• The Cubs are -150 favorites vs the Padres
• Padres vs Cubs Over / Under today: 11.5 Runs
• Padres / Cubs TV Channel: MARQ | PDTV

The San Diego Padres (+125) visit Wrigley Field to take on the Chicago Cubs (-150) on June 29, 2026. First pitch is scheduled for 8:05 pm in Chicago, IL.

This season, the Padres are 43-39 against the spread (ATS), while the Cubs are 34-49 ATS.

Padres vs Cubs Starting Pitchers Today:

• Padres starting pitcher: Wandy Peralta 1-0, 1.69 ERA
• Cubs starting pitcher: Shota Imanaga 5-6, 4.41 ERA

Padres vs. Cubs Odds, Run Line, Over/Under & Moneyline

Padres vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Monday‘s MLB game with 57.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Padres vs Cubs and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Padres players for Monday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

• Freddy Fermin has hit the Home Runs Over in 3 of his last 8 games (+28.00 Units / 350% ROI)
• Freddy Fermin has hit the Hits Runs and RBIs Under in 20 of his last 25 games (+16.10 Units / 53% ROI)
• Freddy Fermin has hit the Hits Under in 19 of his last 25 games (+15.30 Units / 58% ROI)
• Freddy Fermin has hit the Singles Under in 21 of his last 25 games (+15.30 Units / 41% ROI)
• Freddy Fermin has hit the Total Bases Under in 19 of his last 25 games (+15.15 Units / 58% ROI)

And here are some favorite MLB player prop bets for Cubs players for Monday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

• Pete Crow-Armstrong has hit the Home Runs Over in 7 of his last 10 games at home (+23.50 Units / 235% ROI)
• Nico Hoerner has hit the Hits Under in 19 of his last 25 games at home (+15.10 Units / 34% ROI)
• Michael Busch has hit the Runs Under in 17 of his last 20 games at home (+12.65 Units / 41% ROI)
• Pete Crow-Armstrong has hit the RBIs Over in 8 of his last 10 games at home (+10.15 Units / 101% ROI)
• Pete Crow-Armstrong has hit the Total Bases Over in 17 of his last 25 games at home (+9.75 Units / 34% ROI)

Padres Best Bets Today:

• The San Diego Padres have hit the Game Total Under in 26 of their last 45 away games (+6.20 Units / 13% ROI)
• The San Diego Padres have hit the Team Total Under in 26 of their last 45 away games (+4.05 Units / 8% ROI)
• The San Diego Padres have covered the Run Line in 6 of their last 8 games (+3.55 Units / 29% ROI)
• The San Diego Padres have hit the Moneyline in 21 of their last 40 away games (+2.85 Units / 6% ROI)
• The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 35 away games (+2.60 Units / 6% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Under in 28 of their last 45 games (+10.50 Units / 20% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 10 of their last 17 games (+7.50 Units / 33% ROI)
• The Chicago Cubs have hit the Moneyline in 12 of their last 16 games (+7.40 Units / 35% ROI)
• The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 12 of their last 17 games (+6.80 Units / 34% ROI)
• The Chicago Cubs have hit the Team Total Under in 12 of their last 17 games at home (+6.55 Units / 33% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 43-37 against the Run Line (+0.15 Units / 0.13% ROI).

• 43-39 when betting on the Moneyline for +1.35 Units / 1.39% ROI
• 36-44 when betting on the total runs Over for -12.35 Units / -13.63% ROI
• 44-36 when betting on the total runs Under for +4.7 Units / 5.23% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 34-49 against the Run Line (-15.8 Units / -15.95% ROI).

• 46-38 when betting on the Moneyline for -1.95 Units / -1.72% ROI
• 45-38 when betting on the total runs Over for +3.7 Units / 3.99% ROI
• 38-45 when betting on the total runs Under for -10.9 Units / -11.82% ROI

Cubs vs Padres Home Run Prop Bets Today

Cubs vs Padres Total Hits Prop Bets Today

Cubs vs Padres Strikeout Prop Bets Today

Padres Keys to the Game vs. the Cubs

The Padres are 9-3 (.750) when tied entering the 7th inning this season — tied for 2nd best in MLB; League Avg: .500.

The Padres are 33-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB; League Avg: .943.

The Padres are 32-1 (.970) when leading entering the 8th inning this season — 5th best in MLB; League Avg: .896.

The Padres are 28-2 (.933) when scoring 5 or more runs this season — 2nd best in MLB; League Avg: .789.

Cubs Keys to the Game vs. the Padres

The Cubs are 23-2 (.920) when they’ve had 10 or more hits this season — 2nd best in MLB; League Avg: .753.

The Cubs are 35-3 (.921) when leading entering the 7th inning this season — 5th best in MLB; League Avg: .858.

The Cubs are 4-36 (.100) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .057.

The Cubs are 12-4 (.750) when they’ve scored in the first inning this season — tied for 3rd best in MLB; League Avg: .640.

Padres Hitting Stats & Trends

Padres hitters have an OPS of just .662 (3,003 PA’s) this season — lowest in MLB.

Padres hitters have an OPS of just .626 (1,734 PA’s) against starting pitchers this season — lowest in MLB.

The Padres are batting just .208 against starting pitchers this season — lowest in MLB.

Padres hitters are slugging just .365 this season — 2nd lowest in MLB.

Cubs Hitting Stats & Trends

Cubs hitters have an OBP of .331 (2,396 PA’s) against RHP this season — 5th best in MLB.

Cubs hitters have drawn walks in 11% of their PA’s against RHP this season — best in MLB.

Cubs hitters have an OBP of .350 (1,571 PA’s) at home this season — tied for 2nd best in MLB.

Cubs hitters have an OBP of .372 (325 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Padres Pitching Stats & Trends

Opponents have a groundball rate of 46% against Padres pitchers this season — tied for 3rd highest in MLB.

Padres pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

The Padres have allowed 1.05 runs per game (86/82) in late innings this season — 4th best in MLB.

Opponents have a groundball batting average of .279 against Padres pitchers with runners on base this season — 4th highest in MLB.

Cubs Pitching Stats & Trends

Opponents have a groundball batting average of just .202 against Cubs pitchers with runners on base this season — best in MLB.

Cubs pitchers have picked-off 14 runners from first base this season — most in MLB.

Cubs pitchers have allowed an exit velocity over 105 MPH 219 times this season — 5th most in MLB.

Cubs pitchers have allowed an exit velocity of 95 MPH or greater 902 times this season — 4th most in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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