• The Padres are -155 favorites vs the Reds
• Padres vs Reds Over / Under today: 9.5 Runs
• Padres / Reds TV Channel: RDTV | PDTV

The San Diego Padres (-155) visit Great American Ball Park to take on the Cincinnati Reds (+125) on September 2, 2026. First pitch is scheduled for 12:40 pm in Cincinnati, OH.

This season, the Padres are against the spread (ATS), while the Reds are ATS.

Padres vs Reds Starting Pitchers Today:

• Padres starting pitcher: Casey Mize 5-8, 3.43 ERA
• Reds starting pitcher: Brandon Williamson 2-3, 6.11 ERA

Padres vs. Reds Odds, Run Line, Over/Under & Moneyline

Padres vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 60.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Padres vs Reds and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

• Fernando Tatis Jr. has hit the Singles Under in 16 of his last 20 away games (+12.75 Units / 61% ROI)
• Manny Machado has hit the RBIs Under in 20 of his last 25 games (+10.80 Units / 21% ROI)
• Freddy Fermin has hit the Hits Over in 19 of his last 25 games (+10.60 Units / 31% ROI)
• Jackson Merrill has hit the Runs Over in 15 of his last 25 games (+10.05 Units / 40% ROI)
• Freddy Fermin has hit the Total Bases Over in 18 of his last 25 games (+9.45 Units / 28% ROI)

And here are some favorite MLB player prop bets for Reds players for Wednesday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

• Hector Rodriguez has hit the Home Runs Over in 3 of his last 9 games (+19.90 Units / 221% ROI)
• TJ Friedl has hit the Hits Under in 18 of his last 25 games (+11.50 Units / 43% ROI)
• JJ Bleday has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+11.25 Units / 34% ROI)
• Elly De La Cruz has hit the Total Bases Under in 13 of his last 15 games at home (+10.30 Units / 48% ROI)
• TJ Friedl has hit the Runs Under in his last 10 games (+10.00 Units / 41% ROI)

Padres Best Bets Today:

• The San Diego Padres have covered the Run Line in 28 of their last 45 games (+14.65 Units / 25% ROI)
• The San Diego Padres have hit the Team Total Over in 28 of their last 45 games (+9.55 Units / 19% ROI)
• The San Diego Padres have hit the Moneyline in 22 of their last 35 games (+6.80 Units / 15% ROI)
• The San Diego Padres have hit the Game Total Under in 13 of their last 22 games (+5.35 Units / 22% ROI)
• The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 7 of their last 10 games (+3.35 Units / 28% ROI)

Reds Best Bets Today:

• The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 31 of their last 45 games at home (+14.95 Units / 27% ROI)
• The Cincinnati Reds have hit the Team Total Under in 31 of their last 45 games at home (+14.60 Units / 28% ROI)
• The Cincinnati Reds have hit the Game Total Under in 25 of their last 40 games at home (+9.85 Units / 22% ROI)
• The Cincinnati Reds have hit the Moneyline in 4 of their last 6 games (+3.20 Units / 53% ROI)
• The Cincinnati Reds have covered the Run Line in 4 of their last 6 games (+1.65 Units / 20% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Reds vs Padres Home Run Prop Bets Today

Reds vs Padres Total Hits Prop Bets Today

Reds vs Padres Strikeout Prop Bets Today

Padres Keys to the Game vs. the Reds

The Padres are 57-2 (.966) when leading entering the 8th inning this season — 4th best in MLB.

The Padres are 11-53 (.172) when trailing entering the 7th inning this season — 5th best in MLB.

The Padres are 33-18 (.647) vs the bottom 10 runs allowed teams this season Today, they face the Reds (26th fewest runs allowed).

The Padres are 132-7 (.950) when leading entering the 8th inning since the 2025 season — 2nd best in MLB.

Reds Keys to the Game vs. the Padres

The Reds are just 8-17 (.320) when tied entering the 7th inning this season — 5th lowest in MLB.

The Reds are just 28-37 (.431) after a win this season — 5th lowest in MLB.

The Reds are 7-65 (.097) when trailing entering the 9th inning this season — 3rd best in MLB.

The Reds are 50-15 (.769) when allowing 4 or fewer runs this season — tied for 3rd best in MLB.

Padres Hitting Stats & Trends

Padres hitters have grounded into 111 double plays in 923 opportunities (12%) this season — highest in MLB.

Padres hitters are slugging just .368 at home this season — 3rd lowest in MLB.

Padres hitters have an OPS of just .682 (2,506 PA’s) at home this season — 4th lowest in MLB.

The Padres are batting just .233 at home this season — 5th lowest in MLB.

Reds Hitting Stats & Trends

The Reds are batting just .228 this season — tied for lowest in MLB.

The Reds are batting just .207 with two outs this season — lowest in MLB.

The Reds are batting just .218 at home this season — lowest in MLB.

Reds hitters have struck out in 25% of their PA’s against RHP this season — highest in MLB.

Padres Pitching Stats & Trends

The longest HR allowed by the Padres pitchers this season traveled 453.0 feet — — 5th longest in MLB

Padres pitchers have allowed an exit velocity over 105 MPH 246 times this season — 3rd fewest in MLB.

Padres pitchers have allowed innings of 3+ runs in 4% of innings played this season — tied for 2nd lowest in MLB.

The Padres have allowed 1.09 runs per game (151/139) in late innings this season — 3rd best in MLB.

Reds Pitching Stats & Trends

Reds pitchers have walked 10% of batters this season — 3rd highest in MLB.

The Reds pitchers have allowed their opponents to score first in 61% of their games this season — highest in MLB.

The Reds pitchers have allowed their opponents to score first in 67% of their games at home this season — 2nd highest in MLB.

Reds pitchers have an ERA of 5.16 (595.1 IP) on the road this season — 2nd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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