- The Padres are +105 favorites vs the Guardians
- Padres vs Guardians Over / Under today: 8 Runs
- Padres / Guardians TV Channel: GDTV | PDTV | KFMB
The San Diego Padres (+105) visit Progressive Field to take on the Cleveland Guardians (-125) on August 15, 2026. First pitch is scheduled for 7:10 pm in Cleveland, OH.
This season, the Padres are 66-57 against the spread (ATS), while the Guardians are 57-65 ATS.
Padres vs Guardians Starting Pitchers Today:
- Padres starting pitcher: Randy Vasquez 8-6, 4.18 ERA
- Guardians starting pitcher: Joey Cantillo 8-7, 3.93 ERA
Padres vs. Guardians Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Padres | -1.5 +165 | O 8 +100 | +105 |
| Guardians | +1.5 -220 | U 8 -120 | -125 |
Padres vs Guardians Prediction for Today’s Game
Based on recent trends the model predicts the Guardians will win Saturday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Padres players for Saturday‘s game, looking at profitable historical betting trends:
Best Padres Player Prop Bets Today:
- Fernando Tatis Jr. has hit the Home Runs Over in 5 of his last 8 games (+19.00 Units / 238% ROI)
- Jackson Merrill has hit the Runs Over in 17 of his last 25 games (+13.90 Units / 55% ROI)
- Ty France has hit the Hits Runs and RBIs Over in 19 of his last 25 games (+12.50 Units / 41% ROI)
- Ty France has hit the Hits Over in 20 of his last 25 games (+11.30 Units / 22% ROI)
- Ty France has hit the Total Bases Over in 16 of his last 25 games (+11.00 Units / 39% ROI)
And here are some favorite MLB player prop bets for Guardians players for Saturday‘s game, looking at profitable historical betting trends:
Best Guardians Player Prop Best Bets Today:
- Patrick Bailey has hit the Home Runs Over in 3 of his last 7 games at home (+20.00 Units / 286% ROI)
- Steven Kwan has hit the Hits Over in 19 of his last 20 games at home (+17.15 Units / 43% ROI)
- Steven Kwan has hit the Singles Over in 17 of his last 20 games at home (+13.25 Units / 52% ROI)
- Brayan Rocchio has hit the Hits Runs and RBIs Under in 17 of his last 20 games (+13.20 Units / 47% ROI)
- Brayan Rocchio has hit the Runs Under in 18 of his last 20 games (+13.10 Units / 30% ROI)
Padres Best Bets Today:
- The San Diego Padres have hit the Moneyline in 16 of their last 20 games (+11.25 Units / 44% ROI)
- The San Diego Padres have hit the Team Total Over in 28 of their last 45 away games (+9.75 Units / 19% ROI)
- The San Diego Padres have covered the Run Line in 21 of their last 35 games (+8.25 Units / 19% ROI)
- The San Diego Padres have hit the 1st Five Innings (F5) Team Total Over in 15 of their last 23 games (+7.45 Units / 30% ROI)
- The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 9 of their last 14 games (+3.60 Units / 22% ROI)
Guardians Best Bets Today:
- The Cleveland Guardians have hit the Game Total Over in 8 of their last 10 games (+5.80 Units / 53% ROI)
- The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 26 of their last 45 games (+5.80 Units / 11% ROI)
- The Cleveland Guardians have hit the Team Total Over in 8 of their last 11 games at home (+4.60 Units / 38% ROI)
Padres Against the Spread (ATS) Record
Against the spread this season, the Padres are 66-55 against the Run Line (+5.1 Units / 3.11% ROI).
- 66-57 when betting on the Moneyline for +5.55 Units / 3.82% ROI
- 56-64 when betting on the total runs Over for -14.45 Units / -10.64% ROI
- 64-56 when betting on the total runs Under for +2.75 Units / 2.04% ROI
Guardians Against the Spread (ATS) Record
Against the spread this season, the Guardians are 57-65 against the Run Line (-12.15 Units / -7.67% ROI).
- 59-64 when betting on the Moneyline for -10.5 Units / -7.11% ROI
- 60-63 when betting on the total runs Over for -8.8 Units / -6.55% ROI
- 63-60 when betting on the total runs Under for -3.7 Units / -2.71% ROI
Padres Keys to the Game vs. the Guardians
The Padres are 7-2 (.778) when allowing 5 or more extra base hits this season — tied for 2nd best in MLB.
The Padres are 7-2 (.778) this season — tied for 2nd best in MLB.
The Padres are 7-2 (.778) since the 2025 season — tied for 2nd best in MLB.
The Padres are 7-2 (.778) when allowing 5 or more extra base hits since the 2025 season — tied for 2nd best in MLB.
Guardians Keys to the Game vs. the Padres
The Guardians are just 2-7 (.222) this season — tied for lowest in MLB.
The Guardians are just 2-5 (.286) when allowing 5 or more extra base hits this season — 3rd lowest in MLB.
The Guardians are just 2-7 (.222) since the 2025 season — tied for lowest in MLB.
The Guardians are just 2-5 (.286) when allowing 5 or more extra base hits since the 2025 season — 3rd lowest in MLB.
Padres Hitting Stats & Trends
The Padres are batting .252 with two outs this season — 3rd best in MLB.
The Padres have answered-back in 37% of innings after an opponent scores in late innings this season — highest in MLB.
The Padres are batting .369 on the first pitch of at-bats this season — 2nd best in MLB.
Padres hitters have an OPS of .754 (1,476 PA’s) in innings 7-9 this season — 4th best in MLB.
Guardians Hitting Stats & Trends
Guardians hitters are slugging just .344 against LHP this season — tied for 2nd lowest in MLB.
Guardians hitters have an OPS of just .540 (318 PA’s) against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB.
The Guardians are batting just .218 on the road this season — lowest in MLB.
The Guardians are batting just .226 against LHP this season — 3rd lowest in MLB.
Padres Pitching Stats & Trends
Opponents have a groundball rate of 45% against Padres pitchers this season — tied for 5th highest in MLB.
Padres pitchers have a strikeout rate of 28% in close and late situations this season — 2nd best in MLB.
The Padres pitchers have allowed their opponents to score first in 62% of their games at home this season — 5th highest in MLB.
The longest HR allowed by the Padres pitchers this season traveled 0.0 feet — — tied for shortest in MLB
Guardians Pitching Stats & Trends
Opponents have a miss rate of 27% against Guardians pitchers this season — 4th best in MLB.
Guardians pitchers have a strikeout rate of 25% this season — 3rd best in MLB.
Guardians pitchers have induced opposing hitters to ground into just 63 double plays in 871 opportunities (7%) this season — 2nd lowest in MLB.
Guardians pitchers have a strikeout rate of 27% in late innings this season — best in MLB.
More MLB Reading:
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