• The Philadelphia Phillies are -150 favorites vs the Houston Astros
• Philadelphia Phillies vs Houston Astros Over / Under today: 7.5 Runs
• Philadelphia Phillies / Houston Astros TV Channel: NSPA | SCHN | SCH2

The Philadelphia Phillies (-150) visit Daikin Park to take on the Houston Astros (+125) on Wednesday, June 25, 2025. First pitch is scheduled for 8:10pm EDT in Houston, TX, TX.

This season, the Philadelphia Phillies are 47-32 against the spread (ATS), while the Houston Astros are 40-39 ATS.

Philadelphia Phillies vs Houston Astros Starting Pitchers Today:

• Philadelphia Phillies starting pitcher: , ERA
• Houston Astros starting pitcher: , ERA

Philadelphia Phillies vs. Houston Astros Odds, Run Line, Over/Under & Moneyline

Philadelphia Phillies vs Houston Astros Prediction for Today’s Game

Based on recent trends the model predicts the will win Wednesday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Philadelphia Phillies vs Houston Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Philadelphia Phillies players for Wednesday‘s game, looking at profitable historical betting trends:

Best Philadelphia Phillies Player Prop Bets Today:

• Trea Turner has hit the Hits Over in 16 of his last 25 away games (+12.30 Units / 39% ROI)
• Trea Turner has hit the Home Runs Over in 2 of his last 5 away games (+11.10 Units / 222% ROI)
• Trea Turner has hit the Total Bases Over in 17 of his last 25 away games (+10.95 Units / 41% ROI)
• Zack Wheeler has hit the Strikeouts Over in 15 of his last 20 games (+9.90 Units / 40% ROI)
• Zack Wheeler has hit the Hits Allowed Under in 17 of his last 25 games (+9.35 Units / 33% ROI)

And here are some favorite MLB player prop bets for Houston Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Houston Astros Player Prop Best Bets Today:

• Jeremy Pena has hit the Hits Over in 18 of his last 25 games at home (+18.35 Units / 49% ROI)
• Jeremy Pena has hit the Singles Over in 19 of his last 25 games at home (+10.10 Units / 28% ROI)
• Jeremy Pena has hit the Total Bases Over in 14 of his last 20 games at home (+9.95 Units / 49% ROI)
• Victor Caratini has hit the Home Runs Over in 2 of his last 4 games (+9.90 Units / 247% ROI)
• Jeremy Pena has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+8.95 Units / 26% ROI)

Philadelphia Phillies Best Bets Today:

• The Philadelphia Phillies have hit the 1st Five Innings (F5) Moneyline in 35 of their last 61 games (+15.75 Units / 16% ROI)
• The Philadelphia Phillies have covered the 1st Five Innings (F5) Run Line in 45 of their last 75 games (+13.28 Units / 14% ROI)
• The Philadelphia Phillies have hit the Game Total Under in 23 of their last 35 away games (+11.00 Units / 28% ROI)
• The Philadelphia Phillies have hit the 1st Five Innings (F5) Team Total Under in 25 of their last 39 away games (+9.70 Units / 21% ROI)
• The Philadelphia Phillies have hit the Moneyline in 34 of their last 53 games (+8.50 Units / 10% ROI)

Houston Astros Best Bets Today:

• The Houston Astros have hit the Moneyline in 25 of their last 33 games at home (+15.10 Units / 33% ROI)
• The Houston Astros have hit the Team Total Under in 48 of their last 79 games (+13.75 Units / 15% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 24 of their last 36 games at home (+10.40 Units / 24% ROI)
• The Houston Astros have hit the Game Total Under in 28 of their last 46 games (+9.65 Units / 19% ROI)
• The Houston Astros have covered the Run Line in 20 of their last 35 games at home (+7.52 Units / 18% ROI)

Philadelphia Phillies Against the Spread (ATS) Record

Against the spread this season, the Philadelphia Phillies are 39-39 against the Run Line (-2.6 Units / -2.67% ROI).

• 47-32 when betting on the Moneyline for +4.5 Units / 3.61% ROI
• 34-42 when betting on the total runs Over for -12.05 Units / -13.84% ROI
• 42-34 when betting on the total runs Under for +4.9 Units / 5.65% ROI

Houston Astros Against the Spread (ATS) Record

Against the spread this season, the Houston Astros are 40-39 against the Run Line (+2.22 Units / 2.25% ROI).

• 46-33 when betting on the Moneyline for +6.3 Units / 6.06% ROI
• 32-44 when betting on the total runs Over for -15.95 Units / -18.45% ROI
• 44-32 when betting on the total runs Under for +8.9 Units / 10.18% ROI

Houston Astros vs Philadelphia Phillies Home Run Prop Bets Today

Houston Astros vs Philadelphia Phillies Total Hits Prop Bets Today

Houston Astros vs Philadelphia Phillies RBI Prop Bets Today

Houston Astros vs Philadelphia Phillies Strikeout Prop Bets Today

Philadelphia Phillies Starting Pitcher Stats & Trends

starting pitcher – away

Houston Astros Starting Pitcher Stats & Trends

starting pitcher – home

Philadelphia Phillies Keys to the Game vs. the Houston Astros

keys to the game – away

Houston Astros Keys to the Game vs. the Philadelphia Phillies

keys to the game – home

Philadelphia Phillies Hitting Stats & Trends

team hitters – away

Houston Astros Hitting Stats & Trends

team hitters – home

Philadelphia Phillies Pitching Stats & Trends

team pitchers – away

Houston Astros Pitching Stats & Trends

team pitchers – home

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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