Padres vs Giants Prediction, Odds & Player Prop Bets Today – MLB, Sep 27

min read
MLB betting odds, predictions and betting odds for today's games
(AP Photo)
BetMGM Betting @BETMGM Sep 27, 2023, 3:31 PM
  • The Padres are -110 favorites vs the Giants
  • Padres starting pitcher: Matthew Waldron
  • Giants starting pitcher: Sean Manaea
  • Watch the game on NBCS-BA

The San Diego Padres (-110) visit Oracle Park to take on the San Francisco Giants (-110) on Wednesday, September 27, 2023. First pitch is scheduled for 9:45pm EDT in San Francisco.

The Padres are the betting favorite in this game, with the run line sitting at -1.5 (+150).

The Padres vs Giants Over/Under is 8.5 total runs for the game.

This season, the Padres are 78-80 against the spread (ATS), while the Giants are 71-87 ATS.

Padres vs. Giants Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres-1.5 +150O 8.5 -115-110
Giants +1.5 -185U 8.5 -105-110

Padres vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB matchup with 51.0% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Padres and Giants and up-to-date player injuries.


Bet now on Padres vs Giants and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Blake Snell has hit the Earned Runs Under in 21 of his last 26 games (+15.80 Units / 46% ROI)
  • Xander Bogaerts has hit the Total Bases Over in 17 of his last 22 games (+14.50 Units / 50% ROI)
  • Xander Bogaerts has hit the Hits Runs and RBIs Over in 18 of his last 22 games (+13.65 Units / 50% ROI)
  • Xander Bogaerts has hit the Hits Over in 17 of his last 22 games (+12.70 Units / 31% ROI)
  • Blake Snell has hit the Pitching Outs Over in 20 of his last 27 games (+12.35 Units / 38% ROI)

And here are some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

  • Logan Webb has hit the Pitching Outs Over in 23 of his last 31 games (+15.45 Units / 38% ROI)
  • Thairo Estrada has hit the Hits Over in 26 of his last 40 games (+11.10 Units / 15% ROI)
  • Paul DeJong has hit the Hits Runs and RBIs Under in 14 of his last 17 games at home (+10.90 Units / 43% ROI)
  • Paul DeJong has hit the Total Bases Under in 13 of his last 16 games at home (+10.70 Units / 62% ROI)
  • Paul DeJong has hit the Hits Under in 13 of his last 16 games at home (+10.60 Units / 60% ROI)

Giants vs Padres Home Run Prop Bets Today

Over Under
Jurickson Profar 0.5 +800 0.5 -3000
Mike Yastrzemski 0.5 +375 0.5 -700
LaMonte Wade Jr 0.5 +500 0.5 -1100
Joc Pederson 0.5 +320 0.5 -550
Ha-seong Kim 0.5 +750 0.5 -3000

Giants vs Padres Total Hits Prop Bets Today

Over Under
Jurickson Profar 0.5 -210 0.5 +160
Mike Yastrzemski 0.5 -225 0.5 +165
LaMonte Wade Jr 0.5 -225 0.5 +170
Joc Pederson 0.5 -250 0.5 +180
Ha-seong Kim 0.5 -250 0.5 +180

Giants vs Padres RBI Prop Bets Today

Over Under
Jurickson Profar 0.5 +195 0.5 -275
Mike Yastrzemski 0.5 +165 0.5 -225
LaMonte Wade Jr 0.5 +200 0.5 -275
Joc Pederson 0.5 +125 0.5 -160
Ha-seong Kim 0.5 +155 0.5 -210

Giants vs Padres Strikeout Prop Bets Today

Over Under
Matt Waldron 3.5 -105 3.5 -125
Sean Manaea 3.5 -150 3.5 +110
  • The San Diego Padres have hit the Game Total Under in 80 of their last 151 games (+13.70 Units / 8% ROI)
  • The San Diego Padres have hit the Moneyline in 16 of their last 23 games (+8.45 Units / 24% ROI)
  • The San Diego Padres have hit the Team Total Under in 42 of their last 73 away games (+8.15 Units / 10% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 10 of their last 12 games (+7.80 Units / 37% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 10 of their last 12 games (+7.62 Units / 51% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 70 of their last 111 games (+25.02 Units / 19% ROI)
  • The San Francisco Giants have hit the Game Total Under in 82 of their last 144 games (+18.10 Units / 12% ROI)
  • The San Francisco Giants have hit the Team Total Under in 51 of their last 81 games (+18.03 Units / 19% ROI)
  • The San Francisco Giants have hit the Moneyline in 27 of their last 43 games at home (+7.00 Units / 11% ROI)
  • The San Francisco Giants have covered the Run Line in 35 of their last 69 games at home (+3.75 Units / 4% ROI)

Padres Against the Spread (ATS) Record

Against the spread this MLB season, the Padres have gone 79-79 against the Run Line (-5.45 Units / -2.84% ROI).

  • 78-80 when betting on the Moneyline for -30.75 Units / -13.09% ROI
  • 66-82 when betting on the total runs Over for -25.3 Units / -14.38% ROI
  • 82-66 when betting on the total runs Under for +10.45 Units / 6.07% ROI

Giants Against the Spread (ATS) Record

Against the spread this MLB season, the Giants have gone 71-87 against the Run Line (-26.75 Units / -13.08% ROI).

  • 78-80 when betting on the Moneyline for -16 Units / -7.8% ROI
  • 68-87 when betting on the total runs Over for -28.45 Units / -16.22% ROI
  • 87-68 when betting on the total runs Under for +13.25 Units / 7.69% ROI

Matt Waldron has allowed at least one HR in each of his last seven games dating back to June 24th — tied with Ben Lively for the longest active streak among active MLB players.

Matt Waldron had a first-pitch strike rate of just 41% (9/22) — 3rd lowest in MLB over the last week; League Avg: 63% — third Percentile.

Matt Waldron has a first-pitch strike rate of just 41% (9/22) over the past seven days (1 games) — 3rd lowest in NL over the last week; League Avg: 62% — sixth Percentile.

Opponents had a groundball rate of 64% (7/11) against Matt Waldron — 7th highest in MLB over the last week; League Avg: 44% — 94th Percentile.

Giants Starting Pitcher Stats & Trends

Sean Manaea has allowed a slugging percentage of .765 (26 Total Bases / 34 ABs) on low fastballs this season — 2nd highest among in MLB; League Avg: .413 — second Percentile.

Sean Manaea has allowed an OBP of just .130 (23 PA’s) over the past seven days (1 games) — best in NL over the last week; League Avg: .302 — 100th Percentile.

Opponents are hitting .320 (8-for-25) against Sean Manaea with two-strikes — highest in MLB over the last two weeks; League Avg: .160 — first Percentile.

Sean Manaea has allowed a slugging percentage of .765 (26 Total Bases / 34 ABs) on low fastballs this season — 3rd highest among qualified RPs in MLB*; League Avg: .409 — second Percentile.

Padres Keys to the Game vs. the Giants

The Padres are just 2-13 (.133) after a win as underdogs this season — lowest in MLB; League Avg: .438.

The Padres are just 9-34 (.209) when allowing 2 or more home runs this season — 4th lowest in MLB; League Avg: .311.

The Padres are just 3-63 (.045) when trailing entering the 8th inning this season — 4th lowest in MLB; League Avg: .100.

The Padres are just 14-28 (.333) after a win as underdogs since last season — 2nd lowest in MLB; League Avg: .419.

Giants Keys to the Game vs. the Padres

The Giants are 129-3 (.977) when leading entering the 9th inning since last season — 3rd best in MLB; League Avg: .951.

The Giants are just 23-43 (.348) after a loss as underdogs since last season — 4th lowest in MLB; League Avg: .405.

The Giants are 64-1 (.985) when leading entering the 9th inning this season — 2nd best in MLB; League Avg: .948.

The Giants are 20-11 (.645) after a home loss this season — 4th best in MLB; League Avg: .505.

The Padres are just 2-13 (.133) after a win as underdogs this season — lowest in MLB; League Avg: .438.

Padres hitters have drawn 892 walks in 8,707 PA’s (10%) against RHP since last season — best in MLB; League Avg: 8%.

Padres hitters have drawn 478 walks in 4,359 PA’s (11%) against RHP this season — best in MLB; League Avg: 9%.

Padres hitters have chased 26% of pitches out of the zone against RHP this season — 2nd lowest in MLB; League Avg: 29%.

Giants hitters are slugging just .378 against LHP this season — 3rd lowest in MLB; League Avg: .418.

Giants hitters have 922 strikeouts in 3,687 PA’s (25%) against LHP since last season — 2nd highest in MLB; League Avg: 22%.

The Giants are batting just .240 when facing the starting pitcher for the 3rd time in a game since last season — lowest in MLB; League Avg: .266.

Giants hitters have an OPS of just .687 (1,755 PA’s) against LHP this season — 4th lowest in MLB; League Avg: .741.

Padres pitchers have allowed an average Exit Velocity of 88.0 MPH (3,753 batted balls) this season — best in MLB; League Avg: 89.0.

Opponents have a groundball rate of 45% against Padres pitchers this season — 3rd highest in MLB; League Avg: 43%.

The Padres have allowed 3.74 runs per game (303/81) at home this season — best in MLB; League Avg: 4.65.

Padres pitchers have allowed opponents to score in three different innings in 39% of their games this season — 2nd lowest in MLB; League Avg: 49%.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 50% against Giants pitchers this season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 48% against Giants pitchers since the 2021 season — highest in MLB; League Avg: 43%.

Giants pitchers have walked 397 of 5,890 batters (7%) this season — best in MLB; League Avg: 9%.

Giants vs. Padres Injuries Tonight That May Affect Prop Bets 

  • Keaton Winn (Giants): COVID-19, D10
  • Roberto Pérez (Giants): Shoulder, D60
  • Mark Mathias (Giants): Shoulder, D60
  • Jakob Junis (Giants): Cervical strain, D15
  • Jonathan Davis (Giants): Shoulder, Day-to-Day
  • Brandon Crawford (Giants): Hamstring, D10
  • Alexander Cobb (Giants): Hip, D15
  • Thomas Szapucki (Giants): Arm, D60
  • Cole Waites (Giants): Elbow, D60
  • Scott Alexander (Giants): Hamstring, D15
  • Kyle Harrison (Giants): Illness, Day-to-Day
  • Anthony DeSclafani (Giants): Elbow, D60
  • Thomas Pomeranz (Padres): Elbow/Flexor, D60
  • Timothy Hill (Padres): Finger, D60
  • Steven Wilson (Padres): Hip, D15
  • Jacob Cronenworth (Padres): Wrist, D10
  • Alek Jacob (Padres): Elbow, D60
  • Drew Carlton (Padres): Elbow, D60
  • Gary Sánchez (Padres): Wrist, D60
  • Matthew Carpenter (Padres): Elbow, D10
  • Joseph Musgrove (Padres): Shoulder, D15
  • Yu Darvish (Padres): Elbow, D15
  • David Knehr (Padres): Elbow, D60

Bet now on Padres vs Giants and all games with BetMGM


Bet on MLB Odds at BetMGM

At BetMGM, you can bet online with updated MLB betting odds. And with live sports betting, the best online sports betting and mobile sports betting (with the BetMGM Sportsbook app) experiences are at BetMGM.

BetMGM First Bet Offer $1,500
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.