• The Orioles are -150 favorites vs the Nationals
• Orioles vs Nationals Over / Under today: 9 Runs
• Orioles / Nationals TV Channel: MASN | NATV | WTTG

The Baltimore Orioles (-150) visit Nationals Park to take on the Washington Nationals (+125) on May 15, 2026. First pitch is scheduled for 6:45 pm in Washington, D.C., DC.

This season, the Orioles are 20-24 against the spread (ATS), while the Nationals are 26-17 ATS.

Orioles vs Nationals Starting Pitchers Today:

• Orioles starting pitcher: Shane Baz 1-4, 5.36 ERA
• Nationals starting pitcher: Zack Littell 1-4, 6.94 ERA

Orioles vs. Nationals Odds, Run Line, Over/Under & Moneyline

Orioles vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Friday‘s MLB game with 59.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Orioles players for Friday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

• Taylor Ward has hit the Walks Over in 20 of his last 25 games (+15.85 Units / 58% ROI)
• Shane Baz has hit the Walks Allowed Over in 14 of his last 15 away games (+12.85 Units / 56% ROI)
• Taylor Ward has hit the Total Bases Under in 13 of his last 15 games (+11.65 Units / 48% ROI)
• Pete Alonso has hit the Home Runs Over in 4 of his last 8 away games (+11.10 Units / 139% ROI)
• Pete Alonso has hit the Hits Over in 13 of his last 15 away games (+10.30 Units / 37% ROI)

And here are some favorite MLB player prop bets for Nationals players for Friday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

• Keibert Ruiz has hit the Home Runs Over in 2 of his last 4 games (+16.00 Units / 400% ROI)
• Luis Garcia has hit the Hits Under in 16 of his last 25 games (+13.06 Units / 42% ROI)
• James Wood has hit the Singles Under in 20 of his last 25 games (+12.65 Units / 33% ROI)
• James Wood has hit the Hits Runs and RBIs Over in 14 of his last 20 games at home (+7.85 Units / 34% ROI)
• Luis Garcia has hit the Total Bases Under in 9 of his last 10 games at home (+7.30 Units / 44% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the Game Total Over in 10 of their last 11 away games (+8.90 Units / 72% ROI)
• The Baltimore Orioles have hit the Team Total Under in 6 of their last 7 games (+4.95 Units / 68% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 5 of their last 6 games (+4.30 Units / 66% ROI)
• The Baltimore Orioles have covered the Run Line in 12 of their last 22 games (+2.90 Units / 10% ROI)
• The Baltimore Orioles have hit the Moneyline in 3 of their last 5 games (+1.50 Units / 28% ROI)

Nationals Best Bets Today:

• The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 32 of their last 45 games (+17.60 Units / 32% ROI)
• The Washington Nationals have hit the Game Total Over in 31 of their last 50 games (+12.75 Units / 23% ROI)
• The Washington Nationals have covered the 1st Five Innings (F5) Run Line in 18 of their last 24 games (+11.20 Units / 38% ROI)
• The Washington Nationals have hit the Team Total Over in 31 of their last 50 games (+9.10 Units / 16% ROI)
• The Washington Nationals have hit the 1st Five Innings (F5) Moneyline in 13 of their last 24 games (+8.05 Units / 32% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 20-24 against the Run Line (-5.1 Units / -9.1% ROI).

• 20-24 when betting on the Moneyline for -6.75 Units / -12.93% ROI
• 26-18 when betting on the total runs Over for +6 Units / 12.31% ROI
• 18-26 when betting on the total runs Under for -10.45 Units / -21.73% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 26-17 against the Run Line (+4.25 Units / 7% ROI).

• 21-23 when betting on the Moneyline for +6.05 Units / 13.57% ROI
• 28-14 when betting on the total runs Over for +12.9 Units / 26.68% ROI
• 14-28 when betting on the total runs Under for -16.7 Units / -34.43% ROI

Nationals vs Orioles Home Run Prop Bets Today

Nationals vs Orioles Total Hits Prop Bets Today

Nationals vs Orioles Strikeout Prop Bets Today

Orioles Keys to the Game vs. the Nationals

The Orioles are just 5-20 (.200) when scoring 4 or fewer runs this season — tied for 4th lowest in MLB; League Avg: .279.

The Orioles are 6-1 (.857) when they’ve scored in the first inning this season — 2nd best in MLB; League Avg: .624.

The Orioles are just 2-97 (.020) when trailing entering the 9th inning since the 2025 season — tied for 3rd lowest in MLB; League Avg: .045.

The Orioles are just 15-61 (.197) when allowing 2 or more home runs since the 2025 season — 5th lowest in MLB; League Avg: .300.

Nationals Keys to the Game vs. the Orioles

The Nationals are just 6-13 (.316) at home this season — lowest in MLB; League Avg: .543.

The Nationals are just 14-5 (.737) when leading entering the 7th inning this season — 3rd lowest in MLB; League Avg: .865.

The Nationals are just 0-21 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .051.

The Nationals are 16-3 (.842) when allowing 4 or fewer runs this season — 3rd best in MLB; League Avg: .721.

Orioles Hitting Stats & Trends

The Orioles are batting just .254 on the first pitch of at-bats this season — lowest in MLB.

Orioles hitters are slugging just .379 on the first pitch of at-bats this season — lowest in MLB.

The Orioles are batting just .149 with two-strikes this season — tied for 2nd lowest in MLB.

Orioles hitters have struck out in 25% of their PA’s against LHP this season — 5th highest in MLB.

Nationals Hitting Stats & Trends

The Nationals are batting just .176 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

The Nationals have scored 1.98 runs per game (87/44) in late innings this season — best in MLB.

Nationals hitters have an OPS of .781 (507 PA’s) against LHP this season — best in MLB.

Nationals hitters have an OBP of .267 (908 PA’s) with two-strikes this season — tied for 2nd best in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers have an ERA of 7.01 (86.0 IP) against division opponents this season — highest in MLB.

Orioles pitchers have an ERA of 5.27 (172.1 IP) on the road this season — 3rd highest in MLB.

Orioles pitchers have an ERA of 4.60 (389.2 IP) this season — tied for 5th highest in MLB.

Orioles pitchers have a strikeout rate of 28% in close and late situations this season — 4th best in MLB.

Nationals Pitching Stats & Trends

Nationals pitchers have a strikeout rate of just 36% with two-strikes this season — lowest in MLB.

Opponents have a miss rate of just 22% against Nationals pitchers this season — lowest in MLB.

Nationals pitchers have a strikeout rate of just 19% with runners in scoring position this season — 3rd lowest in MLB.

Nationals pitchers have a strikeout rate of just 19% this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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