• The Orioles are +100 favorites vs the Guardians
• Orioles vs Guardians Over / Under today: 7 Runs
• Orioles / Guardians TV Channel: GDTV | MASN

The Baltimore Orioles (+100) visit Progressive Field to take on the Cleveland Guardians (-120) on April 19, 2026. First pitch is scheduled for 1:40 pm in Cleveland, OH.

This season, the Orioles are 10-11 against the spread (ATS), while the Guardians are 12-10 ATS.

Orioles vs Guardians Starting Pitchers Today:

• Orioles starting pitcher: Trevor Rogers 2-1, 3.09 ERA
• Guardians starting pitcher: Joey Cantillo 1-0, 2.66 ERA

Orioles vs. Guardians Odds, Run Line, Over/Under & Moneyline

Orioles vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Sunday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Orioles vs Guardians and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Orioles players for Sunday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

• Jeremiah Jackson has hit the Home Runs Over in 4 of his last 8 games (+29.50 Units / 369% ROI)
• Trevor Rogers has hit the Earned Runs Under in 16 of his last 20 games (+11.45 Units / 42% ROI)
• Pete Alonso has hit the Singles Under in 13 of his last 15 games (+10.40 Units / 51% ROI)
• Pete Alonso has hit the Runs Under in 19 of his last 25 away games (+10.15 Units / 28% ROI)
• Trevor Rogers has hit the Hits Allowed Under in 15 of his last 20 games (+9.80 Units / 38% ROI)

And here are some favorite MLB player prop bets for Guardians players for Sunday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

• Brayan Rocchio has hit the Home Runs Over in 3 of his last 10 games at home (+28.00 Units / 280% ROI)
• Daniel Schneemann has hit the Hits Runs and RBIs Over in 9 of his last 10 games (+8.25 Units / 66% ROI)
• Daniel Schneemann has hit the Total Bases Over in 9 of his last 10 games (+7.90 Units / 61% ROI)
• Jose Ramirez has hit the Hits Under in 6 of his last 8 games at home (+7.75 Units / 97% ROI)
• Jose Ramirez has hit the Walks Over in 5 of his last 6 games (+7.00 Units / 117% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the Team Total Under in 25 of their last 40 games (+8.35 Units / 17% ROI)
• The Baltimore Orioles have hit the Game Total Under in 27 of their last 45 games (+8.05 Units / 16% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 27 of their last 45 games (+7.45 Units / 14% ROI)
• The Baltimore Orioles have hit the Moneyline in 16 of their last 30 away games (+5.00 Units / 15% ROI)
• The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 17 of their last 30 away games (+1.95 Units / 5% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Moneyline in 33 of their last 50 games (+19.55 Units / 34% ROI)
• The Cleveland Guardians have covered the Run Line in 31 of their last 50 games (+14.20 Units / 22% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 23 of their last 50 games (+10.55 Units / 18% ROI)
• The Cleveland Guardians have hit the Game Total Under in 30 of their last 50 games (+10.10 Units / 18% ROI)
• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 30 of their last 50 games (+9.45 Units / 16% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 8-13 against the Run Line (-6.4 Units / -24.33% ROI).

• 10-11 when betting on the Moneyline for -3.3 Units / -12.48% ROI
• 11-10 when betting on the total runs Over for -0.05 Units / -0.22% ROI
• 10-11 when betting on the total runs Under for -2.3 Units / -9.87% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 12-10 against the Run Line (+1.8 Units / 6.39% ROI).

• 12-10 when betting on the Moneyline for +4.4 Units / 18.14% ROI
• 10-12 when betting on the total runs Over for -3 Units / -12.47% ROI
• 12-10 when betting on the total runs Under for +0.85 Units / 3.47% ROI

Guardians vs Orioles Home Run Prop Bets Today

Guardians vs Orioles Total Hits Prop Bets Today

Guardians vs Orioles Strikeout Prop Bets Today

Orioles Keys to the Game vs. the Guardians

The Orioles were just 1-77 (.013) when trailing entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .043.

The Orioles are just 1-86 (.011) when trailing entering the 9th inning since the 2025 season — tied for 2nd lowest in MLB; League Avg: .043.

The Orioles are just 0-9 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .046.

The Orioles were 65-20 (.765) when they allowed 4 or fewer runs in the 2025 season — 5th best in MLB; League Avg: .714.

Guardians Keys to the Game vs. the Orioles

The Guardians are just 2-9 (.182) after a win this season — lowest in MLB; League Avg: .534.

The Guardians are 36-4 (.878) when they’ve had 10 or more hits since the 2025 season — 2nd best in MLB; League Avg: .749.

The Guardians are just 0-7 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .129.

The Guardians were just 73-5 (.936) when leading entering the 9th inning in the 2025 season — 5th lowest in MLB; League Avg: .956.

Orioles Hitting Stats & Trends

The Orioles are batting just .250 on the first pitch of at-bats this season — tied for lowest in MLB.

Orioles hitters are slugging just .330 on the first pitch of at-bats this season — lowest in MLB.

Orioles hitters have struck out in 25% of their PA’s against RHP this season — 3rd highest in MLB.

Orioles hitters slugged just .189 on pitches out of the zone in the 2025 season — 5th lowest in MLB.

Guardians Hitting Stats & Trends

Guardians hitters have put just 26% of their swings in play on the first pitch of at-bats this season — lowest in MLB.

The Guardians batted just .226 in the 2025 season — 2nd lowest in MLB.

7% of Guardians’ hitters plate appearances have lasted only one pitch (56/806 PA’s) this season — lowest in MLB.

The Guardians are batting just .191 in righty-righty matchups since the 2025 season — lowest in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers walked 10% of batters when facing the leadoff batter in the inning in the 2025 season — 2nd highest in MLB.

Orioles pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2025 season — 2nd highest in MLB.

Opponents have a miss rate of 28% against Orioles pitchers this season — tied for 4th best in MLB.

Opponents had a groundball batting average of .269 against Orioles pitchers in the 2025 season — 3rd highest in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 38% in close and late situations this season — best in MLB.

Guardians pitchers have an ERA of 2.51 (498.1 IP) against division opponents since the 2025 season — best in MLB.

Guardians pitchers had an ERA of 3.72 (706.0 IP) on the road in the 2025 season — tied for best in MLB.

Opponents had a chase percentage of just 26% against the Guardians pitchers in the 2025 season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Orioles vs Guardians and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.