Orioles vs Marlins Prediction, Odds & Player Prop Bets Today – MLB, May 6

Miami Marlins' Kyle Stowers strikes out swinging during the second inning of a baseball game against the Philadelphia Phillies, Thursday, Sept. 5, 2024, in Miami.
(AP Photo/Lynne Sladky)
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  • The Marlins are -135 favorites vs the Orioles
  • Orioles vs Marlins Over / Under today: 8.5 Runs
  • Orioles / Marlins TV Channel: MASN | MATV

The Baltimore Orioles (+110) visit loanDepot park to take on the Miami Marlins (-135) on May 6, 2026. First pitch is scheduled for 6:40 pm in Miami, FL.

This season, the Orioles are 16-20 against the spread (ATS), while the Marlins are 17-19 ATS.

Orioles vs Marlins Starting Pitchers Today:

  • Orioles starting pitcher: Brandon Young 2-1, 6.14 ERA
  • Marlins starting pitcher: Eury Perez 2-3, 4.50 ERA

Orioles vs. Marlins Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Orioles+1.5 -200O 8.5 -110+110
Marlins -1.5 +165U 8.5 -110-135

Orioles vs Marlins Prediction for Today’s Game

Based on recent trends the model predicts the Marlins will win Wednesday‘s MLB game with 52.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

  • Coby Mayo has hit the Home Runs Over in 3 of his last 10 games (+13.30 Units / 133% ROI)
  • Gunnar Henderson has hit the Walks Under in 17 of his last 20 games (+11.95 Units / 30% ROI)
  • Blaze Alexander has hit the Hits Runs and RBIs Under in 14 of his last 20 games (+7.95 Units / 30% ROI)
  • Leody Taveras has hit the Total Bases Over in 14 of his last 20 games (+7.55 Units / 27% ROI)
  • Pete Alonso has hit the Runs Over in 15 of his last 25 games (+7.45 Units / 30% ROI)

And here are some favorite MLB player prop bets for Marlins players for Wednesday‘s game, looking at profitable historical betting trends:

Best Marlins Player Prop Best Bets Today:

  • Liam Hicks has hit the Home Runs Over in 4 of his last 8 games (+33.50 Units / 419% ROI)
  • Graham Pauley has hit the Singles Under in 21 of his last 25 games (+13.90 Units / 28% ROI)
  • Jakob Marsee has hit the Hits Under in 15 of his last 25 games at home (+12.70 Units / 48% ROI)
  • Xavier Edwards has hit the Walks Over in 12 of his last 20 games (+12.20 Units / 61% ROI)
  • Otto Lopez has hit the Hits Runs and RBIs Over in 19 of his last 25 games (+11.55 Units / 36% ROI)
  • The Baltimore Orioles have hit the Game Total Over in 20 of their last 25 games (+14.60 Units / 53% ROI)
  • The Baltimore Orioles have hit the Team Total Over in 16 of their last 25 games (+6.20 Units / 22% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 16 away games (+5.80 Units / 32% ROI)
  • The Baltimore Orioles have covered the Run Line in 7 of their last 14 games (+1.35 Units / 8% ROI)
  • The Baltimore Orioles have hit the Moneyline in 19 of their last 40 away games (+1.35 Units / 3% ROI)
  • The Miami Marlins have hit the Game Total Over in 21 of their last 35 games (+7.60 Units / 20% ROI)
  • The Miami Marlins have hit the 1st Five Innings (F5) Moneyline in 9 of their last 15 games (+6.10 Units / 34% ROI)
  • The Miami Marlins have hit the 1st Five Innings (F5) Team Total Over in 29 of their last 50 games (+6.10 Units / 10% ROI)
  • The Miami Marlins have covered the Run Line in 10 of their last 15 games (+5.50 Units / 28% ROI)
  • The Miami Marlins have hit the Moneyline in 26 of their last 50 games (+5.45 Units / 9% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 15-21 against the Run Line (-6.65 Units / -14.76% ROI).

  • 16-20 when betting on the Moneyline for -7 Units / -16.07% ROI
  • 25-11 when betting on the total runs Over for +12.85 Units / 32.29% ROI
  • 11-25 when betting on the total runs Under for -16.35 Units / -41.44% ROI

Marlins Against the Spread (ATS) Record

Against the spread this season, the Marlins are 17-19 against the Run Line (-3.6 Units / -7.79% ROI).

  • 16-20 when betting on the Moneyline for -2.35 Units / -5.33% ROI
  • 21-13 when betting on the total runs Over for +6.5 Units / 16.29% ROI
  • 13-21 when betting on the total runs Under for -10 Units / -25.45% ROI

Marlins vs Orioles Home Run Prop Bets Today

Yes
Pete Alonso +375
Gunnar Henderson +390
Kyle Stowers +425
Taylor Ward +550
Adley Rutschman +600

Marlins vs Orioles Total Hits Prop Bets Today

Over Under
Otto Lopez 0.5 -275 0.5 +195
Liam Hicks 0.5 -220 0.5 +165
Kyle Stowers 0.5 -210 0.5 +155
Gunnar Henderson 0.5 -210 0.5 +155
Jakob Marsee 0.5 -185 0.5 +135

Marlins vs Orioles Strikeout Prop Bets Today

Over Under
Owen Caissie 0.5 -275 0.5 +195
Pete Alonso 0.5 -250 0.5 +185
Taylor Ward 0.5 -250 0.5 +180
Connor Norby 0.5 -250 0.5 +185
Leody Taveras 0.5 -235 0.5 +170

Orioles Keys to the Game vs. the Marlins

The Orioles are just 3-16 (.158) when scoring 4 or fewer runs this season — lowest in MLB; League Avg: .275.

The Orioles are just 19-48 (.284) when their opponents score in the first inning since the 2025 season — 5th lowest in MLB; League Avg: .365.

The Orioles are just 2-94 (.021) when trailing entering the 9th inning since the 2025 season — tied for 3rd lowest in MLB; League Avg: .045.

The Orioles are just 6-10 (.375) when tied entering the 8th inning since the 2025 season — 5th lowest in MLB; League Avg: .500.

Marlins Keys to the Game vs. the Orioles

The Marlins are just 1-17 (.056) when allowing 5 or more runs this season — lowest in MLB; League Avg: .216.

The Marlins are just 12-3 (.800) when leading entering the 8th inning this season — 4th lowest in MLB; League Avg: .890.

The Marlins are just 50-71 (.413) vs the bottom 10 runs allowed teams since the 2024 season Today, they face the Orioles (28th runs allowed).

The Marlins are just 1-5 (.167) when allowing 2 or more home runs this season — 5th lowest in MLB; League Avg: .301.

Orioles hitters are slugging just .342 on the first pitch of at-bats this season — lowest in MLB.

The Orioles are batting just .242 on the first pitch of at-bats this season — lowest in MLB.

The Orioles are batting just .117 on pitches out of the zone this season — 2nd lowest in MLB.

Orioles hitters are slugging just .132 on pitches out of the zone this season — lowest in MLB.

Marlins hitters have put 40% of their swings in play on the first pitch of at-bats since the 2025 season — highest in MLB.

Marlins hitters have 9 extra-base hits out of 44 total hits (just 20%) on the first pitch of at-bats this season — lowest in MLB.

Marlins hitters are slugging just .324 against LHP this season — 4th lowest in MLB.

Marlins hitters are slugging just .406 on the first pitch of at-bats this season — 2nd lowest in MLB.

Orioles pitchers have an ERA of 9.00 (59.0 IP) against division opponents this season — highest in MLB.

Orioles pitchers have an ERA of 8.08 (59.0 IP) over the past seven days (7 games) — highest in MLB.

The Orioles have allowed 8.57 runs per game (60/7) over the past seven days (7 games) — highest in MLB.

Orioles pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2025 season — 2nd highest in MLB.

The Marlins allowed 6.04 runs per game (489/81) at home in the 2024 season — highest in MLB.

Marlins pitchers have allowed 30 home runs this season — tied for 4th fewest in MLB.

Marlins pitchers have an ERA of 3.25 (191.0 IP) at home this season — 5th best in MLB.

Marlins pitchers have 68 three-pitch strikeouts this season — tied for 2nd most in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.