Orioles vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Apr 3

Pittsburgh Pirates' Spencer Horwitz rounds the bases after hitting a solo home run in the seventh inning of a baseball game against the Atlanta Braves, Friday, Sept. 26, 2025, in Atlanta. (AP Photo/Colin Hubbard)
(AP Photo/Colin Hubbard)
New Player OfferOdds Boost Today
  • The Orioles are -125 favorites vs the Pirates
  • Orioles vs Pirates Over / Under today: 8.5 Runs
  • Orioles / Pirates TV Channel: MASN | SNPT

The Baltimore Orioles (-125) visit PNC Park to take on the Pittsburgh Pirates (+105) on April 3, 2026. First pitch is scheduled for 4:12 pm in Pittsburgh, PA.

This season, the Orioles are against the spread (ATS), while the Pirates are ATS.

Orioles vs Pirates Starting Pitchers Today:

  • Orioles starting pitcher: Kyle Bradish 0-1, 3.86 ERA
  • Pirates starting pitcher: Mitch Keller 0-0, 0.00 ERA

Orioles vs. Pirates Odds, Run Line, Over/Under & Moneyline

Orioles vs Pirates Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Friday‘s MLB game with 53.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Orioles vs Pirates and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Orioles players for Friday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

  • Coby Mayo has hit the Home Runs Over in 4 of his last 9 away games (+21.60 Units / 240% ROI)
  • Pete Alonso has hit the Hits Over in 18 of his last 20 games (+14.85 Units / 34% ROI)
  • Taylor Ward has hit the Walks Under in 20 of his last 25 games (+11.35 Units / 24% ROI)
  • Coby Mayo has hit the Runs Over in 6 of his last 7 away games (+9.70 Units / 139% ROI)
  • Colton Cowser has hit the Singles Under in his last 9 away games (+9.00 Units / 45% ROI)

And here are some favorite MLB player prop bets for Pirates players for Friday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

  • Ryan O’Hearn has hit the Total Bases Over in 14 of his last 15 games (+13.35 Units / 64% ROI)
  • Ryan O’Hearn has hit the Hits Over in 14 of his last 15 games (+12.60 Units / 52% ROI)
  • Ryan O’Hearn has hit the Singles Over in 17 of his last 25 games (+12.00 Units / 47% ROI)
  • Ryan O’Hearn has hit the Home Runs Over in 2 of his last 5 games (+10.50 Units / 210% ROI)
  • Bryan Reynolds has hit the Walks Over in 7 of his last 9 games at home (+9.70 Units / 108% ROI)
  • The Baltimore Orioles have hit the Game Total Under in 87 of their last 141 games (+30.03 Units / 19% ROI)
  • The Baltimore Orioles have hit the Team Total Under in 84 of their last 142 games (+17.65 Units / 10% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 39 away games (+10.75 Units / 23% ROI)
  • The Baltimore Orioles have hit the Moneyline in 59 of their last 113 games (+9.85 Units / 8% ROI)
  • The Baltimore Orioles have covered the Run Line in 45 of their last 76 games (+8.05 Units / 8% ROI)
  • The Pittsburgh Pirates have hit the Game Total Under in 88 of their last 150 games (+27.90 Units / 17% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 92 of their last 151 games (+26.80 Units / 15% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 77 of their last 124 games (+24.60 Units / 15% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 30 of their last 62 games at home (+14.29 Units / 18% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 37 of their last 62 games at home (+13.10 Units / 18% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are against the Run Line ( Units / ROI).

  • away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • away total over record when betting on the total runs Over for over units Units / over ROI ROI
  • away total under record when betting on the total runs Under for under units Units / under ROI ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Orioles Keys to the Game vs. the Pirates

The Orioles were just 1-77 (.013) when trailing entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .043.

The Orioles were just 12-51 (.190) when allowing 10 or more hits in the 2025 season — 5th lowest in MLB; League Avg: .256.

The Orioles were just 10-67 (.130) when they allowed 5 or more runs in the 2025 season — 4th lowest in MLB; League Avg: .202.

The Orioles were 65-20 (.765) when they allowed 4 or fewer runs in the 2025 season — 5th best in MLB; League Avg: .714.

Pirates Keys to the Game vs. the Orioles

The Pirates are just 14-88 (.137) when allowing 10 or more hits since the 2024 season — 2nd lowest in MLB; League Avg: .252.

The Pirates were just 5-65 (.071) when trailing entering the 7th inning in the 2025 season — 3rd lowest in MLB; League Avg: .124.

The Pirates were just 7-43 (.140) when allowing 10 or more hits in the 2025 season — 2nd lowest in MLB; League Avg: .256.

The Pirates were just 71-91 (.438) in the 2025 season — 5th lowest in MLB; League Avg: .500.

Orioles hitters are slugging .723 on pitches 95 mph or greater this season — best in MLB.

The Orioles are batting .329 with two outs this season — 2nd best in MLB.

Orioles hitters have an OPS of just .671 (3,064 PA’s) on the road since the 2025 season — 4th lowest in MLB.

Orioles hitters have an OBP of just .300 (3,064 PA’s) on the road since the 2025 season — tied for 5th lowest in MLB.

Pirates hitters had an OPS of just .622 (3,034 PA’s) on the road in the 2025 season — 2nd lowest in MLB.

Pirates hitters slugged just .186 in lefty-lefty matchups in the 2025 season — lowest in MLB.

The Pirates batted just .121 in lefty-lefty matchups in the 2025 season — lowest in MLB.

The Pirates batted just .219 against LHP in the 2025 season — 2nd lowest in MLB.

Orioles pitchers have walked 10% of batters when facing the leadoff batter in the inning since the 2025 season — 2nd highest in MLB.

Orioles pitchers walked 10% of batters when facing the leadoff batter in the inning in the 2025 season — 2nd highest in MLB.

In games when their opponents scored three or more runs in an inning, the Orioles won just 11% of the time in the 2025 season — lowest in MLB.

Opponents have a groundball rate of just 39% against Orioles pitchers this season — 5th lowest in MLB.

Pirates pitchers have walked 22% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Pirates pitchers have walked 14% of batters this season — 2nd highest in MLB.

Pirates pitchers walked 7% of batters when facing the leadoff batter in the inning in the 2025 season — 5th best in MLB.

Pirates pitchers won only 14% of games in which they allowed their opponent to score in three different innings in the 2025 season — 2nd lowest in MLB.

More MLB Reading:


Bet now on Orioles vs Pirates and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.

About the Author Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.