• The Red Sox are -140 favorites vs the Orioles
• Orioles vs Red Sox Over / Under today: 8.5 Runs
• Orioles / Red Sox TV Channel: NESN | MASN

The Baltimore Orioles (+115) visit Fenway Park to take on the Boston Red Sox (-140) on July 21, 2026. First pitch is scheduled for 7:10 pm in Boston, MA.

This season, the Orioles are against the spread (ATS), while the Red Sox are ATS.

Orioles vs Red Sox Starting Pitchers Today:

• Orioles starting pitcher: Kyle Bradish 6-9, 3.64 ERA
• Red Sox starting pitcher: Ranger Suarez 4-3, 3.19 ERA

Orioles vs. Red Sox Odds, Run Line, Over/Under & Moneyline

Orioles vs Red Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Tuesday‘s MLB game with 56.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Orioles vs Red Sox and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Orioles players for Tuesday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

• Taylor Ward has hit the Walks Over in 9 of his last 10 games (+9.30 Units / 90% ROI)
• Kyle Bradish has hit the Walks Allowed Over in 17 of his last 25 games (+9.20 Units / 27% ROI)
• Jeremiah Jackson has hit the Hits Over in 16 of his last 20 away games (+9.15 Units / 25% ROI)
• Jeremiah Jackson has hit the Singles Over in 14 of his last 20 away games (+9.06 Units / 44% ROI)
• Taylor Ward has hit the Runs Over in 16 of his last 25 away games (+8.80 Units / 34% ROI)

And here are some favorite MLB player prop bets for Red Sox players for Tuesday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Best Bets Today:

• Masataka Yoshida has hit the Home Runs Over in 3 of his last 9 games (+18.50 Units / 206% ROI)
• Jarren Duran has hit the Total Bases Under in 19 of his last 25 games (+13.75 Units / 43% ROI)
• Jarren Duran has hit the Hits Under in 16 of his last 25 games (+12.60 Units / 46% ROI)
• Ceddanne Rafaela has hit the Hits Runs and RBIs Over in 13 of his last 15 games (+10.55 Units / 54% ROI)
• Tsung-Che Cheng has hit the Runs Over in 6 of his last 9 games (+8.00 Units / 89% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have covered the Run Line in 29 of their last 50 games (+8.90 Units / 14% ROI)
• The Baltimore Orioles have hit the Moneyline in 7 of their last 8 games (+6.05 Units / 60% ROI)
• The Baltimore Orioles have hit the Game Total Under in 10 of their last 14 games (+5.80 Units / 38% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 10 of their last 17 away games (+5.60 Units / 29% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 23 of their last 40 games (+5.35 Units / 12% ROI)

Red Sox Best Bets Today:

• The Boston Red Sox have hit the Moneyline in 19 of their last 21 games (+16.80 Units / 64% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 19 of their last 23 games (+15.75 Units / 52% ROI)
• The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 19 of their last 23 games (+15.60 Units / 58% ROI)
• The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Over in 19 of their last 23 games (+15.25 Units / 55% ROI)
• The Boston Red Sox have covered the Run Line in 15 of their last 21 games (+13.70 Units / 54% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Red Sox vs Orioles Home Run Prop Bets Today

Red Sox vs Orioles Total Hits Prop Bets Today

Red Sox vs Orioles Strikeout Prop Bets Today

Orioles Keys to the Game vs. the Red Sox

The Orioles are just 3-7 (.300) when tied entering the 7th inning this season — 5th lowest in MLB; League Avg: .500.

The Orioles are just 2-4 (.333) when tied entering the 8th inning this season — tied for 4th lowest in MLB; League Avg: .500.

The Orioles are just 3-7 (.300) when tied entering the 7th inning since the 2025 season — 5th lowest in MLB; League Avg: .500.

The Orioles are just 2-4 (.333) when tied entering the 8th inning since the 2025 season — tied for 4th lowest in MLB; League Avg: .500.

Red Sox Keys to the Game vs. the Orioles

The Red Sox are just 2-7 (.222) when tied entering the 8th inning this season — lowest in MLB; League Avg: .500.

The Red Sox are just 1-43 (.023) when trailing entering the 9th inning this season — tied for 4th lowest in MLB; League Avg: .053.

The Red Sox are just 22-27 (.449) at home this season — 5th lowest in MLB; League Avg: .524.

The Red Sox are 47-1 (.979) when leading entering the 8th inning this season — tied for best in MLB; League Avg: .902.

Orioles Hitting Stats & Trends

The Orioles are batting just .150 with two-strikes this season — lowest in MLB.

Orioles hitters are slugging just .179 on pitches out of the zone this season — 2nd lowest in MLB.

Orioles hitters are slugging just .232 with two-strikes this season — tied for 2nd lowest in MLB.

Orioles hitters are averaging 3.98 pitches per plate appearance this season — tied for highest in MLB.

Red Sox Hitting Stats & Trends

Red Sox hitters are slugging .437 against LHP this season — 3rd best in MLB.

Red Sox hitters have an OPS of just .685 (2,706 PA’s) against RHP this season — 4th lowest in MLB.

Red Sox hitters have an OBP of .338 (1,003 PA’s) against LHP this season — 3rd best in MLB.

Red Sox hitters have struck out in just 20% of their PA’s against LHP this season — 4th best in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers have an ERA of 5.38 (236.0 IP) against division opponents this season — 3rd highest in MLB.

The Orioles pitchers have allowed their opponents to score first in 52% of their games on the road this season — 4th highest in MLB.

Orioles pitchers have allowed a run 35% of the time after their offense scores this season — 5th highest in MLB.

Orioles pitchers are throwing just 3.82 pitches per plate appearance this season — 5th lowest in MLB.

Red Sox Pitching Stats & Trends

Red Sox pitchers have a strikeout rate of 45% with two-strikes this season — 3rd best in MLB.

Red Sox pitchers have walked 7% of batters when facing the leadoff batter in the inning this season — 5th best in MLB.

Red Sox pitchers have allowed a run just 23% of the time after their offense scores this season — lowest in MLB.

The Red Sox have allowed 3.56 runs per game (178/50) on the road this season — 3rd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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