• The Phillies are -165 favorites vs the Cardinals
• Phillies vs Cardinals Over / Under today: 8 Runs
• Phillies / Cardinals TV Channel: CATV | NSPA

The Philadelphia Phillies (-165) visit Busch Stadium to take on the St. Louis Cardinals (+135) on August 12, 2026. First pitch is scheduled for 2:15 pm in St. Louis, MO.

This season, the Phillies are 64-57 against the spread (ATS), while the Cardinals are 65-52 ATS.

Phillies vs Cardinals Starting Pitchers Today:

• Phillies starting pitcher: Zack Wheeler 10-3, 2.70 ERA
• Cardinals starting pitcher: Quinn Mathews 0-1, 3.60 ERA

Phillies vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Phillies vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Phillies will win Wednesday‘s MLB game with 57.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Phillies vs Cardinals and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Phillies players for Wednesday‘s game, looking at profitable historical betting trends:

Best Phillies Player Prop Bets Today:

• Brandon Marsh has hit the Total Bases Under in 20 of his last 25 games (+13.00 Units / 32% ROI)
• Alec Bohm has hit the Hits Runs and RBIs Under in 18 of his last 25 away games (+11.95 Units / 43% ROI)
• J.T. Realmuto has hit the Singles Under in 19 of his last 25 away games (+11.40 Units / 36% ROI)
• Trea Turner has hit the Home Runs Over in 2 of his last 5 away games (+10.50 Units / 210% ROI)
• J.T. Realmuto has hit the Runs Over in 8 of his last 10 away games (+10.50 Units / 105% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• JJ Wetherholt has hit the Hits Under in 16 of his last 25 games at home (+13.45 Units / 43% ROI)
• Ivan Herrera has hit the Walks Under in his last 10 games at home (+10.00 Units / 43% ROI)
• Nathan Church has hit the Singles Over in 9 of his last 10 games (+9.35 Units / 90% ROI)
• Cesar Prieto has hit the Hits Runs and RBIs Under in his last 8 games (+9.10 Units / 94% ROI)
• Masyn Winn has hit the Total Bases Over in 8 of his last 10 games at home (+8.10 Units / 64% ROI)

Phillies Best Bets Today:

• The Philadelphia Phillies have hit the Game Total Under in 29 of their last 45 away games (+12.70 Units / 26% ROI)
• The Philadelphia Phillies have hit the 1st Five Innings (F5) Team Total Under in 27 of their last 45 away games (+6.40 Units / 12% ROI)
• The Philadelphia Phillies have hit the Moneyline in 27 of their last 45 away games (+5.75 Units / 10% ROI)
• The Philadelphia Phillies have hit the 1st Five Innings (F5) Moneyline in 5 of their last 6 away games (+5.00 Units / 55% ROI)
• The Philadelphia Phillies have covered the 1st Five Innings (F5) Run Line in 8 of their last 11 away games (+4.30 Units / 32% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Game Total Under in 30 of their last 45 games (+14.75 Units / 30% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 21 of their last 30 games at home (+11.85 Units / 34% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 22 games (+9.60 Units / 35% ROI)
• The St. Louis Cardinals have hit the Moneyline in 6 of their last 9 games (+4.25 Units / 39% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 19 of their last 40 games (+4.00 Units / 9% ROI)

Phillies Against the Spread (ATS) Record

Against the spread this season, the Phillies are 46-74 against the Run Line (-34.95 Units / -24.48% ROI).

• 64-57 when betting on the Moneyline for -9.9 Units / -5.48% ROI
• 53-62 when betting on the total runs Over for -14.95 Units / -11.21% ROI
• 62-53 when betting on the total runs Under for +4.15 Units / 3.12% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 65-52 against the Run Line (-1.5 Units / -0.89% ROI).

• 60-60 when betting on the Moneyline for +4.4 Units / 3.37% ROI
• 48-67 when betting on the total runs Over for -26.2 Units / -19.77% ROI
• 67-48 when betting on the total runs Under for +14.1 Units / 10.71% ROI

Cardinals vs Phillies Home Run Prop Bets Today

Cardinals vs Phillies Total Hits Prop Bets Today

Cardinals vs Phillies Strikeout Prop Bets Today

Phillies Keys to the Game vs. the Cardinals

The Phillies were 15-45 (.250) when trailing entering the 7th inning in the 2025 season — best in MLB; League Avg: .124.

The Phillies were 51-9 (.850) when they had 10 or more hits in the 2024 season — 2nd best in MLB; League Avg: .750.

The Phillies were 35-5 (.875) when they had 5 or more XBH in the 2025 season — tied for 4th best in MLB; League Avg: .799.

The Phillies were 5-56 (.082) when trailing entering the 9th inning in the 2024 season — 3rd best in MLB; League Avg: .050.

Cardinals Keys to the Game vs. the Phillies

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

The Cardinals were 69-1 (.986) when leading entering the 9th inning in the 2024 season — tied for 2nd best in MLB; League Avg: .949.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

Phillies Hitting Stats & Trends

Phillies hitters have an OBP of just .229 (2,440 PA’s) with two-strikes this season — 2nd lowest in MLB.

Phillies hitters are slugging .722 with the pitcher behind in the count this season — best in MLB.

Phillies hitters are slugging just .361 on the road this season — tied for 2nd lowest in MLB.

Phillies hitters have an OPS of 1.226 (838 PA’s) with the pitcher behind in the count this season — best in MLB.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 18% of their PA’s against LHP this season — tied for 2nd best in MLB.

Cardinals hitters have an OBP of just .306 (2,373 PA’s) at home this season — 2nd lowest in MLB.

Cardinals hitters are slugging just .361 at home this season — 2nd lowest in MLB.

Cardinals hitters are slugging just .379 this season — 5th lowest in MLB.

Phillies Pitching Stats & Trends

Phillies pitchers have allowed an average Exit Velocity of 87.7 MPH (2,917 batted balls) this season — tied for best in MLB.

The Phillies pitchers have allowed an average Exit Velocity of just 87.7 MPH this season (2,917 balls in play) — tied for best in MLB

Phillies pitchers have a strikeout rate of 26% this season — 2nd best in MLB.

Phillies pitchers have a strikeout rate of 47% with two-strikes this season — best in MLB.

Cardinals Pitching Stats & Trends

The Cardinals pitchers have allowed their opponents to score first in just 33% of their games on the road this season — lowest in MLB.

Opponents have a groundball rate of 46% against Cardinals pitchers this season — 3rd highest in MLB.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes this season — 5th lowest in MLB.

Cardinals pitchers have a strikeout rate of just 19% with runners in scoring position this season — tied for 3rd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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