Padres vs Diamondbacks Prediction, Odds & Player Prop Bets Today – MLB, Apr 21

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Apr 21, 2023, 3:31 PM
  • The Padres are -115 favorites vs the Diamondbacks
  • Padres starting pitcher: Jacob Lugo
  • Diamondbacks starting pitcher: Zachary Gallen
  • Watch the game on MLB Network

The San Diego Padres (-115) visit Chase Field to take on the Arizona Diamondbacks (-105) on Friday, April 21, 2023. First pitch is scheduled for 9:40pm EDT in Phoenix.

The Padres are the betting favorite in this game, with the run line sitting at -1.5 (+140).

The Padres vs Diamondbacks Over/Under is 9.5 total runs for the game.

This season, the Padres are 10-11 against the spread (ATS), while the Diamondbacks are 13-7 ATS.

Padres vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres-1.5 +140O 9.5 -120-115
Diamondbacks +1.5 -165U 9.5 +100-105

Padres vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Friday‘s MLB matchup with 51.9% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Padres and Diamondbacks and up-to-date player injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Friday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Xander Bogaerts has hit the Hits Over in 20 of his last 22 games (+18.80 Units / 41% ROI)
  • Manny Machado has hit the Runs Under in 18 of his last 22 games (+12.85 Units / 35% ROI)
  • Xander Bogaerts has hit the Singles Over in 13 of his last 14 games (+12.10 Units / 72% ROI)
  • Austin Nola has hit the Hits Runs and RBIs Under in his last 10 away games (+11.40 Units / 94% ROI)
  • Juan Soto has hit the Hits Under in 13 of his last 21 games (+9.80 Units / 47% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Friday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

  • Christian Walker has hit the RBIs Over in 8 of his last 11 games (+9.30 Units / 85% ROI)
  • Pavin Smith has hit the RBIs Over in his last 5 games (+9.00 Units / 180% ROI)
  • Alek Thomas has hit the Hits Under in 12 of his last 17 games (+8.90 Units / 47% ROI)
  • Alek Thomas has hit the Singles Under in 13 of his last 17 games (+8.10 Units / 36% ROI)
  • Christian Walker has hit the Hits Under in 9 of his last 15 games (+7.35 Units / 49% ROI)

Diamondbacks vs Padres Home Run Prop Bets Today

Over Under
Josh Rojas 0.5 +750 0.5 -3000
Christian Walker 0.5 +525 0.5 -1200
Austin Nola 0.5 +875 0.5 -5000
Corbin Carroll 0.5 +525 0.5 -1200
Geraldo Perdomo 0.5 +1200 0.5

Diamondbacks vs Padres Total Hits Prop Bets Today

Over Under
Josh Rojas 0.5 -275 0.5 +195
Christian Walker 0.5 -225 0.5 +175
Austin Nola 0.5 -155 0.5 +120
Corbin Carroll 0.5 -250 0.5 +175
Geraldo Perdomo 0.5 +100 0.5 -130

Diamondbacks vs Padres RBI Prop Bets Today

Over Under
Josh Rojas 0.5 +210 0.5 -300
Christian Walker 0.5 +130 0.5 -175
Austin Nola 0.5 +270 0.5 -375
Corbin Carroll 0.5 +170 0.5 -225
Geraldo Perdomo 0.5 +310 0.5 -450

Diamondbacks vs Padres Strikeout Prop Bets Today

Over Under
Zac Gallen 6.5 +115 6.5 -150
Seth Lugo 4.5 +110 4.5 -140
  • The San Diego Padres have hit the Team Total Under in 9 of their last 11 games (+7.00 Units / 55% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 9 of their last 11 games (+6.90 Units / 51% ROI)
  • The San Diego Padres have hit the Moneyline in 5 of their last 7 away games (+3.55 Units / 47% ROI)
  • The San Diego Padres have hit the Game Total Under in 9 of their last 14 games (+3.30 Units / 21% ROI)
  • The San Diego Padres have covered the Run Line in 6 of their last 8 away games (+2.35 Units / 18% ROI)
  • The Arizona Diamondbacks have covered the 1st Five Innings (F5) Run Line in 10 of their last 12 games (+7.95 Units / 55% ROI)
  • The Arizona Diamondbacks have hit the Moneyline in 11 of their last 19 games (+7.15 Units / 36% ROI)
  • The Arizona Diamondbacks have covered the Run Line in 12 of their last 17 games (+6.55 Units / 28% ROI)
  • The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 7 of their last 12 games (+5.85 Units / 45% ROI)
  • The Arizona Diamondbacks have hit the Team Total Over in their last 5 games (+5.30 Units / 97% ROI)

Padres Against the Spread (ATS) Record

Against the spread this MLB season, the Padres have gone 10-11 against the Run Line (-3.05 Units / -10.89% ROI).

  • 10-11 when betting on the Moneyline for -5.1 Units / -17.29% ROI
  • 10-11 when betting on the total runs Over for -2.15 Units / -9.25% ROI
  • 11-10 when betting on the total runs Under for +0.05 Units / 0.22% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this MLB season, the Diamondbacks have gone 13-7 against the Run Line (+5.05 Units / 18.43% ROI).

  • 11-9 when betting on the Moneyline for +6.15 Units / 29.43% ROI
  • 11-8 when betting on the total runs Over for +2.2 Units / 9.93% ROI
  • 8-11 when betting on the total runs Under for -3.9 Units / -17.77% ROI

Right-handed hitters have a miss rate of just 20% (71/346) against Seth Lugo since last season — 6th lowest among qualified RPs in MLB*; League Avg: 29% — sixth Percentile.

8 of Seth Lugo’s 35 breaking pitch strikeouts (23%) have been backdoor since last season — 7th highest among qualified RPs in MLB*; League Avg: 11% — 93rd Percentile.

Seth Lugo has thrown his curveball 41% of the time (83/201) in non-two strike counts this season — 2nd highest in MLB among starting pitchers with at least 6 total CB; League Avg: 16% — 98th Percentile.

Right-handed batters are hitting .272 (49-for-180) against Seth Lugo since last season — tied for 14th highest among among 104 qualified RPs in MLB*; League Avg: .229 — 14th Percentile.

Diamondbacks Starting Pitcher Stats & Trends

Zac Gallen has allowed an OBP of just .067 (30 PA’s) with two-strikes — 3rd best in MLB over the last two weeks; League Avg: .248 — 97th Percentile.

Zac Gallen has a strikeout rate of just 6% (1 SO in 17 PAs) in PAs ending on elevated fastballs this season — 2nd lowest among qualified SPs in MLB; League Avg: 25% — third Percentile.

Left-handed batters are hitting just .147 (51-for-347) against Zac Gallen since last season — best in MLB among starting pitchers with at least 71 total IP; League Avg: .235 — 100th Percentile.

Zac Gallen has allowed an OBP of just .217 (378 PA’s) vs left-handed batters since last season — 2nd best in MLB among starting pitchers with at least 71 total IP; League Avg: .304 — 98th Percentile.

Padres Keys to the Game vs. the Diamondbacks

The Padres are 19-21 (.475) when moneyline underdogs of less than +150 since the 2022 season — 8th best in MLB; League Avg: .418.

The Padres are 49-39 (.557) on the road since the 2022 season — 6th best in MLB; League Avg: .473.

The Padres are just 8-151 (.050) when trailing entering the 8th inning since the 2020 season — 3rd lowest in MLB; League Avg: .086.

The Padres are 82-29 (.739) when allowing 4 or fewer runs since the 2022 season — 9th best in MLB; League Avg: .707.

Diamondbacks Keys to the Game vs. the Padres

The Diamondbacks are just 122-24 (.836) when leading entering the 8th inning since the 2020 season — lowest in MLB; League Avg: .914.

The Diamondbacks are just 111-36 (.755) when leading entering the 7th inning since the 2020 season — lowest in MLB; League Avg: .875.

The Diamondbacks are just 65-12 (.844) when leading entering the 8th inning since the 2022 season — lowest in MLB; League Avg: .915.

The Diamondbacks are just 109-23 (.826) when leading entering the 8th inning since the 2021 season — lowest in MLB; League Avg: .910.

Padres hitters have an OBP of just .258 (90 PA’s) when facing the starting pitcher for the 3rd time in a game this season — tied for 4th lowest in MLB; League Avg: .330.

The Padres are batting just .223 on the road this season — 4th lowest in MLB; League Avg: .248.

Padres hitters have just 793 strikeouts in 3,812 PA’s (21%) against LHP since the 2021 season — 5th best in MLB; League Avg: 23%.

The Padres are batting just .229 at home since last season — tied for 3rd lowest in MLB; League Avg: .246.

Diamondbacks hitters have an OPS of just .666 (1,942 PA’s) against LHP since last season — 4th lowest in MLB; League Avg: .716.

Diamondbacks hitters have drawn 26 walks in 477 PA’s (6%) against RHP this season — lowest in MLB; League Avg: 9%.

Diamondbacks hitters have an OBP of just .296 (1,942 PA’s) against LHP since last season — tied for 4th lowest in MLB; League Avg: .316.

Diamondbacks hitters have an OBP of just .299 (825 PA’s) when facing the starting pitcher for the 3rd time in a game since last season — tied for 2nd lowest in MLB; League Avg: .326.

Padres pitchers have walked 21 of 125 batters (17%) when facing the leadoff batter in the inning over the last 14 days (14 games) — highest in MLB; League Avg: 9%.

Padres pitchers have walked 11 of 63 batters (17%) when facing the leadoff batter in the inning over the past seven days (7 games) — highest in MLB; League Avg: 9%.

Opponents have a groundball batting average of just .197 against Padres pitchers with the shift since the 2020 season — best in MLB; League Avg: .224.

Padres pitchers have walked 24 of 188 batters (13%) when facing the leadoff batter in the inning this season — highest in MLB; League Avg: 9%.

Diamondbacks pitchers have a strikeout rate of just 18% in close and late situations since last season — lowest in MLB; League Avg: 25%.

Opponents have a groundball rate of just 41% against Diamondbacks pitchers since last season — lowest in MLB; League Avg: 43%.

Diamondbacks pitchers have a strikeout rate of just 19% in close and late situations since the 2021 season — lowest in MLB; League Avg: 25%.

Opponents have a miss rate of just 23% against Diamondbacks pitchers since last season — 5th lowest in MLB; League Avg: 26%.

Diamondbacks vs. Padres Injuries Tonight That May Affect Prop Bets 

  • Joseph Mantiply (Diamondbacks): Shoulder, D15
  • Zachary Davies (Diamondbacks): Oblique, D15
  • Kyle Lewis (Diamondbacks): Illness, D10
  • Jose Herrera (Diamondbacks): Head, Day-to-Day
  • Mark Melancon (Diamondbacks): Shoulder, D60
  • Cole Sulser (Diamondbacks): Shoulder, D60
  • Corbin Martin (Diamondbacks): Lat, D60
  • Carson Kelly (Diamondbacks): Forearm, D10
  • Thomas Pomeranz (Padres): Elbow/Flexor, D15
  • José Castillo (Padres): Shoulder, D15
  • Adrian Morejon (Padres): Elbow, D60
  • Adam Engel (Padres): Hamstring, D10
  • David Dahl (Padres): Quad, D10
  • Robert Suarez (Padres): Elbow, D60
  • Nabil Crismatt (Padres): Hip Strain, D15
  • Eguy Rosario (Padres): Ankle, D60
  • Luis Campusano (Padres): Thumb Sprain, D10
  • Joseph Musgrove (Padres): Toe, D15

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.