 of his last 8 games (+22.10 Units / 276% ROI)
• Gunnar Henderson has hit the Runs Over in 15 of his last 20 away games (+13.90 Units / 67% ROI)
• Leody Taveras has hit the Hits Runs and RBIs Over in 18 of his last 25 away games (+12.15 Units / 41% ROI)
• Pete Alonso has hit the Total Bases Over in 12 of his last 15 games (+10.80 Units / 71% ROI)
• Pete Alonso has hit the Singles Over in 17 of his last 25 games (+10.25 Units / 40% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Thursday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• Blaze Jordan has hit the Runs Under in his last 20 games at home (+20.00 Units / 44% ROI)
• Bryan Torres has hit the Singles Over in 12 of his last 15 games (+11.10 Units / 73% ROI)
• Jimmy Crooks III has hit the Hits Under in 17 of his last 25 games at home (+11.10 Units / 42% ROI)
• Jimmy Crooks III has hit the Hits Runs and RBIs Under in 18 of his last 25 games at home (+10.55 Units / 32% ROI)
• Jimmy Crooks III has hit the Total Bases Under in 17 of his last 25 games at home (+10.35 Units / 38% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the Team Total Over in 21 of their last 30 away games (+11.75 Units / 34% ROI)
• The Baltimore Orioles have covered the Run Line in 21 of their last 30 away games (+10.95 Units / 26% ROI)
• The Baltimore Orioles have hit the Moneyline in 18 of their last 30 away games (+9.60 Units / 30% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Over in their last 8 away games (+8.30 Units / 90% ROI)
• The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 25 of their last 40 away games (+8.25 Units / 17% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 26 of their last 50 games (+12.05 Units / 21% ROI)
• The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 17 of their last 23 games (+10.55 Units / 40% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 22 of their last 35 games at home (+8.90 Units / 23% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 22 of their last 35 games at home (+8.45 Units / 21% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 19 of their last 30 games at home (+6.20 Units / 17% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 69-63 against the Run Line (+0.95 Units / 0.54% ROI).

• 65-68 when betting on the Moneyline for -7.55 Units / -4.86% ROI
• 67-62 when betting on the total runs Over for -1.2 Units / -0.82% ROI
• 62-67 when betting on the total runs Under for -11 Units / -7.55% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 72-59 against the Run Line (-2.1 Units / -1.12% ROI).

• 66-68 when betting on the Moneyline for +3.4 Units / 2.34% ROI
• 58-70 when betting on the total runs Over for -19.35 Units / -13.11% ROI
• 70-58 when betting on the total runs Under for +6 Units / 4.07% ROI

Cardinals vs Orioles Home Run Prop Bets Today

Cardinals vs Orioles Total Hits Prop Bets Today

Cardinals vs Orioles Strikeout Prop Bets Today

Orioles Keys to the Game vs. the Cardinals

The Orioles are just 4-137 (.028) when trailing entering the 9th inning since the 2025 season — tied for 3rd lowest in MLB.

The Orioles are just 14-21 (.400) when tied entering the 7th inning since the 2025 season — tied for 3rd lowest in MLB.

The Orioles are just 9-14 (.391) when tied entering the 8th inning since the 2025 season — 4th lowest in MLB.

The Orioles are just 20-75 (.211) when allowing 2 or more home runs since the 2025 season — 3rd lowest in MLB.

Cardinals Keys to the Game vs. the Orioles

The Cardinals are just 25-15 (.625) when they’ve had 10 or more hits this season — 2nd lowest in MLB.

The Cardinals are just 6-13 (.316) when tied entering the 8th inning this season — 3rd lowest in MLB.

The Cardinals are just 5-47 (.096) when trailing entering the 7th inning this season — 4th lowest in MLB.

The Cardinals are just 13-24 (.351) when tied entering the 8th inning since the 2025 season — 2nd lowest in MLB.

Orioles Hitting Stats & Trends

Orioles hitters have struck out in 26% of their PA’s against LHP this season — tied for highest in MLB.

Orioles hitters have a Hard-Hit Rate of 51% on pitches 95 mph or greater this season — best in MLB.

Orioles hitters are slugging just .512 on the first pitch of at-bats this season — 4th lowest in MLB.

The Orioles are batting just .234 at home this season — tied for 5th lowest in MLB.

Cardinals Hitting Stats & Trends

Cardinals hitters are slugging just .491 with the pitcher behind in the count this season — lowest in MLB.

Cardinals hitters have an OPS of just .693 (3,514 PA’s) against RHP this season — 4th lowest in MLB.

Cardinals hitters are slugging just .379 against RHP this season — tied for 2nd lowest in MLB.

Cardinals hitters have struck out in just 19% of their PA’s against LHP this season — 3rd best in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers have allowed a run 36% of the time after their offense scores this season — 2nd highest in MLB.

Opponents are hitting .254 against Orioles pitchers this season — tied for 5th highest in MLB.

Orioles pitchers has induced two-strike counts to 51% of batters they faced (2,563/5,075 PA’s) this season — 4th lowest in MLB.

Orioles pitchers are throwing just 3.82 pitches per plate appearance this season — tied for 5th lowest in MLB.

Cardinals Pitching Stats & Trends

The Cardinals pitchers have allowed their opponents to score first in just 32% of their games on the road this season — lowest in MLB.

Cardinals pitchers have induced opposing hitters to ground into 119 double plays in 1,012 opportunities (12%) this season — best in MLB.

Opponents have a miss rate of just 23% against Cardinals pitchers this season — 4th lowest in MLB.

Cardinals pitchers have a strikeout rate of just 19% with runners in scoring position this season — 4th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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