Padres vs Reds Prediction, Odds & Player Prop Bets Today – MLB, Jun 29

Cincinnati Reds' Elly De La Cruz watches his hit during the first inning of a spring training baseball game against the Cleveland Guardians, Saturday, Feb. 24, 2024, in Goodyear, Ariz.
(AP Photo/Carolyn Kaster)
  • The Reds are -130 favorites vs the Padres
  • Padres vs Reds Over / Under today: 9 Runs
  • Padres / Reds TV Channel: FDOH | PDTV

The San Diego Padres (+110) visit Great American Ball Park to take on the Cincinnati Reds (-130) on Sunday, June 29, 2025. First pitch is scheduled for 1:40pm EDT in Cincinnati, OH, OH.

This season, the Padres are 45-37 against the spread (ATS), while the Reds are 45-37 ATS.

Padres vs Reds Starting Pitchers Today:

  • Padres starting pitcher: Stephen Kolek 3-3, 3.88 ERA
  • Reds starting pitcher: Nick Lodolo 5-5, 3.67 ERA

Padres vs. Reds Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres+1.5 -190O 9.5 -120+110
Reds -1.5 +155U 9.5 +100-130

Padres vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Sunday‘s MLB game with 53.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Sunday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Fernando Tatis Jr. has hit the RBIs Under in 21 of his last 25 away games (+13.95 Units / 26% ROI)
  • Luis Arraez has hit the Singles Under in 15 of his last 25 away games (+11.20 Units / 39% ROI)
  • Fernando Tatis Jr. has hit the Hits Under in 18 of his last 25 games (+10.70 Units / 24% ROI)
  • Jake Cronenworth has hit the Home Runs Over in 2 of his last 4 games (+10.10 Units / 253% ROI)
  • Fernando Tatis Jr. has hit the Total Bases Under in 18 of his last 25 away games (+9.25 Units / 29% ROI)

And here are some favorite MLB player prop bets for Reds players for Sunday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

  • Matt McLain has hit the Singles Over in 15 of his last 25 games at home (+10.00 Units / 39% ROI)
  • Tyler Stephenson has hit the Hits Under in 8 of his last 10 games (+9.85 Units / 84% ROI)
  • Gavin Lux has hit the Home Runs Over in 2 of his last 4 games at home (+9.00 Units / 225% ROI)
  • Tyler Stephenson has hit the Total Bases Under in 9 of his last 10 games (+8.85 Units / 59% ROI)
  • Matt McLain has hit the Runs Over in 13 of his last 20 games (+8.75 Units / 42% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 27 of their last 40 games (+13.30 Units / 28% ROI)
  • The San Diego Padres have hit the Game Total Under in 39 of their last 68 games (+9.30 Units / 12% ROI)
  • The San Diego Padres have hit the Team Total Under in 25 of their last 39 away games (+9.00 Units / 20% ROI)
  • The San Diego Padres have covered the Run Line in 11 of their last 17 away games (+3.70 Units / 16% ROI)
  • The San Diego Padres have hit the Moneyline in 6 of their last 9 games (+2.70 Units / 22% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 36 of their last 60 games (+10.65 Units / 16% ROI)
  • The Cincinnati Reds have hit the Moneyline in 13 of their last 20 games (+7.25 Units / 33% ROI)
  • The Cincinnati Reds have covered the Run Line in 13 of their last 21 games at home (+6.15 Units / 22% ROI)
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 41 of their last 73 games (+5.80 Units / 7% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Over in 10 of their last 14 games (+5.35 Units / 32% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 43-39 against the Run Line (-0.25 Units / -0.23% ROI).

  • 45-37 when betting on the Moneyline for +2.25 Units / 2.06% ROI
  • 34-45 when betting on the total runs Over for -15.05 Units / -16.76% ROI
  • 45-34 when betting on the total runs Under for +7.45 Units / 8.2% ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 45-37 against the Run Line (+1.4 Units / 1.24% ROI).

  • 43-40 when betting on the Moneyline for +0.25 Units / 0.25% ROI
  • 35-46 when betting on the total runs Over for -14.85 Units / -16.38% ROI
  • 46-35 when betting on the total runs Under for +7.6 Units / 8.27% ROI

Reds vs Padres Home Run Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +270 0.5 -350
Fernando Tatis Jr. (SD) 0.5 +375 0.5 -500
Elly De La Cruz (CIN) 0.5 +400 0.5 -550
Jackson Merrill (SD) 0.5 +400 0.5 -550
Christian Encarnacion-Strand (CIN) 0.5 +400 0.5 -550

Reds vs Padres Total Hits Prop Bets Today

Over Under
Elly De La Cruz (CIN) 0.5 -275 0.5 +200
Austin Hays (CIN) 0.5 -250 0.5 +185
Xander Bogaerts (SD) 0.5 -250 0.5 +185
Fernando Tatis Jr. (SD) 0.5 -250 0.5 +190
Matt McLain (CIN) 0.5 -250 0.5 +190

Reds vs Padres RBI Prop Bets Today

Over Under
Elly De La Cruz (CIN) 0.5 +130 0.5 -165
Austin Hays (CIN) 0.5 +130 0.5 -165
Manny Machado (SD) 0.5 +130 0.5 -175
Fernando Tatis Jr. (SD) 0.5 +135 0.5 -175
Xander Bogaerts (SD) 0.5 +160 0.5 -210

Reds vs Padres Strikeout Prop Bets Today

Over Under
Stephen Kolek (SD) 4.5 +115 4.5 -155
Nick Lodolo (CIN) 4.5 +115 4.5 -150

Left handed batters have a Hard-Hit Rate of 59% (51/86) against Stephen Kolek this season — highest in MLB among starting pitchers with at least 32 total IP; League Avg: 42% — first Percentile.

Right-handed batters batted .327 (36-for-110) against Stephen Kolek in the 2024 season — highest among NL Relievers; League Avg: .233 — first Percentile.

Opponents batted .303 (59-for-195) against Stephen Kolek in the 2024 season — 3rd highest among NL Relievers; League Avg: .233 — third Percentile.

Stephen Kolek has a strikeout rate of just 16% (18 SO in 112 PAs) this month (5 games) — 8th lowest among qualified SPs in MLB; League Avg: 23% — eighth Percentile.

Reds Starting Pitcher Stats & Trends

Opponents are hitting .433 (13-for-30) against Nick Lodolo’s low fastballs this season — 2nd highest among qualified SPs in MLB; League Avg: .266 — third Percentile.

Nick Lodolo has not walked any of the 102 opponent 7-8-9 hitters that he has faced this season — best among qualified SPs in MLB; League Avg: 6% — 100th Percentile.

Nick Lodolo has a first-pitch strike rate of 68% (252/372) this season — 10th highest among qualified SPs in MLB; League Avg: 63% — 87th Percentile.

76% of Nick Lodolo’s fastball strikeouts are elevated this season — 3rd highest among qualified SPs in MLB; League Avg: 53% — 96th Percentile.

Padres Keys to the Game vs. the Reds

The Padres are 9-27 (.250) when trailing entering the 7th inning this season — tied for 2nd best in MLB; League Avg: .127.

The Padres are 12-2 (.857) when they’ve hit 2 or more home runs this season — 4th best in MLB; League Avg: .714.

The Padres are 8-0 (1.000) when they’ve had 5 or more XBH this season — tied for best in MLB; League Avg: .807.

The Padres are 79-58 (.577) after a win since last season — 2nd best in MLB; League Avg: .500.

Reds Keys to the Game vs. the Padres

The Reds are just 8-19 (.296) when tied entering the 8th inning since last season — 2nd lowest in MLB; League Avg: .500.

The Reds are just 1-33 (.029) when trailing entering the 8th inning this season — 5th lowest in MLB; League Avg: .091.

The Reds are just 16-30 (.348) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Reds are just 1-31 (.031) when trailing entering the 7th inning this season — 2nd lowest in MLB; League Avg: .127.

Padres hitters have struck out in just 18% of their PA’s against LHP since last season — best in MLB; League Avg: 23%.

Padres hitters have struck out in just 18% of their PA’s against RHP since last season — best in MLB; League Avg: 22%.

The Padres have scored first in 91% of their games against division opponents this season — highest in MLB; League Avg: 50%.

Padres hitters struck out just 799 times in 4,486 PA’s (18%) against RHP in the 2024 season — best in MLB; League Avg: 23%.

Reds hitters have chased 34% of pitches out of the zone with two-strikes this season — lowest in MLB; League Avg: 38%.

The Reds are batting just .223 against LHP since last season — lowest in MLB; League Avg: .244.

Reds hitters have a swing rate of just 45% this season — lowest in MLB; League Avg: 48%.

Reds hitters have an OPS of just .635 (2,804 PA’s) in innings 7-9 since last season — 2nd lowest in MLB; League Avg: .692.

The Padres pitchers have allowed their opponents to score first in just 37% of their games this season — lowest in MLB; League Avg: 50%.

Opponents have a miss rate of 27% against Padres pitchers since last season — 4th best in MLB; League Avg: 25%.

The Padres pitchers have allowed their opponents to score first in just 41% of their games at home this season — 2nd lowest in MLB; League Avg: 56%.

Opponents have a groundball rate of just 37% against Padres pitchers over the last 14 days — 3rd lowest in MLB; League Avg: 42%.

Opponents have a groundball rate of just 38% against Reds pitchers this season — 2nd lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 39% against Reds pitchers since the 2023 season — tied for lowest in MLB; League Avg: 43%.

Reds pitchers have walked 2% of batters when facing the leadoff batter in the inning over the last 14 days — 2nd best in MLB; League Avg: 8%.

Opponents have a groundball rate of just 39% against Reds pitchers since last season — lowest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.