Padres vs Reds Prediction, Odds & Player Prop Bets Today – MLB, Jun 28

Cincinnati Reds' Blake Dunn rounds the bases to score on a base hit by Matt McLain during the third inning of a spring training baseball game against the Los Angeles Angels, Tuesday, March 18, 2025, in Goodyear, Ariz. (AP Photo/Matt York)
  • The Reds are -160 favorites vs the Padres
  • Padres vs Reds Over / Under today: 9.5 Runs
  • Padres / Reds TV Channel: FDOH | PDTV

The San Diego Padres (+135) visit Great American Ball Park to take on the Cincinnati Reds (-160) on Saturday, June 28, 2025. First pitch is scheduled for 4:10pm EDT in Cincinnati, OH.

This season, the Padres are 44-37 against the spread (ATS), while the Reds are 45-36 ATS.

Padres vs Reds Starting Pitchers Today:

  • Padres starting pitcher: Randy Vasquez 3-4, 3.65 ERA
  • Reds starting pitcher: Andrew Abbott 7-1, 1.79 ERA

Padres vs. Reds Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres+1.5 -160O 9.5 -115+135
Reds -1.5 +135U 9.5 -105-160

Padres vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Saturday‘s MLB game with 57.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Saturday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Fernando Tatis Jr. has hit the RBIs Under in 18 of his last 20 away games (+13.05 Units / 28% ROI)
  • Fernando Tatis Jr. has hit the Hits Under in 19 of his last 25 games (+12.70 Units / 27% ROI)
  • Luis Arraez has hit the Singles Under in 12 of his last 20 away games (+11.05 Units / 55% ROI)
  • Fernando Tatis Jr. has hit the Total Bases Under in 18 of his last 25 games (+9.05 Units / 28% ROI)
  • Randy Vasquez has hit the Strikeouts Under in 12 of his last 15 away games (+8.80 Units / 44% ROI)

And here are some favorite MLB player prop bets for Reds players for Saturday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

  • Elly De La Cruz has hit the Runs Over in 17 of his last 25 games (+10.35 Units / 39% ROI)
  • Matt McLain has hit the Singles Over in 15 of his last 25 games at home (+10.00 Units / 40% ROI)
  • Elly De La Cruz has hit the Total Bases Over in 16 of his last 25 games (+9.30 Units / 34% ROI)
  • Gavin Lux has hit the Home Runs Over in 2 of his last 4 games at home (+9.00 Units / 225% ROI)
  • Elly De La Cruz has hit the Walks Under in his last 9 games (+9.00 Units / 43% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 26 of their last 39 games (+12.10 Units / 26% ROI)
  • The San Diego Padres have hit the Game Total Under in 39 of their last 67 games (+10.40 Units / 14% ROI)
  • The San Diego Padres have hit the Team Total Under in 25 of their last 38 away games (+10.30 Units / 23% ROI)
  • The San Diego Padres have covered the Run Line in 10 of their last 16 away games (+2.70 Units / 12% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 11 of their last 20 games (+1.60 Units / 7% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 36 of their last 59 games (+11.75 Units / 18% ROI)
  • The Cincinnati Reds have hit the Moneyline in 13 of their last 19 games (+8.75 Units / 43% ROI)
  • The Cincinnati Reds have covered the Run Line in 13 of their last 20 games at home (+7.15 Units / 27% ROI)
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 40 of their last 72 games (+4.80 Units / 6% ROI)
  • The Cincinnati Reds have hit the Team Total Over in 9 of their last 13 games (+4.45 Units / 29% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 42-39 against the Run Line (-1.25 Units / -1.19% ROI).

  • 44-37 when betting on the Moneyline for +0.95 Units / 0.88% ROI
  • 33-45 when betting on the total runs Over for -16.05 Units / -18.09% ROI
  • 45-33 when betting on the total runs Under for +8.55 Units / 9.53% ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 45-36 against the Run Line (+2.4 Units / 2.15% ROI).

  • 43-39 when betting on the Moneyline for +1.75 Units / 1.8% ROI
  • 34-46 when betting on the total runs Over for -15.85 Units / -17.7% ROI
  • 46-34 when betting on the total runs Under for +8.7 Units / 9.58% ROI

Reds vs Padres Home Run Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +230 0.5 -285
Elly De La Cruz (CIN) 0.5 +300 0.5 -375
Fernando Tatis Jr. (SD) 0.5 +310 0.5 -400
Jackson Merrill (SD) 0.5 +340 0.5 -450
Will Benson (CIN) 0.5 +350 0.5 -450

Reds vs Padres Total Hits Prop Bets Today

Over Under
Tyler Stephenson (CIN) 0.5 -250 0.5 +185
Fernando Tatis Jr. (SD) 0.5 -250 0.5 +195
TJ Friedl (CIN) 0.5 -235 0.5 +180
Xander Bogaerts (SD) 0.5 -220 0.5 +165
Jose Trevino (CIN) 0.5 -210 0.5 +160

Reds vs Padres RBI Prop Bets Today

Over Under
Elly De La Cruz (CIN) 0.5 +110 0.5 -145
Austin Hays (CIN) 0.5 +110 0.5 -145
Jackson Merrill (SD) 0.5 +120 0.5 -160
Manny Machado (SD) 0.5 +130 0.5 -165
Tyler Stephenson (CIN) 0.5 +150 0.5 -200

Reds vs Padres Strikeout Prop Bets Today

Over Under
Andrew Abbott (CIN) 4.5 +115 4.5 -150
Randy Vasquez (SD) 3.5 +115 3.5 -155

Opponents are hitting just .091 (2-for-22) against Randy Vasquez’s low fastballs this season — 2nd best in MLB among starting pitchers with at least 32 total IP; League Avg: .279 — 99th Percentile.

Randy Vasquez has struck out just 10% (35/368) of left-handed batters he faced since last season — lowest in MLB among starting pitchers with at least 96 total IP; League Avg: 22% — 0 Percentile.

Randy Vasquez has a strikeout rate of just 29% (107 SO in 368 PAs) with two-strikes since last season — lowest in MLB among starting pitchers with at least 96 total IP; League Avg: 42% — 0 Percentile.

Randy Vasquez has thrown at least two strikes in his first three pitches to 51% (58/114) of right-handed hitters this season — lowest in MLB among starting pitchers with at least 32 total IP; League Avg: 65% — 0 Percentile.

Reds Starting Pitcher Stats & Trends

Andrew Abbott has walked 2% of batters this month (4 games) — 2nd best among qualified SPs in MLB; League Avg: 8% — 98th Percentile.

Andrew Abbott has a strike rate of 73% (138/190) in his last two starts — highest in MLB over the last two weeks; League Avg: 65% — 100th Percentile.

Opponents have a chase percentage of 47% (47/99) against Andrew Abbott in his last two starts — highest in MLB over the last two weeks; League Avg: 29% — 100th Percentile.

Opponents are hitting .269 (7-for-26) against Andrew Abbott with two-strikes in his last two starts — 3rd highest in MLB over the last two weeks; League Avg: .153 — fourth Percentile.

Padres Keys to the Game vs. the Reds

The Padres are 11-2 (.846) when they’ve hit 2 or more home runs this season — 4th best in MLB; League Avg: .714.

The Padres are 7-0 (1.000) when they’ve had 5 or more XBH this season — tied for best in MLB; League Avg: .806.

The Padres are 67-56 (.545) on the road since last season — tied for 3rd best in MLB; League Avg: .470.

The Padres are 94-10 (.904) when leading entering the 7th inning since last season — 5th best in MLB; League Avg: .862.

Reds Keys to the Game vs. the Padres

The Reds are just 1-31 (.031) when trailing entering the 7th inning this season — 2nd lowest in MLB; League Avg: .127.

The Reds are just 8-19 (.296) when tied entering the 8th inning since last season — 2nd lowest in MLB; League Avg: .500.

The Reds are just 0-33 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .042.

The Reds are just 16-30 (.348) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Padres have scored first in 91% of their games against division opponents this season — highest in MLB; League Avg: 50%.

The Padres batted .275 on the road in the 2024 season — best in MLB; League Avg: .242.

Padres hitters struck out just 799 times in 4,486 PA’s (18%) against RHP in the 2024 season — best in MLB; League Avg: 23%.

Padres hitters have struck out in just 18% of their PA’s against LHP since last season — best in MLB; League Avg: 23%.

The Reds are batting just .124 on pitches out of the zone since last season — lowest in MLB; League Avg: .149.

Reds hitters have chased 34% of pitches out of the zone with two-strikes this season — lowest in MLB; League Avg: 38%.

Reds hitters are slugging just .169 on pitches out of the zone since last season — lowest in MLB; League Avg: .203.

Reds hitters have a swing rate of just 45% this season — lowest in MLB; League Avg: 48%.

The Padres pitchers have allowed their opponents to score first in just 36% of their games this season — lowest in MLB; League Avg: 50%.

The Padres pitchers have allowed their opponents to score first in just 31% of their games on the road this season — lowest in MLB; League Avg: 43%.

The Padres pitchers have allowed their opponents to score first in just 41% of their games at home this season — 2nd lowest in MLB; League Avg: 57%.

Padres pitchers have a strikeout rate of 45% with two-strikes this season — 4th best in MLB; League Avg: 42%.

Opponents have a groundball rate of just 39% against Reds pitchers since last season — lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in the 2024 season — lowest in MLB; League Avg: 43%.

Reds pitchers have walked 3% of batters when facing the leadoff batter in the inning over the last 14 days — 2nd best in MLB; League Avg: 8%.

Opponents have a groundball rate of just 38% against Reds pitchers this season — 2nd lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.